Mechanisms by which thiazolidinediones induce anti-cancer effects in cancers in digestive organs. (Q37786227)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20824291%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Mechanisms by which thiazolidinediones induce anti-cancer effects in cancers in digestive organs (English)

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13 February 2020

1

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13 February 2020

author name string

Toshikatsu Okumura

series ordinal

1

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23 August 2017

language of work or name

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8 September 2010

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20824291%20AND%20SRC:MED&resulttype=core&format=json

Journal of Gastroenterology

13 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20824291%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

45

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20824291%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

11

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13 February 2020

page(s)

1097-1102

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PPARgamma : a nuclear regulator of metabolism, differentiation, and cell growth

13 February 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00535-010-0310-9

Troglitazone induces G1 arrest by p27(Kip1) induction that is mediated by inhibition of proteasome in human gastric cancer cells.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00535-010-0310-9

Thiazolidinediones: a new class of antidiabetic drugs

21 January 2018

1 reference

12 December 2020

Activation of PPARgamma inhibits cell growth and induces apoptosis in human gastric cancer cells

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12 December 2020

Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolytic processing

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12 December 2020

Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest.

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12 December 2020

Molecular requirements for epithelial-mesenchymal transition during tumor progression

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12 December 2020

Thiazolidinediones and the risk of lung, prostate, and colon cancer in patients with diabetes.

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12 December 2020

Matrix metalloproteinases and tumor metastasis

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12 December 2020

Plasminogen activator inhibitor-I and tumour growth, invasion, and metastasis.

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12 December 2020

Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes

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12 December 2020

Rosiglitazone sensitizes MDA-MB-231 breast cancer cells to anti-tumour effects of tumour necrosis factor-alpha, CH11 and CYC202.

1 reference

12 December 2020

Peroxisome proliferator activated receptor-gamma ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells

1 reference

12 December 2020

Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer.

1 reference

12 December 2020

Troglitazone increases expression of E-cadherin and claudin 4 in human pancreatic cancer cells

1 reference

12 December 2020

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

12 December 2020

Peroxisome proliferator-activated receptor gamma regulates E-cadherin expression and inhibits growth and invasion of prostate cancer

1 reference

12 December 2020

Apoptosis induced by troglitazone is both peroxisome proliferator-activated receptor-gamma- and ERK-dependent in human non-small lung cancer cells.

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12 December 2020

Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1.

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12 December 2020

Activation of peroxisome proliferator-activated receptor gamma by troglitazone inhibits cell growth through the increase of p27KiP1 in human. Pancreatic carcinoma cells

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12 December 2020

PPAR gamma ligand-induced apoptosis through a p53-dependent mechanism in human gastric cancer cells

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12 December 2020

Peroxisome proliferator-activated receptor gamma ligands induce cell cycle arrest and apoptosis in human renal carcinoma cell lines

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12 December 2020

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

1 reference

12 December 2020

PPARgamma-independent antitumor effects of thiazolidinediones

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12 December 2020

Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells

1 reference

12 December 2020

Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines

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12 December 2020

Effect of peroxisome proliferator activated receptor gamma ligands on growth and gene expression profiles of gastric cancer cells.

1 reference

12 December 2020

Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists

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12 December 2020

Review: Peroxisome proliferator-activated receptor gamma and adipose tissue--understanding obesity-related changes in regulation of lipid and glucose metabolism

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12 December 2020

Troglitazone sensitizes tumor cells to TRAIL-induced apoptosis via down-regulation of FLIP and Survivin.

1 reference

12 December 2020

Peroxisome proliferator-activated receptor-gamma agonists suppress adrenocortical tumor cell proliferation and induce differentiation

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12 December 2020

Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARgamma independent mechanisms

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12 December 2020

Troglitazone, a peroxisome proliferator-activated receptor gamma ligand, induces growth inhibition and apoptosis of HepG2 human liver cancer cells

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12 December 2020

Troglitazone and liver injury: in search of answers

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12 December 2020

Prognostic impact of survivin, cyclin D1, integrin beta1, and VEGF in patients with small adenocarcinoma of stage I lung cancer

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12 December 2020

Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists

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12 December 2020

Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonists

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12 December 2020

Troglitazone has a scavenging effect on reactive oxygen species

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12 December 2020

Growth arrest by troglitazone is mediated by p27Kip1 accumulation, which results from dual inhibition of proteasome activity and Skp2 expression in human hepatocellular carcinoma cells.

1 reference

12 December 2020

Claudin proteins in human cancer: promising new targets for diagnosis and therapy

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12 December 2020

Troglitazone inhibits cyclin D1 expression and cell cycling independently of PPARgamma in normal mouse skin keratinocytes.

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12 December 2020

A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation

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12 December 2020

Activation of peroxisome proliferator-activated receptor-gamma decreases pancreatic cancer cell invasion through modulation of the plasminogen activator system

1 reference

12 December 2020

IAPs: what's in a name?

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12 December 2020

Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis

1 reference

12 December 2020

Cell cycle, CDKs and cancer: a changing paradigm

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12 December 2020

Rosiglitazone suppresses human lung carcinoma cell growth through PPARgamma-dependent and PPARgamma-independent signal pathways

1 reference

12 December 2020

Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARgamma

1 reference

12 December 2020

Peroxisome proliferator-activated receptor gamma-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells.

1 reference

12 December 2020

Involvement of MEK-ERK signaling pathway in the inhibition of cell growth by troglitazone in human pancreatic cancer cells.

1 reference

12 December 2020

Troglitazone inhibits growth of MCF-7 breast carcinoma cells by targeting G1 cell cycle regulators

1 reference

12 December 2020

Peroxisome proliferator-activated receptor gamma and cancers

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12 December 2020

Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor gamma in non-small cell lung cancer

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12 December 2020

10.1007/S00535-010-0310-9

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20824291%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

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