Use of metformin in the treatment of polycystic ovary syndrome (Q37769526)

22 August 2017

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title

Use of metformin in the treatment of polycystic ovary syndrome (English)

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polycystic ovary syndrome

22 August 2017

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Alessandro D Genazzani

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Alessandro D Genazzani

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1

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author name string

Federica Ricchieri

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2

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PubMed ID

20597621

22 August 2017

Chiara Lanzoni

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3

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22 August 2017

1 July 2010

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22 August 2017

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22 August 2017

6

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22 August 2017

4

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22 August 2017

577-593

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Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy

22 August 2017

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Genetic and environmental aspect of polycystic ovary syndrome

21 January 2018

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Polycystic ovaries--a common finding in normal women

21 January 2018

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Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

21 January 2018

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Evidence-based and potential benefits of metformin in the polycystic ovary syndrome: a comprehensive review

21 January 2018

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Insulin-sensitizing agents and reproductive function in polycystic ovary syndrome patients

21 January 2018

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The role of genes in the polycystic ovary syndrome: predisposition and mechanisms

21 January 2018

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Neuroendocrine dysfunction in PCOS: a critique of recent reviews.

21 January 2018

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Neuromodulation in polycystic ovary syndrome

21 January 2018

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Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome

21 January 2018

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Pituitary-ovarian responses to nafarelin testing in the polycystic ovary syndrome

21 January 2018

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Polycystic ovary syndrome and the risk of gynaecological cancer: a systematic review

21 January 2018

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Relationship of androgenic activity to splanchnic insulin metabolism and peripheral glucose utilization in premenopausal women.

21 January 2018

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Effect of weight loss and antiandrogenic therapy on sex hormone blood levels and insulin resistance in obese patients with polycystic ovaries

21 January 2018

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Lipoprotein lipid concentrations and cardiovascular risk in women with polycystic ovary syndrome

21 January 2018

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Cardiovascular actions of insulin

21 January 2018

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Postmenopausal women with a history of irregular menses and elevated androgen measurements at high risk for worsening cardiovascular event-free survival: results from the National Institutes of Health--National Heart, Lung, and Blood Institute spons

21 January 2018

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Cardiovascular risk and events in polycystic ovary syndrome

21 January 2018

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21 January 2018

The metabolic syndrome

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Cardiovascular disease in women with polycystic ovary syndrome at long-term follow-up: a retrospective cohort study

21 January 2018

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Screening women with polycystic ovary syndrome for metabolic syndrome

21 January 2018

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Incidence and treatment of metabolic syndrome in newly referred women with confirmed polycystic ovarian syndrome

21 January 2018

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Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome

21 January 2018

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Carotid atherosclerosis in women with polycystic ovary syndrome: initial results from a case-control study.

21 January 2018

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Endothelial control of vascular tone in large and small coronary arteries

21 January 2018

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Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease

21 January 2018

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Polycystic ovary syndrome and cardiovascular disease: a premature association?

21 January 2018

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Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome.

21 January 2018

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Uterine effects of metformin administration in anovulatory women with polycystic ovary syndrome

21 January 2018

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Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians

21 January 2018

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Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome

21 January 2018

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Prevalence of insulin resistance in the polycystic ovary syndrome using the homeostasis model assessment

21 January 2018

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Increased Luteinizing Hormone Secretion in Women with Polycystic Ovary Syndrome Is Unaltered by Prolonged Insulin Infusion

21 January 2018

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Metformin administration modulates and restores luteinizing hormone spontaneous episodic secretion and ovarian function in nonobese patients with polycystic ovary syndrome

21 January 2018

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Insulin sensitizing drugs for weight loss in women of reproductive age who are overweight or obese: systematic review and meta-analysis.

21 January 2018

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21 January 2018

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Metabolic effects of metformin in non-insulin-dependent diabetes mellitus

21 January 2018

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Effects of metformin on adrenal steroidogenesis in women with polycystic ovary syndrome

21 January 2018

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Clinical review: Insulin sensitizers for the treatment of hirsutism: a systematic review and metaanalyses of randomized controlled trials

21 January 2018

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Interactions of the hormones leptin, ghrelin, adiponectin, resistin, and PYY3-36 with the reproductive system

21 January 2018

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21 January 2018

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Insulin sensitivity after metformin suspension in normal-weight women with polycystic ovary syndrome

21 January 2018

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Strategies for the use of insulin-sensitizing drugs to treat infertility in women with polycystic ovary syndrome

21 January 2018

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Metformin for the treatment of the polycystic ovary syndrome

21 January 2018

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Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome

21 January 2018

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Prospective parallel randomized, double-blind, double-dummy controlled clinical trial comparing clomiphene citrate and metformin as the first-line treatment for ovulation induction in nonobese anovulatory women with polycystic ovary syndrome

21 January 2018

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Comparison of clomiphene citrate, metformin, or the combination of both for first-line ovulation induction, achievement of pregnancy, and live birth in Asian women with polycystic ovary syndrome: a randomized controlled trial.

21 January 2018

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Clomiphene, Metformin, or Both for Infertility in the Polycystic Ovary Syndrome

21 January 2018

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Efficacy predictors for metformin and clomiphene citrate treatment in anovulatory infertile patients with polycystic ovary syndrome

21 January 2018

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Meta-analysis: metformin treatment in persons at risk for diabetes mellitus

21 January 2018

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The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial

21 January 2018

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Predictors of ovarian response: progress towards individualized treatment in ovulation induction and ovarian stimulation

21 January 2018

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Metformin improves polycystic ovary syndrome symptoms irrespective of pre-treatment insulin resistance

21 January 2018

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The effects of rosiglitazone and metformin on insulin resistance and serum androgen levels in obese and lean patients with polycystic ovary syndrome

21 January 2018

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Phenotypic spectrum of polycystic ovary syndrome: clinical and biochemical characterization of the three major clinical subgroups

21 January 2018

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Metformin to restore normal menses in oligo-amenorrheic teenage girls with polycystic ovary syndrome (PCOS).

21 January 2018

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Sensitization to insulin induces ovulation in nonobese adolescents with anovulatory hyperandrogenism.

21 January 2018

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Metformin versus ethinyl estradiol-cyproterone acetate in the treatment of nonobese women with polycystic ovary syndrome: a randomized study

21 January 2018

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Fecundability and spontaneous abortions in women with self-reported oligo-amenorrhea and/or hirsutism: Northern Finland Birth Cohort 1966 Study

21 January 2018

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Effect of clomifene citrate plus metformin and clomifene citrate plus placebo on induction of ovulation in women with newly diagnosed polycystic ovary syndrome: randomised double blind clinical trial

21 January 2018

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Impaired insulin-dependent glucose metabolism in granulosa-lutein cells from anovulatory women with polycystic ovaries

21 January 2018

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Two weeks of metformin improves clomiphene citrate-induced ovulation and metabolic profiles in women with polycystic ovary syndrome

21 January 2018

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Ultra-short metformin pretreatment for clomiphene citrate-resistant polycystic ovary syndrome

21 January 2018

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The impact of obesity on reproduction in women with polycystic ovary syndrome

21 January 2018

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Bodyweight changes associated with antihyperglycaemic agents in type 2 diabetes mellitus

21 January 2018

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AMP-activated protein kinase mediates glucocorticoid-induced metabolic changes: a novel mechanism in Cushing's syndrome

21 January 2018

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Androgens and coronary artery disease

21 January 2018

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Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group

21 January 2018

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The impact of glucose lowering treatment on long-term prognosis in patients with type 2 diabetes and myocardial infarction: a report from the DIGAMI 2 trial.

21 January 2018

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Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling

21 January 2018

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Combined lifestyle modification and metformin in obese patients with polycystic ovary syndrome. A randomized, placebo-controlled, double-blind multicentre study

21 January 2018

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Miscarriage rates following in-vitro fertilization are increased in women with polycystic ovaries and reduced by pituitary desensitization with buserelin.

21 January 2018

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Influence of past reproductive performance on risk of spontaneous abortion

21 January 2018

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Continuing metformin throughout pregnancy in women with polycystic ovary syndrome appears to safely reduce first-trimester spontaneous abortion: a pilot study

21 January 2018

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A meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome

21 January 2018

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Should we continue or stop insulin sensitizing drugs during pregnancy?

21 January 2018

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Metformin during pregnancy reduces insulin, insulin resistance, insulin secretion, weight, testosterone and development of gestational diabetes: prospective longitudinal assessment of women with polycystic ovary syndrome from preconception throughou

21 January 2018

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Metformin reduces pregnancy complications without affecting androgen levels in pregnant polycystic ovary syndrome women: results of a randomized study

21 January 2018

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Clomiphene citrate, metformin or both as first-step approach in treating anovulatory infertility in patients with polycystic ovary syndrome (PCOS): a systematic review of head-to-head randomized controlled studies and meta-analysis

21 January 2018

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Effect of preconceptional metformin on abortion risk in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials

21 January 2018

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Pregnancy outcome after first-trimester exposure to metformin: a meta-analysis

21 January 2018

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Growth, motor, and social development in breast- and formula-fed infants of metformin-treated women with polycystic ovary syndrome.

21 January 2018

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A systematic review of the reproductive system effects of metformin in patients with polycystic ovary syndrome

21 January 2018

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Metformin in polycystic ovary syndrome: systematic review and meta-analysis

21 January 2018

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21 January 2018

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Risk of depression and other mental health disorders in women with polycystic ovary syndrome: a longitudinal study.

21 January 2018

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Clinical and psychological correlates of quality-of-life in polycystic ovary syndrome

21 January 2018

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Quality of life, psychosocial well-being, and sexual satisfaction in women with polycystic ovary syndrome.

21 January 2018

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Increased risk of depressive disorders in women with polycystic ovary syndrome.

21 January 2018

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21 January 2018

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Mood and sexual function in polycystic ovary syndrome

21 January 2018

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Metformin treatment of polycystic ovary syndrome improves health-related quality-of-life, emotional distress and sexuality

21 January 2018

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Neurosteroids Biosynthesis and function.

21 January 2018

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Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain

21 January 2018

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In vivo secretion of 3 alpha-hydroxy-5 alpha-pregnan-20-one, a potent anaesthetic steroid, by the adrenal gland of the rat.

21 January 2018

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Neurosteroids: a new brain function?

21 January 2018

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Neurosteroid metabolism. 7 alpha-Hydroxylation of dehydroepiandrosterone and pregnenolone by rat brain microsomes

21 January 2018

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Time-dependent changes in rat brain neuroactive steroid concentrations and GABAA receptor function after acute stress.

21 January 2018

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The effects of inhibitors of GABAergic transmission and stress on brain and plasma allopregnanolone concentrations

21 January 2018

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Allopregnanolone concentration in hippocampus of prepubertal rats and female rats throughout estrous cycle.

21 January 2018

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Evidence for a role for the neurosteroid allopregnanolone in the modulation of reproductive function in female rats.

21 January 2018

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Neurosteroids: endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance

21 January 2018

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Non-genomic and genomic effects of steroids on neural activity

21 January 2018

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Progesterone as a neurosteroid: actions within the nervous system.

21 January 2018

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Pulsatile secretory characteristics of allopregnanolone, a neuroactive steroid, during the menstrual cycle and in amenorrheic subjects

21 January 2018

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Metformin administration modulates neurosteroids secretion in non-obese amenorrhoic patients with polycystic ovary syndrome

21 January 2018

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Metformin administration is more effective when non-obese patients with polycystic ovary syndrome show both hyperandrogenism and hyperinsulinemia

21 January 2018

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Reduced Expression of Nuclear-Encoded Genes Involved in Mitochondrial Oxidative Metabolism in Skeletal Muscle of Insulin-Resistant Women With Polycystic Ovary Syndrome

21 January 2018

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Low sex hormone-binding globulin is associated with low high-density lipoprotein cholesterol and metabolic syndrome in women with PCOS

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/WHE.10.43

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22 August 2017

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PubMed ID

20597621