Small-molecule modulators of zymogen activation in the fibrinolytic and coagulation systems (Q37780797)

23 August 2017

title

Small-molecule modulators of zymogen activation in the fibrinolytic and coagulation systems (English)

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23 August 2017

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Keiji Hasumi

1

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23 August 2017

Shingo Yamamichi

series ordinal

2

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23 August 2017

Tomotaka Harada

series ordinal

3

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23 August 2017

language of work or name

English

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publication date

16 August 2010

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23 August 2017

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23 August 2017

volume

277

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23 August 2017

issue

18

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23 August 2017

page(s)

3675-3687

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Cofactor proteins in the assembly and expression of blood clotting enzyme complexes

23 August 2017

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Serine protease mechanism and specificity

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Plasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and kringle 5 of the substrate.

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Identification of a new exosite involved in catalytic turnover by the streptokinase-plasmin activator complex during human plasminogen activation

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Novel fluorescent prothrombin analogs as probes of staphylocoagulase-prothrombin interactions

21 January 2018

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Von Willebrand factor-binding protein is a hysteretic conformational activator of prothrombin

21 January 2018

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Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice.

21 January 2018

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Molecular cloning and characterization of a full-length cDNA clone for human plasminogen

21 January 2018

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The PAN module: the N-terminal domains of plasminogen and hepatocyte growth factor are homologous with the apple domains of the prekallikrein family and with a novel domain found in numerous nematode proteins

21 January 2018

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Evidence that the conformation of unliganded human plasminogen is maintained via an intramolecular interaction between the lysine-binding site of kringle 5 and the N-terminal peptide

21 January 2018

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Lysine-50 is a likely site for anchoring the plasminogen N-terminal peptide to lysine-binding kringles

21 January 2018

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The effect of ϵ-amino caproic acid on the gross conformation of plasminogen and plasmin

21 January 2018

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Endothelial cell-mediated conversion of Glu-plasminogen to Lys-plasminogen. Further evidence for assembly of the fibrinolytic system on the endothelial cell surface

21 January 2018

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Proteomics-based discovery of a novel, structurally unique, and developmentally regulated plasminogen receptor, Plg-RKT, a major regulator of cell surface plasminogen activation

21 January 2018

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S100A10 regulates plasminogen-dependent macrophage invasion

21 January 2018

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Conformational studies of human plasminogen and plasminogen fragments: evidence for a novel third conformation of plasminogen

21 January 2018

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Structure and ligand binding determinants of the recombinant kringle 5 domain of human plasminogen

21 January 2018

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Solution structure and functional characterization of human plasminogen kringle 5

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The AH-site of plasminogen and two C-terminal fragments. A weak lysine-binding site preferring ligands not carrying a free carboxylate function

21 January 2018

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The reciprocal effects of epsilon-aminohexanoic acid and chloride ion on the activation of human [Glu1]plasminogen by human urokinase

21 January 2018

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Skizzle is a novel plasminogen- and plasmin-binding protein from Streptococcus agalactiae that targets proteins of human fibrinolysis to promote plasmin generation

21 January 2018

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Serum amyloid A enhances plasminogen activation: implication for a role in colon cancer

21 January 2018

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The Mechanism of Plasminogen Activation and the Variability of the Fibrin Effector during Tissue‐type Plasminogen Activator—mediated Fibrinolysis

21 January 2018

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Inhibitory effects of lysine analogues on t-PA induced whole blood clot lysis

21 January 2018

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The mysteries of lipoprotein(a)

21 January 2018

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Apolipoprotein(a) kringle IV repeat number predicts risk for coronary heart disease.

21 January 2018

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cDNA sequence of human apolipoprotein(a) is homologous to plasminogen

21 January 2018

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Molecular definition of the extreme size polymorphism in apolipoprotein(a).

