The endothelium: physiological functions and role in microcirculatory failure during severe sepsis (Q37742508)

22 August 2017

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title

The endothelium: physiological functions and role in microcirculatory failure during severe sepsis (English)

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22 August 2017

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H Ait-Oufella

1

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22 August 2017

E Maury

2

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22 August 2017

S Lehoux

3

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22 August 2017

B Guidet

4

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22 August 2017

G Offenstadt

5

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22 August 2017

language of work or name

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5 May 2010

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22 August 2017

Intensive Care Medicine

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22 August 2017

36

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22 August 2017

8

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22 August 2017

1286-1298

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https://scigraph.springernature.com/pub.10.1007/s00134-010-1893-6

22 August 2017

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cites work

Circulating endothelial cells in patients with septic shock.

1 reference

https://api.crossref.org/works/10.1007%2FS00134-010-1893-6

Circulating ICAM-1 is increased in septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-010-1893-6

Increased circulating cytokines, cytokine antagonists, and E-selectin after intravenous administration of endotoxin in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-010-1893-6

Elevated circulating E-selectin, intercellular adhesion molecule 1, and von Willebrand factor in patients with severe infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-010-1893-6

Tissue factor-dependent coagulation is preferentially up-regulated within arterial branching areas in a baboon model of Escherichia coli sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-010-1893-6

Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-010-1893-6

Effects of the angiotensin-converting enzyme inhibitor perindopril on endothelial injury and hemostasis in rabbit endotoxic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-010-1893-6

Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-010-1893-6

Nitric oxide modulates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00134-010-1893-6

Effect of L-arginine on endothelial injury and hemostasis in rabbit endotoxin shock

21 January 2018

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12 December 2020

Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate

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12 December 2020

Protein C anticoagulant pathway and its role in controlling microvascular thrombosis and inflammation

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12 December 2020

Flow-mediated endothelial mechanotransduction

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12 December 2020

Pathogenetic mechanisms of septic shock

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12 December 2020

Protease-activated receptor 3 is a second thrombin receptor in humans

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12 December 2020

Endotoxin-induced ileal mucosal hyperpermeability in pigs: role of tissue acidosis

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12 December 2020

Thrombomodulin, an endothelial anticoagulant protein, is absent from the human brain.

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12 December 2020

Tumor necrosis factor-alpha and lipopolysaccharide induce apoptotic cell death in bovine glomerular endothelial cells

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12 December 2020

Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands

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12 December 2020

Contrasting effects of colloid and crystalloid resuscitation fluids on cardiac vascular permeability

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12 December 2020

Endothelial "stunning" following a brief exposure to endotoxin: a mechanism to link infection and infarction?

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12 December 2020

Tissue factor expression by endothelial cells in sickle cell anemia

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12 December 2020

Modulation of endothelial cell hemostatic properties by tumor necrosis factor

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12 December 2020

The tissue factor and plasminogen activator inhibitor type-1 response in pediatric sepsis-induced multiple organ failure

1 reference

12 December 2020

Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis

1 reference

12 December 2020

Electron microscopic studies on specific organelles of endothelial cells in the frog (Rana temporaria)

1 reference

12 December 2020

Endothelial cell heterogeneity

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12 December 2020

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon

1 reference

12 December 2020

Local venous responses to endotoxin in humans

1 reference

12 December 2020

Effects of Nitric Oxide in Septic Shock

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12 December 2020

Platelet-activating factor mediates procoagulant activity on the surface of endothelial cells by promoting leukocyte adhesion

1 reference

12 December 2020

Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis

1 reference

12 December 2020

Can graft endothelial cells initiate a host anti-graft immune response?

1 reference

12 December 2020

The coagulation cascade in sepsis

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12 December 2020

Effects of N omega-nitro-L-arginine methyl ester on the endotoxin-induced disseminated intravascular coagulation in porcine septic shock.

1 reference

12 December 2020

Inhibition of the biologic activity of tumor necrosis factor maintains vascular endothelial cell function during hyperdynamic sepsis

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12 December 2020

Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture

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12 December 2020

Physiological consequences of loss of plasminogen activator gene function in mice

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12 December 2020

Organ Distribution of Fibrin in Disseminated Intravascular Coagulation

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12 December 2020

In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant.

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12 December 2020

Increased tissue thromboplastin activity in monocytes of patients with meningococcal infection: related to an unfavourable prognosis

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12 December 2020

Biochemistry of heparin antithrombin interactions, and the physiologic role of this natural anticoagulant mechanism

1 reference

12 December 2020

Circulating microparticles: pathophysiology and clinical implications.

