Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells (Q37736265)

22 August 2017

1 reference

title

Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells (English)

1 reference

22 August 2017

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Christopher K Glass

1

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PubMed ID

20414208

22 August 2017

Kaoru Saijo

series ordinal

2

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22 August 2017

1 May 2010

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Nature Reviews Immunology

22 August 2017

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22 August 2017

10

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22 August 2017

365-376

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22 August 2017

5

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Nuclear receptors and lipid physiology: opening the X-files

22 August 2017

1 reference

The nuclear receptor superfamily: the second decade

31 March 2020

1 reference

Combinatorial roles of nuclear receptors in inflammation and immunity

31 March 2020

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Glucocorticoids and the innate immune system: crosstalk with the toll-like receptor signaling network.

31 March 2020

1 reference

Transcriptional regulatory networks in Th17 cell differentiation

31 March 2020

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Toll-like receptors and innate immunity

31 March 2020

1 reference

Toll-like receptors in systemic autoimmune disease

31 March 2020

1 reference

Toll-like receptor 4-dependent and -independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages.

31 March 2020

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TLR4 links innate immunity and fatty acid-induced insulin resistance

31 March 2020

1 reference

A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways

31 March 2020

1 reference

Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease.

31 March 2020

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Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity

31 March 2020

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Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

31 March 2020

1 reference

Modulation of atherosclerosis in mice by Toll-like receptor 2

31 March 2020

1 reference

C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet

31 March 2020

1 reference

Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice

31 March 2020

1 reference

Toll-like receptor signalling

31 March 2020

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Type I interferons (alpha/beta) in immunity and autoimmunity

31 March 2020

1 reference

Stimulus specificity of gene expression programs determined by temporal control of IKK activity

31 March 2020

1 reference

Defining requirements for heterodimerization between the retinoid X receptor and the orphan nuclear receptor Nurr1.

31 March 2020

1 reference

Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation

31 March 2020

1 reference

Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors

31 March 2020

1 reference

Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response

31 March 2020

1 reference

Cracking the coregulator codes

31 March 2020

1 reference

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

31 March 2020

1 reference

Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance.

31 March 2020

1 reference

FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription

31 March 2020

1 reference

Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1

31 March 2020

1 reference

PPARgamma and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

31 March 2020

1 reference

Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis

31 March 2020

1 reference

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

31 March 2020

1 reference

31 March 2020

1 reference

A Nuclear Receptor Atlas: macrophage activation

31 March 2020

1 reference

Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network

31 March 2020

1 reference

Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.

31 March 2020

1 reference

The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression

31 March 2020

1 reference

Corticosteroids Reduce IL-6 in ASM Cells via Up-Regulation of MKP-1

31 March 2020

1 reference

Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition

31 March 2020

1 reference

A novel mitogen-activated protein kinase phosphatase-1 and glucocorticoid receptor (GR) interacting protein-1-dependent combinatorial mechanism of gene transrepression by GR

31 March 2020

1 reference

Restriction to Fos family members of Trip6-dependent coactivation and glucocorticoid receptor-dependent trans-repression of activator protein-1.

31 March 2020

1 reference

Minireview: latest perspectives on antiinflammatory actions of glucocorticoids

31 March 2020

1 reference

One nucleotide in a kappaB site can determine cofactor specificity for NF-kappaB dimers

31 March 2020

1 reference

The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression.

31 March 2020

1 reference

Control of inducible gene expression by signal-dependent transcriptional elongation

31 March 2020

1 reference

Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts

31 March 2020

1 reference

Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones

31 March 2020

1 reference

A nuclear isoform of the focal adhesion LIM-domain protein Trip6 integrates activating and repressing signals at AP-1- and NF-kappaB-regulated promoters

31 March 2020

1 reference

A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation

31 March 2020

1 reference

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

31 March 2020

1 reference

A transcriptional co-repressor that interacts with nuclear hormone receptors

31 March 2020

1 reference

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

31 March 2020

1 reference

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

31 March 2020

1 reference

A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors

31 March 2020

1 reference

Estrogen down-regulation of the corepressor N-CoR: mechanism and implications for estrogen derepression of N-CoR-regulated genes

31 March 2020

1 reference

Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

31 March 2020

1 reference

A nuclear receptor corepressor-dependent pathway mediates suppression of cytokine-induced C-reactive protein gene expression by liver X receptor

31 March 2020

1 reference

GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response

31 March 2020

1 reference

Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint

31 March 2020

1 reference

The SMRT corepressor is regulated by a MEK-1 kinase pathway: inhibition of corepressor function is associated with SMRT phosphorylation and nuclear export

31 March 2020

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SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways

31 March 2020

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MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma

31 March 2020

1 reference

SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron

31 March 2020

1 reference

Differential SUMOylation of LXRalpha and LXRbeta mediates transrepression of STAT1 inflammatory signaling in IFN-gamma-stimulated brain astrocytes.

31 March 2020

1 reference

A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death

31 March 2020

1 reference

Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity

31 March 2020

1 reference

Glucocorticoids in T cell development and function*.

31 March 2020

1 reference

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

31 March 2020

1 reference

Pathophysiology of multiple sclerosis

31 March 2020

1 reference

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

31 March 2020

1 reference

The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity

31 March 2020

1 reference

Orphan nuclear receptor NR4A2 expressed in T cells from multiple sclerosis mediates production of inflammatory cytokines

31 March 2020

1 reference

The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity

31 March 2020

1 reference

Traditional concepts and future avenues of glucocorticoid action in experimental autoimmune encephalomyelitis and multiple sclerosis therapy

31 March 2020

1 reference

Peripheral T cells are the therapeutic targets of glucocorticoids in experimental autoimmune encephalomyelitis.

31 March 2020

1 reference

Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.

31 March 2020

1 reference

PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance

31 March 2020

1 reference

PPARgamma-dependent regulation of human macrophages in phagocytosis of apoptotic cells.

31 March 2020

1 reference

Biological roles and mechanistic actions of co-repressor complexes

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20414208

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The effect of a hormone of the adrenal cortex (17-hydroxy-11-dehydrocorticosterone; compound E) and of pituitary adrenocorticotropic hormone on rheumatoid arthritis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20414208

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/20414208

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRI2748

1 reference

22 August 2017

1 reference

PubMed ID

20414208