The role of bHLH genes in ear development and evolution: revisiting a 10-year-old hypothesis (Q37760085)

22 August 2017

1 reference

title

The role of bHLH genes in ear development and evolution: revisiting a 10-year-old hypothesis (English)

1 reference

22 August 2017

1

1 reference

22 August 2017

Daniel F Eberl

2

1 reference

PMCID

3665285

22 August 2017

Kirk W Beisel

series ordinal

3

1 reference

22 August 2017

22 May 2010

1 reference

Cellular and Molecular Life Sciences

22 August 2017

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22 August 2017

67

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22 August 2017

18

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22 August 2017

3089-3099

1 reference

https://scigraph.springernature.com/pub.10.1007/s00018-010-0403-x

22 August 2017

0 references

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22 August 2017

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Context dependence of proneural bHLH proteins

22 August 2017

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22 August 2017

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22 August 2017

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22 August 2017

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22 August 2017

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22 August 2017

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Multiple enhancers contribute to spatial but not temporal complexity in the expression of the proneural gene, amos

22 August 2017

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Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit

22 August 2017

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Sequential roles for Mash1 and Ngn2 in the generation of dorsal spinal cord interneurons.

22 August 2017

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Sox2 is required for sensory organ development in the mammalian inner ear

22 August 2017

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Atoh1 null mice show directed afferent fiber growth to undifferentiated ear sensory epithelia followed by incomplete fiber retention

22 August 2017

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22 August 2017

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Expression of bHLH Transcription Factors NSCL1 and NSCL2 in the Mouse Olfactory System

22 August 2017

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22 August 2017

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Development and evolution of inner ear sensory epithelia and their innervation.

22 August 2017

1 reference

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Proneural genes and the specification of neural cell types

22 August 2017

1 reference

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Neurogenin 1 null mutant ears develop fewer, morphologically normal hair cells in smaller sensory epithelia devoid of innervation

22 August 2017

1 reference

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Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneurons

22 August 2017

1 reference

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NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Developmental evolutionary biology of the vertebrate ear: conserving mechanoelectric transduction and developmental pathways in diverging morphologies

22 August 2017

1 reference

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Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems

22 August 2017

1 reference

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A genetic programme for neuronal connectivity

22 August 2017

1 reference

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cato encodes a basic helix-loop-helix transcription factor implicated in the correct differentiation of Drosophila sense organs

22 August 2017

1 reference

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Math1: an essential gene for the generation of inner ear hair cells

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice.

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Conserved regulation of Math5 and Math1 revealed by Math5-GFP transgenes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

The basic helix-loop-helix transcription factor NeuroD1 facilitates interaction of Sp1 with the secretin gene enhancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Neurod1 regulates survival and formation of connections in mouse ear and brain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Defects in the cerebella of conditional Neurod1 null mice correlate with effective Tg(Atoh1-cre) recombination and granule cell requirements for Neurod1 for differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Specificity of Atonal and Scute bHLH factors: analysis of cognate E box binding sites and the influence of Senseless

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Functional distinctness of closely related transcription factors: a comparison of the Atonal and Amos proneural factors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Evolution of taste and solitary chemoreceptor cell systems

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Spatial and temporal specification of neural fates by transcription factor codes.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Zebrafish atoh1 genes: classic proneural activity in the inner ear and regulation by Fgf and Notch

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Functional redundancy of NSCL-1 and NeuroD during development of the petrosal and vestibulocochlear ganglia.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Molecular signals regulating proliferation of stem and progenitor cells in mouse olfactory epithelium

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

EGF receptor signaling triggers recruitment of Drosophila sense organ precursors by stimulating proneural gene autoregulation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Separable enhancer sequences regulate the expression of the neural bHLH transcription factor neurogenin 1.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Distinct domains within Mash1 and Math1 are required for function in neuronal differentiation versus neuronal cell-type specification.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Bhlhb5 is expressed in the CNS and sensory organs during mouse embryonic development.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Neurogenin1 defines zebrafish cranial sensory ganglia precursors

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Drosophila atonal fully rescues the phenotype of Math1 null mice: new functions evolve in new cellular contexts.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

amos, a proneural gene for Drosophila olfactory sense organs that is regulated by lozenge

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Functional conservation of atonal and Math1 in the CNS and PNS.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Transcriptional regulation of atonal during development of the Drosophila peripheral nervous system.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Clonal analysis of the relationships between mechanosensory cells and the neurons that innervate them in the chicken ear

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3665285

Auditory neurons make stereotyped wiring decisions before maturation of their targets

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20495996

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Myb p75 oncoprotein is expressed in developing otic and epibranchial placodes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20495996

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00018-010-0403-X

1 reference

22 August 2017

1 reference

22 August 2017

1 reference

PMCID

3665285