New β-lactam antibiotics and β-lactamase inhibitors (Q37788685)

23 August 2017

New β-lactam antibiotics and β-lactamase inhibitors (English)

1 reference

23 August 2017

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Karen Bush

1

1 reference

PubMed ID

20839927

23 August 2017

Mark J Macielag

series ordinal

2

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PubMed ID

20839927

23 August 2017

language of work or name

English

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publication date

1 October 2010

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Expert Opinion on Therapeutic Patents

23 August 2017

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23 August 2017

20

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23 August 2017

1277-1293

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23 August 2017

10

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Updated functional classification of beta-lactamases

23 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

21 January 2018

Emerging cephalosporins

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

BRL 17421, a novel beta-lactam antibiotic, highly resistant to beta-lactamases, giving high and prolonged serum levels in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

TOC-39, a novel parenteral broad-spectrum cephalosporin with excellent activity against methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Anti-MRSA beta-lactams in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

A randomized, double-blind trial comparing ceftobiprole medocaril with vancomycin plus ceftazidime for the treatment of patients with complicated skin and skin-structure infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Phase 2 study of ceftaroline versus standard therapy in treatment of complicated skin and skin structure infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Synthesis and SAR of novel parenteral anti-pseudomonal cephalosporins: discovery of FR264205.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Activity of cephalosporin CXA-101 (FR264205) against Pseudomonas aeruginosa and Burkholderia cepacia group strains and isolates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Cir and Fiu proteins in the outer membrane of Escherichia coli catalyze transport of monomeric catechols: study with beta-lactam antibiotics containing catechol and analogous groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Iron-regulated outer membrane proteins of Escherichia coli K-12 and mechanism of action of catechol-substituted cephalosporins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

In vitro activity of CP-65,207, a new penem antimicrobial agent, in comparison with those of other agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Reduction of in-source collision-induced dissociation and thermolysis of sulopenem prodrugs for quantitative liquid chromatography/electrospray ionization mass spectrometric analysis by promoting sodium adduct formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

In vitro activity of tebipenem, a new oral carbapenem antibiotic, against penicillin-nonsusceptible Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

4-Substituted trinems as broad spectrum beta-lactamase inhibitors: structure-based design, synthesis, and biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

In vitro activity of LK-157, a novel tricyclic carbapenem as broad-spectrum {beta}-lactamase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Interaction of azthreonam and related monobactams with beta-lactamases from gram-negative bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Kinetic interactions of tazobactam with beta-lactamases from all major structural classes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Efficacy of piperacillin combined with the Penem beta-lactamase inhibitor BLI-489 in murine models of systemic infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Establishment of in vitro susceptibility testing methodologies and comparative activities of piperacillin in combination with the penem {beta}-lactamase inhibitor BLI-489.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

NXL104 combinations versus Enterobacteriaceae with CTX-M extended-spectrum beta-lactamases and carbapenemases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Thermodynamic evaluation of a covalently bonded transition state analogue inhibitor: inhibition of beta-lactamases by phosphonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Crystal structure of Enterobacter cloacae 908R class C beta-lactamase bound to iodo-acetamido-phenyl boronic acid, a transition-state analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

The deacylation mechanism of AmpC beta-lactamase at ultrahigh resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-beta-lactamase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Antibiotic resistance in bacteria: novel metalloenzyme inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Inhibition of metallo-beta-lactamases by pyridine monothiocarboxylic acid analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

Detection of the new metallo-beta-lactamase VIM-19 along with KPC-2, CMY-2 and CTX-M-15 in Klebsiella pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2010.515588

10.1517/13543776.2010.515588

21 January 2018

Identifiers

DOI

1 reference

23 August 2017

1 reference

PubMed ID

20839927