In planta production of plant-derived and non-plant-derived adjuvants (Q37776716)

23 August 2017

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title

In planta production of plant-derived and non-plant-derived adjuvants (English)

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23 August 2017

Antonio Granell

1

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PubMed ID

20673009

23 August 2017

Asun Fernández del-Carmen

series ordinal

2

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PubMed ID

20673009

23 August 2017

Diego Orzáez

series ordinal

3

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23 August 2017

1 August 2010

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Expert Review of Vaccines

23 August 2017

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23 August 2017

9

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23 August 2017

8

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23 August 2017

843-858

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Mechanism of action of licensed vaccine adjuvants

23 August 2017

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Current status of immunological adjuvants

21 January 2018

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RLJ-NE-299A: a new plant based vaccine adjuvant.

21 January 2018

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Towards the rational design of Th1 adjuvants

21 January 2018

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Expression of the rabies virus glycoprotein in transgenic tomatoes

21 January 2018

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Plant-produced vaccines: promise and reality

21 January 2018

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Dendritic cells and immune responses to orally administered antigens

21 January 2018

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Plant cell factories and mucosal vaccines

21 January 2018

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Edible plant vaccines: applications for prophylactic and therapeutic molecular medicine.

21 January 2018

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Tomato is a highly effective vehicle for expression and oral immunization with Norwalk virus capsid protein

21 January 2018

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Interaction of cholera toxin and membrane GM1 ganglioside of small intestine

21 January 2018

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Expression of cholera toxin B subunit oligomers in transgenic potato plants.

21 January 2018

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Expression and assembly of cholera toxin B subunit (CTB) in transgenic carrot (Daucus carota L.).

21 January 2018

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Expression of the native cholera toxin B subunit gene and assembly as functional oligomers in transgenic tobacco chloroplasts

21 January 2018

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Rice-based mucosal vaccine as a global strategy for cold-chain- and needle-free vaccination

21 January 2018

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High-yield expression of a viral peptide animal vaccine in transgenic tobacco chloroplasts.

21 January 2018

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Pea-derived vaccines demonstrate high immunogenicity and protection in rabbits against rabbit haemorrhagic disease virus

21 January 2018

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Efficient induction of oral tolerance by fusing cholera toxin B subunit with allergen-specific T-cell epitopes accumulated in rice seed

21 January 2018

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Induction of oral tolerance to prevent diabetes with transgenic plants requires glutamic acid decarboxylase (GAD) and IL-4.

21 January 2018

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Expression of the B subunit of Escherichia coli heat-labile enterotoxin as a fusion protein in transgenic tomato.

21 January 2018

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Production of a fusion protein consisting of the enterotoxigenic Escherichia coli heat-labile toxin B subunit and a tuberculosis antigen in Arabidopsis thaliana.

21 January 2018

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Expression of a synthetic neutralizing epitope of porcine epidemic diarrhea virus fused with synthetic B subunit of Escherichia coli heat labile enterotoxin in rice endosperm

21 January 2018

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Mucosal immunity in mice induced by orally administered transgenic rice

21 January 2018

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Expression of an Escherichia coli antigenic fusion protein comprising the heat labile toxin B subunit and the heat stable toxin, and its assembly as a functional oligomer in transplastomic tobacco plants

21 January 2018

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Virus-like particles: passport to immune recognition

21 January 2018

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Use of viral vectors for vaccine production in plants

21 January 2018

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Cucumber mosaic virus as carrier of a hepatitis C virus-derived epitope.

21 January 2018

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Immunogenicity of papaya mosaic virus-like particles fused to a hepatitis C virus epitope: evidence for the critical function of multimerization.

21 January 2018

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Novel plant virus-based vaccine induces protective cytotoxic T-lymphocyte-mediated antiviral immunity through dendritic cell maturation

21 January 2018

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Norwalk virus-like particles as vaccines

21 January 2018

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The vaccine adjuvant extra domain A from fibronectin retains its proinflammatory properties when expressed in tobacco chloroplasts

21 January 2018

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Plant lectins: occurrence, biochemistry, functions and applications.

21 January 2018

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The tomato lectin consists of two homologous chitin-binding modules separated by an extensin-like linker

21 January 2018

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A database analysis of jacalin-like lectins: sequence-structure-function relationships

21 January 2018

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Effects of phytohemagglutinin (PHA) on the structure of midgut epithelial cells and localization of its binding sites in western tarnished plant bug, Lygus hesperus Knight.

21 January 2018

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Subcellular effects and localization of binding sites of phytohemagglutinin in the potato leafhopper, Empoasca fabae (Insecta: Homoptera: Cicadellidae).

21 January 2018

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Ribotoxin recognition of ribosomal RNA and a proposal for the mechanism of translocation

21 January 2018

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Effects of wheat germ agglutinin on human gastrointestinal epithelium: insights from an experimental model of immune/epithelial cell interaction.

