Pharmacogenetics of osteoporosis-related bone fractures: moving towards the harmonization and validation of polymorphism diagnostic tools (Q37791155)

23 August 2017

Pharmacogenetics of osteoporosis-related bone fractures: moving towards the harmonization and validation of polymorphism diagnostic tools (English)

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23 August 2017

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Karen Rojo Venegas

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23 August 2017

Margarita Aguilera Gómez

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23 August 2017

John Allan Eisman

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23 August 2017

Antonio García Sánchez

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23 August 2017

María J Faus Dader

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23 August 2017

Miguel A Calleja Hernández

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23 August 2017

1 September 2010

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23 August 2017

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23 August 2017

11

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23 August 2017

9

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23 August 2017

1287-1303

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Osteoporosis prevention, diagnosis, and therapy

23 August 2017

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Diagnosis of osteoporosis and assessment of fracture risk

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Relationship between changes in bone mineral density and fracture risk reduction with antiresorptive drugs: some issues with meta-analyses

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Choice of study phenotype in osteoporosis genetic research

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Genome-wide association study of circulating vitamin D levels

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Genetics of osteoporosis: accelerating pace in gene identification and validation

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Decision criteria for rational selection of homogeneous genotyping platforms for pharmacogenomics testing in clinical diagnostics.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group.

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Approaches to the targeting of treatment for osteoporosis

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Case finding for the management of osteoporosis with FRAX--assessment and intervention thresholds for the UK.

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Cost-effective osteoporosis treatment thresholds: the United States perspective

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Review of osteoporosis pharmacotherapy for geriatric patients

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Bisphosphonates: mechanism of action and role in clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

17beta-estradiol downregulates beta3-integrin expression in differentiating and mature human osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

The roles of parathyroid hormone and calcitonin in bone remodeling: prospects for novel therapeutics

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Strontium ranelate--data on vertebral and nonvertebral fracture efficacy and safety: mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Prediction of bone density from vitamin D receptor alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Searching for osteoporosis genes in the post-genome era: progress and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Osteoclasts, integrins, and osteoporosis.

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption.

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Comparison of WOMAC with SF-36 for OA of the knee or hip.

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Brittle bones--fragile molecules: disorders of collagen gene structure and expression

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Polymorphisms in the estrogen receptor beta (ESR2) gene are associated with bone mineral density in Caucasian men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

The future of genetic studies of complex human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Genetic epidemiological approaches to the search for osteoporosis genes

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Prospects of genetic epidemiology in the 21st century

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Multiple genetic loci for bone mineral density and fractures

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Pharmacogenetics of osteoporosis and the prospect of individualized prognosis and individualized therapy

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Human genetics of osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Polymorphisms in the osteoprotegerin gene are associated with osteoporotic fractures

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Serum osteoprotegerin (OPG) and the A163G polymorphism in the OPG promoter region are related to peripheral measures of bone mass and fracture odds ratios.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Association of the osteoprotegerin gene polymorphisms with bone mineral density in postmenopausal women.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

New sequence variants associated with bone mineral density

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Association of TNFSF11 gene promoter polymorphisms with bone mineral density in postmenopausal women.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

The combinations of polymorphisms in vitamin D receptor, osteoprotegerin and tumour necrosis factor superfamily member 11 genes are associated with bone mineral density

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Gene expression profiling in monocytes and SNP association suggest the importance of the STAT1 gene for osteoporosis in both Chinese and Caucasians

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

LRP5 Polymorphisms and response to risedronate treatment in osteoporotic men.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with peak bone mass in non-sedentary men: results from the Odense androgen study.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

21 January 2018

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https://api.crossref.org/works/10.2217%2FPGS.10.116

Integrin beta3 Leu33Pro polymorphism and risk of hip fracture: 25 years follow-up of 9233 adults from the general population

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Genetic variation in candidate osteoporosis genes, bone mineral density, and fracture risk: the study of osteoporotic fractures

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Vitamin D receptor gene polymorphisms are associated with the risk of fractures in postmenopausal women, independently of bone mineral density

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Contribution of the collagen I alpha1 and vitamin D receptor genes to the risk of hip fracture in elderly women.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Association between vitamin D receptor gene polymorphisms, falls, balance and muscle power: results from two independent studies (APOSS and OPUS).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Age-specific effects of estrogen receptors' polymorphisms on the bone traits in healthy fertile women: the BONTURNO study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Meta-analysis of COL1A1 Sp1 polymorphism in relation to bone mineral density and osteoporotic fracture

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

The -1997 G/T and Sp1 polymorphisms in the collagen type I alpha1 (COLIA1) gene in relation to changes in femoral neck bone mineral density and the risk of fracture in the elderly: the Rotterdam study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Genetic testing in clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Inheritance and drug response

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

2009 Santa Fe Bone symposium

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Anti-hip fracture efficacy of biophosphonates: a Bayesian analysis of clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Non-response to osteoporosis treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Adverse effects of bisphosphonates: implications for osteoporosis management

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Effectiveness of alendronate treatment in postmenopausal women with osteoporosis: relationship with BsmI vitamin D receptor genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

No major effect of estrogen receptor beta gene RsaI polymorphism on bone mineral density and response to alendronate therapy in postmenopausal osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Two polymorphisms in the vitamin D receptor gene--association with bone mass and 5-year change in bone mass with or without hormone-replacement therapy in postmenopausal women: the Danish Osteoporosis Prevention Study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

New Insights Into the Molecular Mechanisms of Action of Bisphosphonates

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Postural instability of extremely obese individuals improves after a body weight reduction program entailing specific balance training.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Genetic techniques for pharmacogenetic analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Vitamin D receptor polymorphisms in differentiated thyroid carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Vitamin D receptor genotypes influence the success of calcitriol therapy for recurrent vertebral fracture in osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Large-scale population-based study shows no evidence of association between common polymorphism of the VDR gene and BMD in British women

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Estrogen receptor polymorphisms and the risk of endometrial cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Reduced bone density and osteoporosis associated with a polymorphic Sp1 binding site in the collagen type I alpha 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Association and linkage analysis of COL1A1 and AHSG gene polymorphisms with femoral neck bone geometric parameters in both Caucasian and Chinese nuclear families.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Genetic variation in the RANKL/RANK/OPG signaling pathway is associated with bone turnover and bone mineral density in men

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Common Genetic Variation of the Low-Density Lipoprotein Receptor-Related Protein 5 and 6 Genes Determines Fracture Risk in Elderly White Men

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Vitamin D receptor gene BsmI and TaqI polymorphisms and fracture risk: A meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Vitamin D Receptor Genotype and the Risk of Bone Fractures in Women

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Treatment of patients with postmenopausal osteoporosis is worthwhile. The position of the International Osteoporosis Foundation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

Differential Genetic Effects of ESR1 Gene Polymorphisms on Osteoporosis Outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.10.116

21 January 2018

Identifiers

DOI

10.2217/PGS.10.116

1 reference

23 August 2017

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