Cell therapy for heart failure: the need for a new therapeutic strategy (Q37776514)

23 August 2017

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title

Cell therapy for heart failure: the need for a new therapeutic strategy (English)

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23 August 2017

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Christopher M O'Connor

series ordinal

2

object named as

Christopher M O'Connor

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23 August 2017

Thomas J Povsic

1

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23 August 2017

1 August 2010

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Expert Review of Cardiovascular Therapy

23 August 2017

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23 August 2017

8

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23 August 2017

1107-1126

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23 August 2017

8

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Heart Disease and Stroke Statistics--2010 Update: A Report From the American Heart Association

23 August 2017

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The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications

21 January 2018

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Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators

21 January 2018

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Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure

21 January 2018

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Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure. MOCHA Investigators.

21 January 2018

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Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)

21 January 2018

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Effect of carvedilol on survival in severe chronic heart failure

21 January 2018

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Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on morbidity and mortality in chronic heart failure. ATLAS Study Group.

21 January 2018

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Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction

21 January 2018

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The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators

21 January 2018

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A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure

21 January 2018

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Long-term effects of darusentan on left-ventricular remodelling and clinical outcomes in the EndothelinA Receptor Antagonist Trial in Heart Failure (EARTH): randomised, double-blind, placebo-controlled trial

21 January 2018

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Chronic mechanical circulatory support for inotrope-dependent heart failure patients who are not transplant candidates: results of the INTrEPID Trial

21 January 2018

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Left ventricular assist device and drug therapy for the reversal of heart failure

21 January 2018

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Cardiac resynchronization in chronic heart failure

21 January 2018

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Effects of cardiac resynchronization on disease progression in patients with left ventricular systolic dysfunction, an indication for an implantable cardioverter-defibrillator, and mildly symptomatic chronic heart failure.

21 January 2018

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Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure

21 January 2018

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The effect of cardiac resynchronization on morbidity and mortality in heart failure

21 January 2018

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Stem cells as a source of regenerative cardiomyocytes

21 January 2018

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Embryonic stem cell lines derived from human blastocysts

21 January 2018

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Myocardial homing of nonmobilized peripheral-blood CD34+ cells after intracoronary injection.

21 January 2018

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Monitoring of bone marrow cell homing into the infarcted human myocardium

21 January 2018

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Images in cardiovascular medicine. Early tissue distribution of bone marrow mononuclear cells after transcoronary transplantation in a patient with acute myocardial infarction.

21 January 2018

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Pilot trial on determinants of progenitor cell recruitment to the infarcted human myocardium.

21 January 2018

1 reference

Evidence that intracoronary-injected CD133+ peripheral blood progenitor cells home to the myocardium in chronic postinfarction heart failure.

21 January 2018

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A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction

21 January 2018

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A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction.

21 January 2018

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Bioengineered cardiac cell sheet grafts have intrinsic angiogenic potential.

21 January 2018

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Fibroblast sheets co-cultured with endothelial progenitor cells improve cardiac function of infarcted hearts.

21 January 2018

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Cell sheet engineering for heart tissue repair

21 January 2018

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Cardiac tissue engineering using stem cells

21 January 2018

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Transcoronary transplantation of progenitor cells after myocardial infarction

21 January 2018

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Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI)

21 January 2018

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Infarct remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCARE-AMI): mechanistic insights from serial contrast-enhanced magnetic resonance imaging

21 January 2018

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Transplantation of progenitor cells after reperfused acute myocardial infarction: evaluation of perfusion and myocardial viability with FDG-PET and thallium SPECT.

21 January 2018

1 reference

Efficacy of emergent transcatheter transplantation of stem cells for treatment of acute myocardial infarction (TCT-STAMI).

21 January 2018

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Effects of intracoronary injection of mononuclear bone marrow cells on left ventricular function, arrhythmia risk profile, and restenosis after thrombolytic therapy of acute myocardial infarction.

21 January 2018

1 reference

Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomised cl

21 January 2018

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Cells expressing early cardiac markers reside in the bone marrow and are mobilized into the peripheral blood after myocardial infarction

21 January 2018

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Atorvastatin reduces tissue factor expression in adipose tissue of atherosclerotic rabbits.

21 January 2018

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Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction

21 January 2018

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Autologous transplantation of mononuclear bone marrow cells in patients with acute myocardial infarction: the effect of the dose of transplanted cells on myocardial function.

21 January 2018

1 reference

Intracoronary Bone Marrow–Derived Progenitor Cells in Acute Myocardial Infarction

21 January 2018

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Improved clinical outcome after intracoronary administration of bone-marrow-derived progenitor cells in acute myocardial infarction: final 1-year results of the REPAIR-AMI trial

21 January 2018

1 reference

Regeneration of human infarcted heart muscle by intracoronary autologous bone marrow cell transplantation in chronic coronary artery disease: the IACT Study.

21 January 2018

1 reference

Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans

21 January 2018

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Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial

21 January 2018

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The BALANCE Study: clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial infarction

21 January 2018

1 reference

Is the placebo powerless? An analysis of clinical trials comparing placebo with no treatment

21 January 2018

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Do medical devices have enhanced placebo effects?

21 January 2018

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Recovery of regional but not global contractile function by the direct intramyocardial autologous bone marrow transplantation: results from a randomized controlled clinical trial.

21 January 2018

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Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial

21 January 2018

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Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis

21 January 2018

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Intracoronary infusion of autologous bone marrow cells and left ventricular function after acute myocardial infarction: a meta-analysis

21 January 2018

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Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a collaborative systematic review and meta-analysis of controlled clinical trials.

21 January 2018

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Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant diseases

21 January 2018

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Cell isolation procedures matter: a comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction

21 January 2018

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Bringing cardiovascular cell-based therapy to clinical application: perspectives based on a National Heart, Lung, and Blood Institute Cell Therapy Working Group meeting

21 January 2018

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Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure

21 January 2018

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Transcoronary transplantation of functionally competent BMCs is associated with a decrease in natriuretic peptide serum levels and improved survival of patients with chronic postinfarction heart failure: results of the TOPCARE-CHD Registry.

21 January 2018

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Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease

21 January 2018

1 reference

Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction

21 January 2018

1 reference

Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells.

21 January 2018

1 reference

Rationale and design for TIME: A phase II, randomized, double-blind, placebo-controlled pilot trial evaluating the safety and effect of timing of administration of bone marrow mononuclear cells after acute myocardial infarction

21 January 2018

1 reference

Intracoronary administration of autologous bone marrow mononuclear cells after induction of short ischemia is safe and may improve hibernation and ischemia in patients with ischemic cardiomyopathy

21 January 2018

1 reference

Catheter-based autologous bone marrow myocardial injection in no-option patients with advanced coronary artery disease: a feasibility study

21 January 2018

1 reference

Local implantation of autologous bone marrow cells for therapeutic angiogenesis in patients with ischemic heart disease: clinical trial and preliminary results

21 January 2018

1 reference

Intramyocardial transplantation of autologous CD34+ stem cells for intractable angina: a phase I/IIa double-blind, randomized controlled trial.

21 January 2018

1 reference

Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation

21 January 2018

1 reference

Antianginal efficacy of ranolazine when added to treatment with amlodipine: the ERICA (Efficacy of Ranolazine in Chronic Angina) trial

21 January 2018

1 reference

Effect of intracoronary transplantation of autologous bone marrow-derived mononuclear cells on outcomes of patients with refractory chronic heart failure secondary to ischemic cardiomyopathy

21 January 2018

1 reference

Autologous peripheral stem cell transplantation in patients with congestive heart failure due to ischemic heart disease

21 January 2018

1 reference

Surgical treatment for congestive heart failure with autologous adult stem cell transplantation: a prospective randomized study

21 January 2018

1 reference

Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure

21 January 2018

1 reference

21 January 2018

Human cardiac stem cells

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Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure

21 January 2018

1 reference

Pilot study to evaluate the safety and feasibility of intracoronary CD133(+) and CD133(-) CD34(+) cell therapy in patients with nonviable anterior myocardial infarction.

21 January 2018

1 reference

Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction

21 January 2018

1 reference

Cell-based myocardial repair: how should we proceed?

21 January 2018

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Safety and feasibility of autologous myoblast transplantation in patients with ischemic cardiomyopathy: four-year follow-up

21 January 2018

1 reference

Autologous skeletal myoblast transplantation in patients with nonacute myocardial infarction: 1-year follow-up.

21 January 2018

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Skeletal myoblast transplantation in ischemic heart failure: long-term follow-up of the first phase I cohort of patients.

21 January 2018

1 reference

Transcatheter transplantation of autologous skeletal myoblasts in postinfarction patients with severe left ventricular dysfunction

21 January 2018

1 reference

Percutaneous trans-coronary-venous transplantation of autologous skeletal myoblasts in the treatment of post-infarction myocardial contractility impairment: the POZNAN trial.

21 January 2018

1 reference

Autologous skeletal myoblast transplantation for the treatment of postinfarction myocardial injury: phase I clinical study with 12 months of follow-up.

21 January 2018

1 reference

Catheter-based intramyocardial injection of autologous skeletal myoblasts as a primary treatment of ischemic heart failure: clinical experience with six-month follow-up

21 January 2018

1 reference

Angiogenic growth factors and/or cellular therapy for myocardial regeneration: a comparative study

21 January 2018

1 reference

One-year follow-up of feasibility and safety of the first U.S., randomized, controlled study using 3-dimensional guided catheter-based delivery of autologous skeletal myoblasts for ischemic cardiomyopathy (CAuSMIC study).