21 January 2018

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A non-toxic lectin for antigen delivery of plant-based mucosal vaccines

21 January 2018

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Mucosal immunization with a ricin toxin B subunit-rotavirus NSP4 fusion protein stimulates a Th1 lymphocyte response

21 January 2018

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Synthesis of a ricin toxin B subunit-rotavirus VP7 fusion protein in potato

21 January 2018

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Expression of a ricin toxin B subunit: insulin fusion protein in edible plant tissues

21 January 2018

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M-cell targeted biodegradable PLGA nanoparticles for oral immunization against hepatitis B.

21 January 2018

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Lectin anchored stabilized biodegradable nanoparticles for oral immunization 1. Development and in vitro evaluation

21 January 2018

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M-cell targeting of whole killed bacteria induces protective immunity against gastrointestinal pathogens.

21 January 2018

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Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides for prevention of human immunodeficiency virus infection

21 January 2018

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A lectin isolated from bananas is a potent inhibitor of HIV replication

21 January 2018

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Plant lectins: potential antineoplastic drugs from bench to clinic

21 January 2018

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Biological activities and distribution of plant saponins.

21 January 2018

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Application of Quillaja saponaria extracts as oral adjuvants for plant-made vaccines

21 January 2018

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Phase 1 trial of immunological adjuvant QS-21 with a GM2 ganglioside-keyhole limpet haemocyanin conjugate vaccine in patients with malignant melanoma

21 January 2018

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Induction of homologous virus neutralizing antibodies in guinea-pigs immunized with two human immunodeficiency virus type 1 glycoprotein gp120-iscom preparations. A comparison with other adjuvant systems

21 January 2018

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QS-21 promotes an adjuvant effect allowing for reduced antigen dose during HIV-1 envelope subunit immmunization in humans

21 January 2018

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Preclinical evaluation of a synthetic Plasmodium falciparum MAP malaria vaccine in Aotus monkeys and mice.

21 January 2018

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Three double-blind, randomized trials evaluating the safety and tolerance of different formulations of the saponin adjuvant QS-21.

21 January 2018

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Effective immunotherapy against canine visceral leishmaniasis with the FML-vaccine.

21 January 2018

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Emergency vaccination of sheep against foot-and-mouth disease: protection against disease and reduction in contact transmission

21 January 2018

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21 January 2018

ISCOMs and ISCOMATRIX.

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Advances in saponin-based adjuvants

21 January 2018

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Potentiation by a novel alkaloid glycoside adjuvant of a protective cytotoxic T cell immune response specific for a preerythrocytic malaria vaccine candidate antigen

21 January 2018

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Immunobiology of the Tomatine adjuvant

21 January 2018

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Novel human polysaccharide adjuvants with dual Th1 and Th2 potentiating activity

21 January 2018

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Vaccine adjuvants: current state and future trends

21 January 2018

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Transgenic potato (Solanum tuberosum) tubers synthesize the full spectrum of inulin molecules naturally occurring in globe artichoke (Cynara scolymus) roots

21 January 2018

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Inulin-derived adjuvants efficiently promote both Th1 and Th2 immune responses

21 January 2018

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Pulmonary delivery of an inulin-stabilized influenza subunit vaccine prepared by spray-freeze drying induces systemic, mucosal humoral as well as cell-mediated immune responses in BALB/c mice.

21 January 2018

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Polysaccharide-protein complex from Lycium barbarum L. is a novel stimulus of dendritic cell immunogenicity.

21 January 2018

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Identification of a novel vaccine adjuvant that stimulates and maintains diphtheria toxoid immunity.

21 January 2018

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Stimulation of tetanus toxoid-specific immune responses by a traditional Chinese herbal medicine.

21 January 2018

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Binding of the insecticidal lectin Concanavalin A in pea aphid, Acyrthosiphon pisum (Harris) and induced effects on the structure of midgut epithelial cells.

21 January 2018

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A specific beta-glucosidase-aggregating factor is responsible for the beta-glucosidase null phenotype in maize

21 January 2018

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Maize beta-glucosidase-aggregating factor is a polyspecific jacalin-related chimeric lectin, and its lectin domain is responsible for beta-glucosidase aggregation.

21 January 2018

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Antagonistic jacalin-related lectins regulate the size of ER body-type beta-glucosidase complexes in Arabidopsis thaliana

21 January 2018

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Avenacosidase from oat: purification, sequence analysis and biochemical characterization of a new member of the BGA family of beta-glucosidases

21 January 2018

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Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1

21 January 2018

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Lectindb: a plant lectin database.

