Human testicular insulin-like factor 3: in relation to development, reproductive hormones and andrological disorders (Q37765316)

22 August 2017

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title

Human testicular insulin-like factor 3: in relation to development, reproductive hormones and andrological disorders (English)

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22 August 2017

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K Bay

1

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22 August 2017

A-M Andersson

series ordinal

2

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22 August 2017

publication date

1 April 2011

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International Journal of Andrology

22 August 2017

published in

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22 August 2017

volume

34

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22 August 2017

issue

2

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22 August 2017

page(s)

97-109

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The overexpression of the insl3 in female mice causes descent of the ovaries

22 August 2017

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Insulin-like factor 3 serum levels in 135 normal men and 85 men with testicular disorders: relationship to the luteinizing hormone-testosterone axis

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Lysosomal acid hydrolases of the cathepsin family are novel targets of INSL3 in human thyroid carcinoma cells

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Difference in prevalence of congenital cryptorchidism in infants between two Nordic countries.

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Evidence for decreasing quality of semen during past 50 years

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Analogs of insulin-like peptide 3 (INSL3) B-chain are LGR8 antagonists in vitro and in vivo.

21 January 2018

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Endogenous estrogens inhibit mouse fetal Leydig cell development via estrogen receptor alpha

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No association between T222P/LGR8 mutation and cryptorchidism in the Moroccan population

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Involvement of insulin-like factor 3 (Insl3) in diethylstilbestrol-induced cryptorchidism.

21 January 2018

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Peripheral insulin-like factor 3 concentrations are reduced in men with type 2 diabetes mellitus: effect of glycemic control and visceral adiposity on Leydig cell function

21 January 2018

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The INSL3-LGR8/GREAT ligand-receptor pair in human cryptorchidism

21 January 2018

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Mutations in the insulin-like factor 3 receptor are associated with osteoporosis

21 January 2018

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Relaxin family peptide receptors Rxfp1 and Rxfp2: mapping of the mRNA and protein distribution in the reproductive tract of the male rat.

21 January 2018

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A novel circulating hormone of testis origin in humans

21 January 2018

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Role of hormones, genes, and environment in human cryptorchidism

21 January 2018

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Insulin-like factor 3 as a marker of testicular function in obese men.

21 January 2018

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Leucine-rich repeat-containing G-protein-coupled receptor 8 in mature glomeruli of developing and adult rat kidney and inhibition by insulin-like peptide-3 of glomerular cell proliferation

21 January 2018

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Insulin-like factor 3: a new circulating hormone related to luteinizing hormone-dependent ovarian hyperandrogenism in the polycystic ovary syndrome

21 January 2018

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Mutations of the GREAT gene cause cryptorchidism

21 January 2018

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Cellular localization of human relaxin-like factor in the cyclic endometrium and placenta

21 January 2018

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Seasonal expression of INSL3 and Lgr8/Insl3 receptor transcripts indicates variable differentiation of Leydig cells in the roe deer testis

21 January 2018

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Activation of orphan receptors by the hormone relaxin

21 January 2018

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Abnormalities of testicular descent

21 January 2018

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Anatomical and functional aspects of testicular descent and cryptorchidism

21 January 2018

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Evidence of deteriorating semen quality in the United Kingdom: birth cohort study in 577 men in Scotland over 11 years

21 January 2018

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Relaxin-like factor: a highly specific and constitutive new marker for Leydig cells in the human testis

21 January 2018

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21 January 2018

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Paracrine regulation of mammalian oocyte maturation and male germ cell survival

21 January 2018

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Molecular and genetic regulation of testis descent and external genitalia development

21 January 2018

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Male pseudohermaphroditism due to a homozygous missense mutation of the luteinizing hormone receptor gene

21 January 2018

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The role of insulin 3, testosterone, Müllerian inhibiting substance and relaxin in rat gubernacular growth

21 January 2018

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INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent

21 January 2018

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Antagonistic effects of testosterone and the endocrine disruptor mono-(2-ethylhexyl) phthalate on INSL3 transcription in Leydig cells

21 January 2018

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Estradiol represses insulin-like 3 expression and promoter activity in MA-10 Leydig cells

21 January 2018

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Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate

21 January 2018

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Cryptorchidism in mice mutant for Insl3

21 January 2018

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A molecular basis for estrogen-induced cryptorchidism.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2605.2010.01074.X

Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimester

21 January 2018

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Testosterone replacement therapy induces spermatogenesis and partially restores fertility in luteinizing hormone receptor knockout mice

21 January 2018

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Origin of INSL3-mediated testicular descent in therian mammals

21 January 2018

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Relaxin physiology in the female reproductive tract during pregnancy

21 January 2018

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International trends in rates of hypospadias and cryptorchidism

21 January 2018

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Maternal and paternal risk factors for cryptorchidism and hypospadias: a case-control study in newborn boys

21 January 2018

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Ultrastructural evidence of mature Leydig cells and Leydig cell regression in the neonatal human testis.

21 January 2018

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The triphasic nature of Leydig cell development in humans, and comments on nomenclature

21 January 2018

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Development and regulation of growth and differentiated function in human and subhuman primate fetal gonads

21 January 2018

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The orphan nuclear receptor NR4A1 regulates insulin-like 3 gene transcription in Leydig cells

21 January 2018

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Constitutive regulation of the Insl3 gene in rat Leydig cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2605.2010.01074.X

Leucine-rich repeat-containing G-protein-coupled receptor 8 in the rat brain: Enrichment in thalamic neurons and their efferent projections

21 January 2018

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Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects

21 January 2018

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Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects

21 January 2018

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The human Leydig insulin-like (hLEY I-L) gene is expressed in the corpus luteum and trophoblast

21 January 2018

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Transabdominal testicular descent is disrupted in mice with deletion of insulinlike factor 3 receptor

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2605.2010.01074.X

Trends in the incidence of cryptorchidism and hypospadias, and methodological limitations of registry-based data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2605.2010.01074.X

Serum insulin-like factor 3 levels during puberty in healthy boys and boys with Klinefelter syndrome.

21 January 2018

1 reference

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Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis

21 January 2018

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Pituitary-Gonadal Relations in Infancy. I. Patterns of Serum Gonadotropin Concentrations from Birth to Four Years of Age in Man and Chimpanzee

21 January 2018

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The role of RXFP2 in mediating androgen-induced inguinoscrotal testis descent in LH receptor knockout mice

21 January 2018

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Mouse Leydig insulin-like (Ley I-L) gene: structure and expression during testis and ovary development

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2605.2010.01074.X

Transcription of the Leydig insulin-like gene is mediated by steroidogenic factor-1.

21 January 2018

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Targeted disruption of the Insl3 gene causes bilateral cryptorchidism

21 January 2018

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Elevated End-of-Treatment Serum INSL3 Is Associated With Failure to Completely Suppress Spermatogenesis in Men Receiving Male Hormonal Contraception

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2605.2010.01074.X

Insulin-Like Factor 3: A Novel Circulating Hormone of Testicular Origin in Humans

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2605.2010.01074.X

Changes in Serum Insulin-Like Factor 3 during Normal Male Puberty

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2605.2010.01074.X

The origins and time of appearance of focal testicular dysgenesis in an animal model of testicular dysgenesis syndrome: evidence for delayed testis development?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2605.2010.01074.X

10.1111/J.1365-2605.2010.01074.X

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference