The 11beta-hydroxysteroid dehydrogenase enzymes--arbiters of the effects of glucocorticoids in synovium and bone (Q37773096)

22 August 2017

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title

The 11beta-hydroxysteroid dehydrogenase enzymes--arbiters of the effects of glucocorticoids in synovium and bone (English)

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22 August 2017

2

Rowan Hardy

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22 August 2017

Karim Raza

1

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PubMed ID

20634231

22 August 2017

Mark S Cooper

series ordinal

3

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22 August 2017

15 July 2010

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22 August 2017

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22 August 2017

49

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22 August 2017

2016-2023

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22 August 2017

11

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Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats

22 August 2017

1 reference

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A defect in cortisol production in rheumatoid arthritis: why are we still looking?

21 January 2018

1 reference

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Inadequately low serum levels of steroid hormones in relation to interleukin-6 and tumor necrosis factor in untreated patients with early rheumatoid arthritis and reactive arthritis

21 January 2018

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Corticosteroid insufficiency in acutely ill patients

21 January 2018

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Adrenal insufficiency in critical illness

21 January 2018

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Antiinflammatory action of glucocorticoids--new mechanisms for old drugs

21 January 2018

1 reference

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11Beta-hydroxysteroid dehydrogenase type 1 and its role in the hypothalamus-pituitary-adrenal axis, metabolic syndrome, and inflammation

21 January 2018

1 reference

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Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated

21 January 2018

1 reference

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11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress

21 January 2018

1 reference

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11beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKEQ212

Catabolism and interconversion of cortisol and cortisone in human synovial tissue in vitro

21 January 2018

1 reference

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Reduced capacity for the reactivation of glucocorticoids in rheumatoid arthritis synovial cells: possible role of the sympathetic nervous system?

21 January 2018

1 reference

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Local and systemic glucocorticoid metabolism in inflammatory arthritis

21 January 2018

1 reference

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A gene expression signature for recent onset rheumatoid arthritis in peripheral blood mononuclear cells

21 January 2018

1 reference

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Identification of genes modulated in rheumatoid arthritis using complementary DNA microarray analysis of lymphoblastoid B cell lines from disease-discordant monozygotic twins

21 January 2018

1 reference

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Differential expression, function and response to inflammatory stimuli of 11beta-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation

21 January 2018

1 reference

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Synergistic induction of local glucocorticoid generation by inflammatory cytokines and glucocorticoids: implications for inflammation associated bone loss.

21 January 2018

1 reference

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Clinical comparison of the newer anti-inflammatory corticosteroids

21 January 2018

1 reference

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Prereceptor regulation of glucocorticoid action by 11beta-hydroxysteroid dehydrogenase: a novel determinant of cell proliferation

21 January 2018

1 reference

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11beta-Hydroxysteroid dehydrogenase expression and glucocorticoid synthesis are directed by a molecular switch during osteoblast differentiation.

21 January 2018

1 reference

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Modulation of 11beta-hydroxysteroid dehydrogenase isozymes by proinflammatory cytokines in osteoblasts: an autocrine switch from glucocorticoid inactivation to activation

21 January 2018

1 reference

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Osteoblastic 11beta-hydroxysteroid dehydrogenase type 1 activity increases with age and glucocorticoid exposure

21 January 2018

1 reference

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Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKEQ212

Circulating cortisone levels are associated with biochemical markers of bone formation and lumbar spine BMD: the Hertfordshire Cohort Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FRHEUMATOLOGY%2FKEQ212

11beta-hydroxysteroid dehydrogenase type 1 activity predicts the effects of glucocorticoids on bone

21 January 2018

1 reference

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Transgenic disruption of glucocorticoid signaling in mature osteoblasts and osteocytes attenuates K/BxN mouse serum-induced arthritis in vivo.

21 January 2018

1 reference

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11beta-hydroxysteroid dehydrogenase type 1 inhibitors: a review of recent patents

21 January 2018

1 reference

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10.1093/RHEUMATOLOGY/KEQ212

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference

PubMed ID

20634231