21 January 2018

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Lipoprotein(a) modulation of endothelial cell surface fibrinolysis and its potential role in atherosclerosis

21 January 2018

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Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen: a novel mechanism for lipoprotein(a)-mediated inhibition of plasminogen activation

21 January 2018

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Nonlysine-analog plasminogen modulators promote autoproteolytic generation of plasmin(ogen) fragments with angiostatin-like activity

21 January 2018

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Stachybotrydial selectively enhances fibrin binding and activation of Glu-plasminogen

21 January 2018

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Structure-function relationships in the interaction between the urokinase-type plasminogen activator and its receptor

21 January 2018

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The urokinase receptor: focused cell surface proteolysis, cell adhesion and signaling

21 January 2018

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Urokinase and urokinase receptor: a paracrine/autocrine system regulating cell migration and invasiveness

21 January 2018

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Structure, function and antagonists of urokinase-type plasminogen activator

21 January 2018

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Activation of pro-urokinase and plasminogen on human sarcoma cells: a proteolytic system with surface-bound reactants

21 January 2018

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Activation of single-chain urokinase-type plasminogen activator by platelet-associated plasminogen: a mechanism for stimulation of fibrinolysis by platelets.

21 January 2018

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PARticipation in inflammation

21 January 2018

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Characterization of the complementary deoxyribonucleic acid and gene coding for human prothrombin

21 January 2018

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Restricted active site docking by enzyme-bound substrate enforces the ordered cleavage of prothrombin by prothrombinase

21 January 2018

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Regulated cleavage of prothrombin by prothrombinase: repositioning a cleavage site reveals the unique kinetic behavior of the action of prothrombinase on its compound substrate

21 January 2018

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Membrane-dependent interaction of factor Xa and prothrombin with factor Va in the prothrombinase complex

21 January 2018

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Dual modulation of prothrombin activation by the cyclopentapeptide plactin

21 January 2018

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Exosites in the substrate specificity of blood coagulation reactions

21 January 2018

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The hyaluronic acid-binding protease: a novel vascular and inflammatory mediator?

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

The G534E polymorphism of the gene encoding the factor VII-activating protease is associated with cardiovascular risk due to increased neointima formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

The Marburg I variant (G534E) of the factor VII-activating protease determines liver fibrosis in hepatitis C infection by reduced proteolysis of platelet-derived growth factor BB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

Altered factor VII activating protease expression in murine hepatic fibrosis and its influence on hepatic stellate cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

Purification and characterization of a novel hyaluronan-binding protein (PHBP) from human plasma: it has three EGF, a kringle and a serine protease domain, similar to hepatocyte growth factor activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

Activation of proPHBSP, the zymogen of a plasma hyaluronan binding serine protease, by an intermolecular autocatalytic mechanism

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

Regulation mechanism of the serine protease activity of plasma hyaluronan binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

Extracellular RNA is a natural cofactor for the (auto-)activation of Factor VII-activating protease (FSAP)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

Factor VII and single-chain plasminogen activator-activating protease: activation and autoactivation of the proenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

Hepatic injury-specific conversion of mouse plasma hyaluronan binding protein to the active hetero-dimer form

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

Polyamine-promoted autoactivation of plasma hyaluronan-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

Polyamines and nucleic acids during development of the chick embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

Purpurin as a Specific Inhibitor of Spermidine-Induced Autoactivation of the Protease Plasma Hyaluronan-Binding Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

21 January 2018

The Protein C Pathway

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07783.X

SMTP-4D, -5D, -6D, -7D and -8D, a New Series of the Non-lysine-analog Plasminogen Modulators with a D-Amino Acid Moiety

21 January 2018

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COCI

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.56.832

Antibiotic A10255 (thioplabin) enhances fibrin binding and activation of plasminogen

12 April 2024

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COCI

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.55.83

Isolation of SMTP-3, 4, 5 and -6, novel analogs of staplabin, and their effects on plasminogen activation and fibrinolysis

12 April 2024

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.51.1059

SMTP-1 and -2, novel analogs of staplabin produced by Stachybotrys microspora IFO30018

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.50.172

Identifiers

DOI

10.1111/J.1742-4658.2010.07783.X

1 reference

23 August 2017

1 reference