Orthosteric- and allosteric-induced ligand-directed trafficking at GPCRs (Q37784750)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20812150%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Orthosteric- and allosteric-induced ligand-directed trafficking at GPCRs (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20812150%20AND%20SRC:MED&resulttype=core&format=json

G protein-coupled receptor

13 February 2020

main subject

0 references

3

Craig W Lindsley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20812150%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2

P Jeffrey Conn

1 reference

23 August 2017

1

Gregory J Digby

1 reference

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13 February 2020

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20812150

5 July 2024

publication date

1 September 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20812150%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

13 February 2020

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20812150/?tool=EBI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20812150

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20812150/pdf/?tool=EBI

5 July 2024

file format

Portable Document Format

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https://europepmc.org/articles/PMC3821179

5 July 2024

1 reference

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https://europepmc.org/articles/PMC3821179?pdf=render

5 July 2024

file format

Portable Document Format

online access status

open access

content deliverer

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Current Opinion in Drug Discovery and Development

5 July 2024

published in

1 reference

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13 February 2020

volume

13

1 reference

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13 February 2020

issue

5

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13 February 2020

page(s)

587-594

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Identification of orthosteric and allosteric site mutations in M2 muscarinic acetylcholine receptors that contribute to ligand-selective signaling bias

13 February 2020

cites work

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Differential regulation of muscarinic M1 receptors by orthosteric and allosteric ligands

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6 September 2017

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6 September 2017

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Biochemical and pharmacological control of the multiplicity of coupling at G-protein-coupled receptors

6 September 2017

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6 September 2017

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G protein-coupled receptor allosterism and complexing

6 September 2017

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Drug efficacy at G protein-coupled receptors

6 September 2017

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6 September 2017

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Rat cerebral cortex corticotropin-releasing hormone receptors: evidence for receptor coupling to multiple G-proteins

6 September 2017

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G(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtype

6 September 2017

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The M3 muscarinic acetylcholine receptor expressed in HEK-293 cells signals to phospholipase D via G12 but not Gq-type G proteins: regulators of G proteins as tools to dissect pertussis toxin-resistant G proteins in receptor-effector coupling

6 September 2017

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Morphine-activated opioid receptors elude desensitization by beta-arrestin

6 September 2017

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The relationship between agonist intrinsic activity and the rate of endocytosis of muscarinic receptors in a human neuroblastoma cell line

6 September 2017

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Muscarinic m1 receptor-stimulated adenylate cyclase activity in Chinese hamster ovary cells is mediated by Gs alpha and is not a consequence of phosphoinositidase C activation

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Contrasting effects of allosteric and orthosteric agonists on m1 muscarinic acetylcholine receptor internalization and down-regulation

6 September 2017

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14 September 2017

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Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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23 June 2018

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23 June 2018

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23 June 2018

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23 June 2018

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23 June 2018

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On the analysis of pharmacological experiments in terms of an allosteric receptor model

23 June 2018

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Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2.

23 June 2018

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1 September 2018

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Functional coupling with Galpha(q) and Galpha(i1) protein subunits promotes high-affinity agonist binding to the neurotensin receptor NTS-1 expressed in Escherichia coli

1 September 2018

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1 September 2018

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Allosteric receptors after 30 years

1 September 2018

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12 December 2020

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12 December 2020

On the definition of efficacy

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12 December 2020

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12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20812150%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference