The expanding universe of cohesin functions: a new genome stability caretaker involved in human disease and cancer. (Q37761724)

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4 February 2020

review article

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title

The expanding universe of cohesin functions: a new genome stability caretaker involved in human disease and cancer (English)

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4 February 2020

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3

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4 February 2020

author name string

Linda Mannini

series ordinal

1

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4 February 2020

Stefania Menga

series ordinal

2

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4 February 2020

publication date

1 June 2010

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4 February 2020

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4 February 2020

volume

31

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4 February 2020

issue

6

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4 February 2020

page(s)

623-630

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Precocious sister chromatid separation (PSCS) in Cornelia de Lange syndrome

4 February 2020

cites work

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The DXS423E gene in Xp11.21 escapes X chromosome inactivation

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Premature chromatid separation is not a useful diagnostic marker for Cornelia de Lange syndrome.

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Mutations in cohesin complex members SMC3 and SMC1A cause a mild variant of cornelia de Lange syndrome with predominant mental retardation

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History of C-patient with SC-Roberts/pseudothalidamide syndrome

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Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase

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NIPBL mutational analysis in 120 individuals with Cornelia de Lange syndrome and evaluation of genotype-phenotype correlations.

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The molecular mechanism underlying Roberts syndrome involves loss of ESCO2 acetyltransferase activity

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Evidence that Loading of Cohesin Onto Chromosomes Involves Opening of Its SMC Hinge

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Chromosomal cohesin forms a ring

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Molecular architecture of SMC proteins and the yeast cohesin complex

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Structure and stability of cohesin's Smc1-kleisin interaction

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Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2.

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Cohesin cleavage by separase required for anaphase and cytokinesis in human cells

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Distinct targets of the Eco1 acetyltransferase modulate cohesion in S phase and in response to DNA damage

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Cohesin-dependent regulation of Runx genes

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Rings, bracelet or snaps: fashionable alternatives for Smc complexes

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A Physical Assay for Sister Chromatid Cohesion In Vitro

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Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion

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Studies of mitotic and centromeric abnormalities in Roberts syndrome: Implications for a defect in the mitotic mechanism

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The Cohesin loading factor NIPBL recruits histone deacetylases to mediate local chromatin modifications

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7 January 2021

The many functions of SMC proteins in chromosome dynamics

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7 January 2021

Multiple organ system defects and transcriptional dysregulation in the Nipbl(+/-) mouse, a model of Cornelia de Lange Syndrome

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7 January 2021

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

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7 January 2021

Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway

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Natural history of aging in Cornelia de Lange syndrome

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The Scc2/Scc4 cohesin loader determines the distribution of cohesin on budding yeast chromosomes.

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Cornelia de Lange syndrome is caused by mutations in NIPBL, the human homolog of Drosophila melanogaster Nipped-B

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Wapl controls the dynamic association of cohesin with chromatin

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Genetic instability in colorectal cancers

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Cohesin relocation from sites of chromosomal loading to places of convergent transcription

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SMC1A expression and mechanism of pathogenicity in probands with X-Linked Cornelia de Lange syndrome

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Cohesin and human disease

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Transcriptional dysregulation in NIPBL and cohesin mutant human cells

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Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts

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7 January 2021

Identification and characterization of SA/Scc3p subunits in the Xenopus and human cohesin complexes

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Regulation of intra-S phase checkpoint by ionizing radiation (IR)-dependent and IR-independent phosphorylation of SMC3.

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Spectrum and consequences of SMC1A mutations: the unexpected involvement of a core component of cohesin in human disease

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Recapitulation of the Roberts syndrome cellular phenotype by inhibition of INCENP, ZWINT-1 and ZW10 genes.

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Oculomotor nerve cavernous angioma in a patient with Roberts syndrome

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7 January 2021

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7 January 2021

RAD21 and KIAA0196 at 8q24 are amplified and overexpressed in prostate cancer

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7 January 2021

Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I.

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7 January 2021

Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates

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7 January 2021

Cornelia de Lange syndrome mutations in SMC1A or SMC3 affect binding to DNA

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7 January 2021

Drosophila nipped-B protein supports sister chromatid cohesion and opposes the stromalin/Scc3 cohesion factor to facilitate long-range activation of the cut gene

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7 January 2021

CTCF physically links cohesin to chromatin

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7 January 2021

Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression

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7 January 2021

Regulation of the Drosophila Enhancer of split and invected-engrailed gene complexes by sister chromatid cohesion proteins

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7 January 2021

Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase

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7 January 2021

Inactivating mutations in ESCO2 cause SC phocomelia and Roberts syndrome: no phenotype-genotype correlation

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7 January 2021

Releasing cohesin from chromosome arms in early mitosis: opposing actions of Wapl-Pds5 and Sgo1

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7 January 2021

Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery

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7 January 2021

Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators

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7 January 2021

Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair.

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7 January 2021

Cloning and characterization of mammalian SMC1 and SMC3 genes and proteins, components of the DNA recombination complexes RC-1.

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Characterization of vertebrate cohesin complexes and their regulation in prophase

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Cohesin acetylation speeds the replication fork

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NIPBL, encoding a homolog of fungal Scc2-type sister chromatid cohesion proteins and fly Nipped-B, is mutated in Cornelia de Lange syndrome

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7 January 2021

Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication

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7 January 2021

Chromosomal domains and escape from X inactivation: comparative X inactivation analysis in mouse and human

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7 January 2021

Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

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7 January 2021

DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain

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7 January 2021

Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion

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7 January 2021

Increased DNA damage sensitivity of Cornelia de Lange syndrome cells: evidence for impaired recombinational repair

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7 January 2021

Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase

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7 January 2021

Cohesin mediates transcriptional insulation by CCCTC-binding factor

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7 January 2021

Rhabdomyosarcoma in Roberts syndrome

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7 January 2021

Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

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7 January 2021

Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression

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7 January 2021

Cohesin subunit SMC1 associates with mitotic microtubules at the spindle pole

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7 January 2021

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

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7 January 2021

Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies

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7 January 2021

Acetylation of Smc3 by Eco1 is required for S phase sister chromatid cohesion in both human and yeast

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7 January 2021

Overexpression of Separase induces aneuploidy and mammary tumorigenesis

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7 January 2021

Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

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7 January 2021