Role of macrophages in HIV infection and persistence (Q37755250)

22 August 2017

Role of macrophages in HIV infection and persistence (English)

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22 August 2017

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Stephanie Venzke

1

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PubMed ID

20477617

22 August 2017

Oliver T Keppler

series ordinal

2

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PubMed ID

20477617

22 August 2017

language of work or name

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1 July 2006

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Expert Review of Clinical Immunology

22 August 2017

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22 August 2017

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22 August 2017

613-626

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22 August 2017

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Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

22 August 2017

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

HIV-1 dynamics in vivo: implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

The birth of immunology: Metchnikoff, the embryologist

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

The origin and kinetics of mononuclear phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Monocyte and macrophage heterogeneity

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Monocyte production during inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Determination of the origin and nature of brain macrophages and microglial cells in mouse central nervous system, using non-radioactive in situ hybridization and immunoperoxidase techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

HIV-1 receptors and cell tropism

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Macrophages and HIV-1: dangerous liaisons

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Fusion of monocytes and macrophages with HIV-1 correlates with biochemical properties of CXCR4 and CCR5.

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Tissue-resident macrophages are productively infected ex vivo by primary X4 isolates of human immunodeficiency virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Complex determinants in human immunodeficiency virus type 1 envelope gp120 mediate CXCR4-dependent infection of macrophages

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Human immunodeficiency virus type 1 entry into macrophages mediated by macropinocytosis

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Syndecans serve as attachment receptors for human immunodeficiency virus type 1 on macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Involvement of integrin alphavbeta3 in the pathogenesis of human immunodeficiency virus type 1 infection in monocytes.

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Role of complement and Fc receptors in the pathogenesis of HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Secretory Leukocyte Protease Inhibitor Binds to Annexin II, a Cofactor for Macrophage HIV-1 Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Potential role for CD63 in CCR5-mediated human immunodeficiency virus type 1 infection of macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

The kinetics of human immunodeficiency virus reverse transcription are slower in primary human macrophages than in a lymphoid cell line

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Visualization of the intracellular behavior of HIV in living cells

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

The cell cycle independence of HIV infections is not determined by known karyophilic viral elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Nuclear import of HIV-1 intracellular reverse transcription complexes is mediated by importin 7

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Importin 7 may be dispensable for human immunodeficiency virus type 1 and simian immunodeficiency virus infection of primary macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

The inner-nuclear-envelope protein emerin regulates HIV-1 infectivity

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

HIV-1 infection and regulation of Tat function in macrophages

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Regulation of HIV-1 gene transcription: from lymphocytes to microglial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

CCAAT/enhancer binding protein (C/EBP) sites are required for HIV-1 replication in primary macrophages but not CD4(+) T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Plasma membrane rafts play a critical role in HIV-1 assembly and release

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Human macrophages accumulate HIV-1 particles in MHC II compartments

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Infectious HIV-1 assembles in late endosomes in primary macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Productive infection of T cells in lymphoid tissues during primary and early human immunodeficiency virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Macrophage HIV-1 infection and the gastrointestinal tract reservoir

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Viral and host cofactors facilitate HIV-1 replication in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

The role of Langerhans cells in the sexual transmission of HIV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

HIV-1 fitness and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

The contribution of monocyte infection and trafficking to viral persistence, and maintenance of the viral reservoir in HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Amino acid deletions are introduced into the V2 region of gp120 during independent pathogenic simian immunodeficiency virus/HIV chimeric virus (SHIV) infections of rhesus monkeys generating variants that are macrophage tropic

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Macrophage-tropic simian/human immunodeficiency virus chimeras use CXCR4, not CCR5, for infections of rhesus macaque peripheral blood mononuclear cells and alveolar macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Anti-nerve growth factor Ab abrogates macrophage-mediated HIV-1 infection and depletion of CD4+ T lymphocytes in hu-SCID mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

The role of viral coreceptors and enhanced macrophage tropism in human immunodeficiency virus type 1 disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Leishmania infantum enhances human immunodeficiency virus type-1 replication in primary human macrophages through a complex cytokine network

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Macrophages archive HIV-1 virions for dissemination in trans

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Macrophage-dependent apoptosis of CD4+ T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Dressed to kill? A review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Defective phagocytosis by human monocyte/macrophages following HIV-1 infection: underlying mechanisms and modulation by adjunctive cytokine therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Human immunodeficiency virus type 1-induced macrophage gene expression includes the p21 gene, a target for viral regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

The macrophage in HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Mononuclear phagocyte immunity and the neuropathogenesis of HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

The neuropathogenesis of AIDS

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Anti-HIV drug development--an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Relationship between pre-existing viral reservoirs and the re-emergence of plasma viremia after discontinuation of highly active anti-retroviral therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Infection of dendritic cells (DCs), not DC-SIGN-mediated internalization of human immunodeficiency virus, is required for long-term transfer of virus to T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Biphasic decay of latently infected CD4+ T cells in acute human immunodeficiency virus type 1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Predominance of Distinct Viral Genotypes in Brain and Lymph Node Compartments of HIV-1-Infected Individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Compartmentalization of surface envelope glycoprotein of human immunodeficiency virus type 1 during acute and chronic infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Compartmentalization of human immunodeficiency virus type 1 between blood monocytes and CD4+ T cells during infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Persistence of distinct HIV-1 populations in blood monocytes and naive and memory CD4 T cells during prolonged suppressive HAART.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Astrocyte specific viral strains in HIV dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Genetic characterization of rebounding HIV-1 after cessation of highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Antiviral profile of HIV inhibitors in macrophages: implications for therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Long-term survival and virus production in human primary macrophages infected by human immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Blood-brain barrier drug discovery for central nervous system infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

The implications of P-glycoprotein in HIV: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Penetration of enfuvirtide, tenofovir, efavirenz, and protease inhibitors in the genital tract of HIV-1-infected men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

A long-term latent reservoir for HIV-1: discovery and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Latent reservoirs of HIV: obstacles to the eradication of virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Depletion of latent HIV-1 infection in vivo: a proof-of-concept study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Drug-loaded red blood cell-mediated clearance of HIV-1 macrophage reservoir by selective inhibition of STAT1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Selective elimination of HIV-1-infected cells by Env-directed, HIV-1-based virus-like particles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Progress toward a human CD4/CCR5 transgenic rat model for de novo infection by human immunodeficiency virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

A review of gene therapy for haematological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

HIV-1 DNA burden dynamics in CD4 T cells and monocytes in patients undergoing a transient therapy interruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

HIV interaction with endosomes in macrophages and dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

Sexual Transmission and Propagation of SIV and HIV in Resting and Activated CD4+ T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

A CXCR4/CD4 Pseudotype Rhabdovirus That Selectively Infects HIV-1 Envelope Protein-Expressing Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2.4.613

21 January 2018

Identifiers

DOI

10.1586/1744666X.2.4.613

1 reference

22 August 2017

1 reference

PubMed ID

20477617