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12 December 2020

Major histocompatibility complex class II-expressing endothelial cells induce allospecific nonresponsiveness in naive T cells

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12 December 2020

Effects of nitric oxide synthase inhibition on regional hemodynamics and oxygen transport in endotoxic dogs

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12 December 2020

Leukocyte-endothelial interactions: clinical trials of anti-adhesion therapy

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12 December 2020

The endothelial glycocalyx: composition, functions, and visualization

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12 December 2020

Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice.

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12 December 2020

Colloidal gold particles as a new in vivo marker of early acute lung injury

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12 December 2020

Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock

1 reference

12 December 2020

Endothelial cell-to-cell junctions.

1 reference

12 December 2020

Fine structures of capillary and endocapillary layer as revealed by ruthenium red

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12 December 2020

Natural regulatory T cells control the development of atherosclerosis in mice

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12 December 2020

Disseminated intravascular coagulation

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12 December 2020

Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration

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12 December 2020

Heparin cofactor II activity in patients with disseminated intravascular coagulation and hepatic failure

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12 December 2020

Vascular bed-specific expression of an endothelial cell gene is programmed by the tissue microenvironment

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12 December 2020

Monocyte-selective transendothelial migration: dissection of the binding and transmigration phases by an in vitro assay

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12 December 2020

Hydrolase activities in the rat aorta. IV. Relation between clearance rates of circulating 125I-labeled low-density lipoproteins and levels of tissue hydrolase activity

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12 December 2020

The histological localisation of fibrinolysin activator

1 reference

12 December 2020

Nitric oxide and peroxynitrite in health and disease

1 reference

12 December 2020

Divergent roles of endothelial NF-kappaB in multiple organ injury and bacterial clearance in mouse models of sepsis

1 reference

12 December 2020

Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial

1 reference

12 December 2020

Platelets support pulmonary recruitment of neutrophils in abdominal sepsis

1 reference

12 December 2020

Regulation of thrombin receptors on human umbilical vein endothelial cells

1 reference

12 December 2020

Induction of endothelial cell apoptosis by TNF alpha: modulation by inhibitors of protein synthesis

1 reference

12 December 2020

Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock

1 reference

12 December 2020

Tissue factor in cardiovascular diseases: molecular mechanisms and clinical implications

1 reference

12 December 2020

Endothelial apoptosis: could it have a role in the pathogenesis and treatment of disease?

1 reference

12 December 2020

Mechanisms of diabetic vasculopathy: an overview.

1 reference

12 December 2020

Protein kinase C and the stimulation of tissue plasminogen activator release from human endothelial cells. Dependence on the elevation of messenger RNA.

1 reference

12 December 2020

Advances in the pathogenesis, diagnosis, and treatment of thrombotic thrombocytopenic purpura

1 reference

12 December 2020

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1 reference

12 December 2020

Ischemia, hyperemia, exercise, and nitric oxide. Complex physiology and complex molecular adaptations

1 reference

12 December 2020

Vascular bed-specific hemostasis: role of endothelium in sepsis pathogenesis

1 reference

12 December 2020

Differential hemodynamic effects of L-NMMA in endotoxemic and normal dogs

1 reference

12 December 2020

A single endotoxin injection in the rabbit causes prolonged blood vessel dysfunction and a procoagulant state

1 reference

12 December 2020

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1

1 reference

12 December 2020

Plasminogen activator inhibitor type 1 gene polymorphism and sepsis

1 reference

12 December 2020

Efficacy and safety of recombinant human activated protein C for severe sepsis

1 reference

12 December 2020

Activation of the fibrinolytic system and utilization of the coagulation inhibitors in sepsis: comparison with severe sepsis and septic shock

1 reference

12 December 2020

Permeation of the luminal capillary glycocalyx is determined by hyaluronan

1 reference

12 December 2020

Endothelial cell injury in cardiovascular surgery: the intimal hyperplastic response.

1 reference

12 December 2020

Microvascular blood flow is altered in patients with sepsis

1 reference

12 December 2020

Redox signalling in vascular responses to shear and stretch

1 reference

12 December 2020

Activated protein C for sepsis

1 reference

12 December 2020

Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death

1 reference

12 December 2020

Platelets and blood vessels: the adhesion event

1 reference

12 December 2020

Differentiation of endothelial cells: analysis of the constitutive and activated endothelial cell phenotypes

1 reference

12 December 2020

Stimulation of P-selectin glycoprotein ligand-1 on mouse neutrophils activates β2 -integrin mediated cell attachment to ICAM-1

1 reference

12 December 2020

Endothelial cell glycocalyx modulates immobilization of leukocytes at the endothelial surface

1 reference

12 December 2020

Nitric oxide: physiology, pathophysiology, and pharmacology

1 reference

12 December 2020

Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro

1 reference

12 December 2020

Leukocyte trafficking mediated by selectin-carbohydrate interactions

1 reference

12 December 2020

Inflammatory response in microvascular endothelium in sepsis: role of oxidants.

1 reference

12 December 2020

Plasticity of endothelial cells: rapid dedifferentiation of freshly isolated high endothelial venule endothelial cells outside the lymphoid tissue microenvironment

1 reference

12 December 2020

Platelets and the injured vessel wall-- "rolling into action": focus on glycoprotein Ib/V/IX and the platelet cytoskeleton

1 reference

12 December 2020

Fibrin deposition in tissues from endotoxin-treated mice correlates with decreases in the expression of urokinase-type but not tissue-type plasminogen activator

1 reference

12 December 2020

Biochemistry of Nitric Oxide and Its Redox-Activated Forms

1 reference

12 December 2020

Endothelial glycocalyx damage during endotoxemia coincides with microcirculatory dysfunction and vascular oxidative stress

1 reference

12 December 2020

Endothelial injury and regeneration. IV. Endotoxin: a nondenuding injury to aortic endothelium

1 reference

12 December 2020

The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: relationship with activation of coagulation

1 reference

12 December 2020

Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1-dependent pathway

1 reference

12 December 2020

Prognostic value of protein C concentrations in neutropenic patients at high risk of severe septic complications

1 reference

12 December 2020

Endothelial nitric oxide synthase is downregulated during hyperdynamic sepsis

1 reference

12 December 2020

Circulating adhesion molecules in the critically ill: a comparison between trauma and sepsis patients

1 reference

12 December 2020

The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells

1 reference

12 December 2020

Characterization of human endothelial cell urokinase-type plasminogen activator receptor protein and messenger RNA.

1 reference

12 December 2020

Tissue factor pathway inhibitor

1 reference

12 December 2020

Antioxidant eugenosedin-A protects against lipopolysaccharide-induced hypotension, hyperglycaemia and cytokine immunoreactivity in rats and mice.

1 reference

12 December 2020

Platelet-activating factor: a mediator for clinicians

1 reference

12 December 2020

Depletion of extrinsic pathway inhibitor (EPI) sensitizes rabbits to disseminated intravascular coagulation induced with tissue factor: evidence supporting a physiologic role for EPI as a natural anticoagulant

1 reference

12 December 2020

Porcine aortic endothelial cells activate human T cells: direct presentation of MHC antigens and costimulation by ligands for human CD2 and CD28

1 reference

12 December 2020

Natural anticoagulant mechanisms

1 reference

12 December 2020

Modulation of adhesion molecule expression on endothelial cells after induction by lipopolysaccharide-stimulated whole blood.

1 reference

12 December 2020

An open-label dose escalation study of the nitric oxide synthase inhibitor, N(G)-methyl-L-arginine hydrochloride (546C88), in patients with septic shock. Glaxo Wellcome International Septic Shock Study Group.

1 reference

12 December 2020

Veno-occlusive disease of the liver

1 reference

12 December 2020

Regulation of intestinal nuclear factor-kappaB activity and E-selectin expression during sepsis: a role for peroxynitrite

1 reference

12 December 2020

1 reference

12 December 2020

Measuring endothelial glycocalyx dimensions in humans: a potential novel tool to monitor vascular vulnerability

1 reference

12 December 2020

Inhibition by human thrombomodulin of factor Xa-mediated cleavage of prothrombin

1 reference

12 December 2020

Time-dependent effects of endotoxin on the ultrastructure of aortic endothelium

1 reference

12 December 2020

Drotrecogin alfa (activated) in children with severe sepsis: a multicentre phase III randomised controlled trial.

1 reference

12 December 2020

Apoptotic vascular endothelial cells become procoagulant

1 reference

12 December 2020

Skin biopsies demonstrate site-specific endothelial activation in mouse models of sepsis.

1 reference

12 December 2020

The endothelial cell protein C receptor. Cell surface expression and direct ligand binding by the soluble receptor

1 reference

12 December 2020

The beneficial effects of antioxidant supplementation in enteral feeding in critically ill patients: a prospective, randomized, double-blind, placebo-controlled trial.

1 reference

12 December 2020

Levels of endothelial and platelet microparticles and their interactions with leukocytes negatively correlate with organ dysfunction and predict mortality in severe sepsis.

1 reference

12 December 2020

10.1007/S00134-010-1893-6

Identifiers

DOI

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22 August 2017

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