21 January 2018

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Making an ally from an enemy: plant virology and the new agriculture

21 January 2018

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Systemic Agrobacterium tumefaciens-mediated transfection of viral replicons for efficient transient expression in plants

21 January 2018

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In planta engineering of viral RNA replicons: efficient assembly by recombination of DNA modules delivered by Agrobacterium

21 January 2018

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Magnifection--a new platform for expressing recombinant vaccines in plants

21 January 2018

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Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors.

21 January 2018

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Immunoabsorbent nanoparticles based on a tobamovirus displaying protein A.

21 January 2018

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Extremely high-level and rapid transient protein production in plants without the use of viral replication

21 January 2018

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Individualized human scFv vaccines produced in plants: humoral anti-idiotype responses in vaccinated mice confirm relevance to the tumor Ig.

21 January 2018

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Heat-stable oral alga-based vaccine protects mice from Staphylococcus aureus infection.

21 January 2018

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Biochemical and immunological characterization of the plant-derived candidate human immunodeficiency virus type 1 mucosal vaccine CTB-MPR.

21 January 2018

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A mucosally targeted subunit vaccine candidate eliciting HIV-1 transcytosis-blocking Abs.

21 January 2018

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Receptor-mediated oral delivery of a bioencapsulated green fluorescent protein expressed in transgenic chloroplasts into the mouse circulatory system

21 January 2018

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Oral immunogenicity and protective efficacy in mice of transgenic rice plants producing a vaccine candidate antigen (As16) of Ascaris suum fused with cholera toxin B subunit

21 January 2018

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Expression of cholera toxin B-proinsulin fusion protein in lettuce and tobacco chloroplasts--oral administration protects against development of insulitis in non-obese diabetic mice

21 January 2018

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A plant-based cholera toxin B subunit-insulin fusion protein protects against the development of autoimmune diabetes

21 January 2018

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Plant-synthesized E. coli CFA/I fimbrial protein protects Caco-2 cells from bacterial attachment

21 January 2018

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A plant-based multicomponent vaccine protects mice from enteric diseases

21 January 2018

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Development of a plant-derived subunit vaccine candidate against hepatitis C virus

21 January 2018

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Oral immunogenicity of a plant-made, subunit, tuberculosis vaccine.

21 January 2018

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Expression of the B subunit of the heat-labile enterotoxin of Escherichia coli in tobacco mosaic virus-infected Nicotiana benthamiana plants and its characterization as mucosal immunogen and adjuvant

21 January 2018

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Expression of synthetic neutralizing epitope of porcine epidemic diarrhea virus fused with synthetic B subunit of Escherichia coli heat-labile enterotoxin in tobacco plants

21 January 2018

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Viral and murine interleukin-10 are correctly processed and retain their biological activity when produced in tobacco

21 January 2018

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Expression of a single-chain human interleukin-12 gene in transgenic tobacco plants and functional studies.

21 January 2018

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Expression of functional interleukin-12 from mouse in transgenic tomato plants.

21 January 2018

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Efficient plant-based production of chicken interleukin-12 yields a strong immunostimulatory cytokine

21 January 2018

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A novel platform for biologically active recombinant human interleukin-13 production

21 January 2018

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Recombinant mouse granulocyte-macrophage colony-stimulating factor is glycosylated in transgenic tobacco and maintains its biological activity.

21 January 2018

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Intranasal immunization with influenza virus and Korean mistletoe lectin C (KML-C) induces heterosubtypic immunity in mice

21 January 2018

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Immunological implications of the use of plant lectins for drug and vaccine targeting to the gastrointestinal tract.

21 January 2018

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Mistletoe lectins enhance immune responses to intranasally co-administered herpes simplex virus glycoprotein D2.

21 January 2018

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Enhanced mucosal and systemic immune response with intranasal immunization of mice with HIV peptides entrapped in PLG microparticles in combination with Ulex Europaeus-I lectin as M cell target.

21 January 2018

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Immunoadjuvant activity of crude lectin extracted from Momordica charantia seed

21 January 2018

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An inactivated Vero cell-grown Japanese encephalitis vaccine formulated with Advax, a novel inulin-based adjuvant, induces protective neutralizing antibody against homologous and heterologous flaviviruses

21 January 2018

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Starch microparticles as an adjuvant in immunisation: effect of route of administration on the immune response in mice

21 January 2018

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Oral vaccination against diphtheria using polyacryl starch microparticles as adjuvant

21 January 2018

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Novel polysaccharide adjuvant from the roots of Actinidia eriantha with dual Th1 and Th2 potentiating activity.

21 January 2018

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Freeing vaccine adjuvants from dangerous immunological dogma

21 January 2018

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Therapeutic effectiveness of orally administered transgenic low-alkaloid tobacco expressing human interleukin-10 in a mouse model of colitis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/ERV.10.80

1 reference

23 August 2017

1 reference

PubMed ID

20673009