Phosphate homeostasis and the renal-gastrointestinal axis (Q37763810)

22 August 2017

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title

Phosphate homeostasis and the renal-gastrointestinal axis (English)

1 reference

22 August 2017

Joanne Marks

1

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22 August 2017

Edward S Debnam

series ordinal

2

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22 August 2017

Robert J Unwin

series ordinal

3

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22 August 2017

publication date

9 June 2010

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American Journal of Physiology - Renal Physiology

22 August 2017

published in

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22 August 2017

volume

299

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22 August 2017

issue

2

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22 August 2017

page(s)

F285-96

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Association of serum phosphate with vascular and valvular calcification in moderate CKD.

22 August 2017

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21 January 2018

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The renal Na+/phosphate cotransporter NaPi-IIa is internalized via the receptor-mediated endocytic route in response to parathyroid hormone

21 January 2018

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Cloning and characterization of a type III Na-dependent phosphate cotransporter from mouse intestine.

21 January 2018

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Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

SLC34A3 mutations in patients with hereditary hypophosphatemic rickets with hypercalciuria predict a key role for the sodium-phosphate cotransporter NaPi-IIc in maintaining phosphate homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Phosphatonins and the regulation of phosphate homeostasis

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Evidence for a signaling axis by which intestinal phosphate rapidly modulates renal phosphate reabsorption

21 January 2018

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Biological activity of FGF-23 fragments

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Phosphate transport into brush-border membrane vesicles isolated from rat small intestine

21 January 2018

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Regulation of phosphate transport in proximal tubules.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Renal phosphate loss in hereditary and acquired disorders of bone mineralization.

21 January 2018

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The villus gradient of brush border membrane calmodulin and the calcium-independent calmodulin-binding protein parallels that of calcium-accumulating ability

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Ontogeny of intestinal phosphate absorption in rabbits

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Differential regulation of the renal sodium-phosphate cotransporters NaPi-IIa, NaPi-IIc, and PiT-2 in dietary potassium deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Intestinal and renal adaptation to a low-Pi diet of type II NaPi cotransporters in vitamin D receptor- and 1alphaOHase-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Fibroblast growth factor 7: an inhibitor of phosphate transport derived from oncogenic osteomalacia-causing tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

The SLC20 family of proteins: dual functions as sodium-phosphate cotransporters and viral receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Mutations in SLC34A2 cause pulmonary alveolar microlithiasis and are possibly associated with testicular microlithiasis

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

The effects of streptozotocin diabetes on sodium-glucose transporter (SGLT1) expression and function in rat jejunal and ileal villus-attached enterocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Relations of Serum Phosphorus and Calcium Levels to the Incidence of Cardiovascular Disease in the Community

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Microelectrode determination of pH and PCO2 in rat proximal tubule after benzolamide: Evidence for hydrogen ion secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Nicotinamide prevents the development of hyperphosphataemia by suppressing intestinal sodium-dependent phosphate transporter in rats with adenine-induced renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Initial FGF23-mediated signaling occurs in the distal convoluted tubule

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Proximal tubular handling of phosphate: A molecular perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Electrogenic kinetics of a mammalian intestinal type IIb Na(+)/P(i) cotransporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Regulation of rat intestinal Na-dependent phosphate transporters by dietary phosphate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

The assay of 1alpha,25-dihydroxyvitamin D3: physiologic and pathologic modulation of circulating hormone levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Characterization of a murine type II sodium-phosphate cotransporter expressed in mammalian small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Role of the vitamin D receptor in FGF23 action on phosphate metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

A novel missense mutation in SLC34A3 that causes hereditary hypophosphatemic rickets with hypercalciuria in humans identifies threonine 137 as an important determinant of sodium-phosphate cotransport in NaPi-IIc

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Nicotinamide inhibits sodium-dependent phosphate cotransport activity in rat small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Recent advances in the renal-skeletal-gut axis that controls phosphate homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Severely reduced production of klotho in human chronic renal failure kidney.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Regulation of fibroblast growth factor-23 signaling by klotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

NPT2a gene variation in calcium nephrolithiasis with renal phosphate leak.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Expression of the rat renal PiT-2 phosphate transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Management of disturbances of calcium and phosphate metabolism in chronic renal insufficiency, with emphasis on the control of hyperphosphataemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Safety of new phosphate binders for chronic renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Phosphate binders for control of phosphate retention in chronic renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Use of phosphonoformic acid to induce phosphaturia in chronic renal failure in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

A loss-of-function mutation in NaPi-IIa and renal Fanconi's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Matrix extracellular phosphoglycoprotein inhibits phosphate transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Inhibitory effect of JTP-59557, a new triazole derivative, on intestinal phosphate transport in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Inhibition of intestinal sodium-dependent inorganic phosphate transport by fibroblast growth factor 23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