21 January 2018

1 reference

Antiarrhythmic engineering of skeletal myoblasts for cardiac transplantation

21 January 2018

1 reference

The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: first randomized placebo-controlled study of myoblast transplantation.

21 January 2018

1 reference

Bone marrow cells regenerate infarcted myocardium

21 January 2018

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Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium

21 January 2018

1 reference

Cell-based therapy of myocardial infarction

21 January 2018

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Paracrine mechanisms in adult stem cell signaling and therapy

21 January 2018

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Clinical applications of stem cells for the heart

21 January 2018

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21 January 2018

Cardiac regeneration.

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Adult cardiac stem cells are multipotent and support myocardial regeneration

21 January 2018

1 reference

Evidence that human cardiac myocytes divide after myocardial infarction

21 January 2018

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Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion.

21 January 2018

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Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens.

21 January 2018

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Evolution of the c-kit-positive cell response to pathological challenge in the myocardium

21 January 2018

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Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages

21 January 2018

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Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes

21 January 2018

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The post-natal heart contains a myocardial stem cell population.

21 January 2018

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Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart.

21 January 2018

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Stem cells in the heart: what's the buzz all about?--Part 1: preclinical considerations

21 January 2018

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Stem cells in the heart: what's the buzz all about? Part 2: Arrhythmic risks and clinical studies.

21 January 2018

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Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction

21 January 2018

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Imaging survival and function of transplanted cardiac resident stem cells

21 January 2018

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Cardiomyocytes can be generated from marrow stromal cells in vitro

21 January 2018

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Advances in cell-based therapy for structural heart disease

21 January 2018

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Mechanisms of action of mesenchymal stem cells in cardiac repair: potential influences on the cardiac stem cell niche.

21 January 2018

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Early improvement in cardiac tissue perfusion due to mesenchymal stem cells.

21 January 2018

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Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep

21 January 2018

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Differentiation of pluripotent embryonic stem cells into cardiomyocytes.

21 January 2018

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Differentiation in vivo of cardiac committed human embryonic stem cells in postmyocardial infarcted rats.

21 January 2018

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Guided stem cell cardiopoiesis: discovery and translation

21 January 2018

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Cardiopoietic programming of embryonic stem cells for tumor-free heart repair

21 January 2018

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Morphological and molecular characterization of novel population of CXCR4+ SSEA-4+ Oct-4+ very small embryonic-like cells purified from human cord blood: preliminary report.

21 January 2018

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A population of very small embryonic-like (VSEL) CXCR4(+)SSEA-1(+)Oct-4+ stem cells identified in adult bone marrow

21 January 2018

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Morphological characterization of very small embryonic-like stem cells (VSELs) by ImageStream system analysis

21 January 2018

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Bone marrow-derived pluripotent very small embryonic-like stem cells (VSELs) are mobilized after acute myocardial infarction

21 January 2018

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Transplantation of bone marrow-derived very small embryonic-like stem cells attenuates left ventricular dysfunction and remodeling after myocardial infarction

21 January 2018

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Pilot study of rapid infusion of 2 L of 4 degrees C normal saline for induction of mild hypothermia in hospitalized, comatose survivors of out-of-hospital cardiac arrest

21 January 2018

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Therapeutic potential of human umbilical cord derived stem cells in a rat myocardial infarction model.

21 January 2018

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

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Reprogramming of human somatic cells to pluripotency with defined factors

21 January 2018

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

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Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

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Generation of functional murine cardiac myocytes from induced pluripotent stem cells

21 January 2018

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Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells

21 January 2018

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Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells.

21 January 2018

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Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages

21 January 2018

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Functional cardiomyocytes derived from human induced pluripotent stem cells

21 January 2018

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iPS programmed without c-MYC yield proficient cardiogenesis for functional heart chimerism

21 January 2018

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A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates.

21 January 2018

1 reference

Lack of regeneration of myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans with large anterior myocardial infarctions

21 January 2018

1 reference

Outcomes and risks of granulocyte colony-stimulating factor in patients with coronary artery disease.

21 January 2018

1 reference

Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions

21 January 2018

1 reference

Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial

21 January 2018

1 reference

Human amniotic fluid-derived stem cells are rejected after transplantation in the myocardium of normal, ischemic, immuno-suppressed or immuno-deficient rat

21 January 2018

1 reference

Comparison of intracoronary and transendocardial delivery of allogeneic mesenchymal cells in a canine model of acute myocardial infarction

21 January 2018

1 reference

Skeletal myoblast transplantation through a catheter-based coronary sinus approach: an effective means of improving function of infarcted myocardium

21 January 2018

1 reference

Comparison of the effects of fetal cardiomyocyte and skeletal myoblast transplantation on postinfarction left ventricular function

21 January 2018

1 reference

Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/ERC.10.99

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23 August 2017

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PubMed ID

20670189