New aspect of renal phosphate reabsorption: the type IIc sodium-dependent phosphate transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

The sodium phosphate cotransporter family SLC34

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Regulation of Na/Pi transporter in the proximal tubule

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Proximal tubular phosphate reabsorption: molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Molecular mechanisms in proximal tubular and small intestinal phosphate reabsorption (plenary lecture).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Mechanisms of renal phosphate loss in liver resection-associated hypophosphatemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Inactivation of klotho function induces hyperphosphatemia even in presence of high serum fibroblast growth factor 23 levels in a genetically engineered hypophosphatemic (Hyp) mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Renal phosphaturia during metabolic acidosis revisited: molecular mechanisms for decreased renal phosphate reabsorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Renal expression of SIBLING proteins and their partner matrix metalloproteinases (MMPs)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

A patient with hypophosphatemia, a femoral fracture, and recurrent kidney stones: report of a novel mutation in SLC34A3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

A phosphorylated phloretin derivative. Synthesis and effect on intestinal Na(+)-dependent phosphate absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Inhibition of human intestinal brush border membrane vesicle Na+-dependent phosphate uptake by phosphophloretin derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Phosphophloretin sensitivity of rabbit renal NaPi-IIa and NaPi-Ia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Effect of 2'-phosphophloretin on renal function in chronic renal failure rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Lanthanum: a safe phosphate binder

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Nephrolithiasis and osteoporosis associated with hypophosphatemia caused by mutations in the type 2a sodium-phosphate cotransporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Latest findings in phosphate homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Regulation of intestinal phosphate transport. I. Segmental expression and adaptation to low-P(i) diet of the type IIb Na(+)-P(i) cotransporter in mouse small intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Expression of renal and intestinal Na/Pi cotransporters in the absence of GABARAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

The wrickkened pathways of FGF23, MEPE and PHEX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

MEPE has the properties of an osteoblastic phosphatonin and minhibin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Intestinal npt2b plays a major role in phosphate absorption and homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Human fibroblast growth factor-23 mutants suppress Na+-dependent phosphate co-transport activity and 1alpha,25-dihydroxyvitamin D3 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Circulating FGF-23 is regulated by 1alpha,25-dihydroxyvitamin D3 and phosphorus in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Intestinal Na-P(i) cotransporter adaptation to dietary P(i) content in vitamin D receptor null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Effect of hydrolysis-resistant FGF23-R179Q on dietary phosphate regulation of the renal type-II Na/Pi transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Npt2a and Npt2c in mice play distinct and synergistic roles in inorganic phosphate metabolism and skeletal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Type IIc sodium-dependent phosphate transporter regulates calcium metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Internalization of renal type IIc Na-Pi cotransporter in response to a high-phosphate diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Regulation of phosphate homeostasis by the phosphatonins and other novel mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Possible involvement of circulating fibroblast growth factor 23 in the development of secondary hyperparathyroidism associated with renal insufficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Dietary phosphorus acutely impairs endothelial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

beta-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Regulation of intestinal phosphate transport. II. Metabolic acidosis stimulates Na(+)-dependent phosphate absorption and expression of the Na(+)-P(i) cotransporter NaPi-IIb in small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Nicotinamide suppresses hyperphosphatemia in hemodialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Differential effects of Npt2a gene ablation and X-linked Hyp mutation on renal expression of Npt2c

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Magnesium stimulates renal phosphate reabsorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Phosphaturic action of fibroblast growth factor 23 in Npt2 null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Interactions of the growth-related, type IIc renal sodium/phosphate cotransporter with PDZ proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

The Na+-Pi cotransporter PiT-2 (SLC20A2) is expressed in the apical membrane of rat renal proximal tubules and regulated by dietary Pi

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Role of rat sodium/phosphate cotransporters in the cell membrane transport of arsenate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Compensatory regulation of the sodium/phosphate cotransporters NaPi-IIc (SCL34A3) and Pit-2 (SLC20A2) during Pi deprivation and acidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Phosphate transporters: a tale of two solute carrier families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Functional characterization of two naturally occurring mutations in the human sodium-phosphate cotransporter type IIa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

The roles of specific genes implicated as circulating factors involved in normal and disordered phosphate homeostasis: frizzled related protein-4, matrix extracellular phosphoglycoprotein, and fibroblast growth factor 23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Age-dependent regulation of rat intestinal type IIb sodium-phosphate cotransporter by 1,25-(OH)(2) vitamin D(3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Regulation of the human sodium-phosphate cotransporter NaP(i)-IIb gene promoter by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

Regulation of intestinal NaPi-IIb cotransporter gene expression by estrogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00508.2009

10.1152/AJPRENAL.00508.2009

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference