An introduction to the molecular basics of aryl hydrocarbon receptor biology (Q37792070)

23 August 2017

title

An introduction to the molecular basics of aryl hydrocarbon receptor biology (English)

1 reference

intracellular signaling peptides and proteins

23 August 2017

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20868221

19 July 2024

signal transduction

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20868221

regulation of gene expression

19 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20868221

19 July 2024

author name string

Josef Abel

1

1 reference

23 August 2017

Thomas Haarmann-Stemmann

2

1 reference

23 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20868221

19 July 2024

publication date

1 November 2010

1 reference

full work available at URL

23 August 2017

http://www.degruyter.com/view/j/bchm.2010.391.issue-11/bc.2010.128/bc.2010.128.xml

1 reference

https://www.degruyter.com/document/doi/10.1515/bc.2010.128/pdf

19 July 2024

1 reference

19 July 2024

1 reference

23 August 2017

volume

391

1 reference

23 August 2017

issue

11

1 reference

23 August 2017

page(s)

1235-1248

1 reference

Indirubin and indigo are potent aryl hydrocarbon receptor ligands present in human urine

23 August 2017

cites work

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Regulation of the Cyp2a5 gene involves an aryl hydrocarbon receptor-dependent pathway

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Intrinsic function of the aryl hydrocarbon (dioxin) receptor as a key factor in female reproduction

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Novel dithiolethione-modified nonsteroidal anti-inflammatory drugs in human hepatoma HepG2 and colon LS180 cells.

21 January 2018

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Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex

21 January 2018

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Binding of aryl hydrocarbon receptor (AhR) to AhR-interacting protein - The role of hsp90

21 January 2018

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Tissue distribution and function of the Aryl hydrocarbon receptor repressor (AhRR) in C57BL/6 and Aryl hydrocarbon receptor deficient mice

21 January 2018

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Ah receptor: dioxin-mediated toxic responses as hints to deregulated physiologic functions

21 January 2018

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Luteolin enhances the bioavailability of benzo(a)pyrene in human colon carcinoma cells

21 January 2018

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Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor

21 January 2018

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Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways. Demonstration of competition and compensation

21 January 2018

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Protein kinase C modulates regulation of the CYP1A1 gene by the aryl hydrocarbon receptor

21 January 2018

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Identification of aryl hydrocarbon receptor as a putative Wnt/beta-catenin pathway target gene in prostate cancer cells

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.128

Effect of curcumin on the aryl hydrocarbon receptor and cytochrome P450 1A1 in MCF-7 human breast carcinoma cells

21 January 2018

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Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2010.128

Sulindac regulates the aryl hydrocarbon receptor-mediated expression of Phase 1 metabolic enzymes in vivo and in vitro

21 January 2018

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A family of unusually spliced biologically active transcripts encoded by a Drosophila clock gene

21 January 2018

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The basic helix-loop-helix/PAS factor Sim is associated with hsp90. Implications for regulation by interaction with partner factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Aryl hydrocarbon receptor imported into the nucleus following ligand binding is rapidly degraded via the cytosplasmic proteasome following nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Induction of cytochrome P450 1A1 gene expression, oxidative stress, and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Association of the dioxin receptor with the Mr 90,000 heat shock protein: a structural kinship with the glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Ligand binding and activation of the Ah receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Transforming growth factor-beta1 coregulates mRNA expression of aryl hydrocarbon receptor and cell-cycle-regulating genes in human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Control of distal antennal identity and tarsal development in Drosophila by spineless-aristapedia, a homolog of the mammalian dioxin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Molecular cloning of the human AH receptor gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Identification of c-Src as the integral component of the cytosolic Ah receptor complex, transducing the signal of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) through the protein phosphorylation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The immune phenotype of AhR null mouse mutants: not a simple mirror of xenobiotic receptor over-activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

PPARalpha activation potentiates AhR-induced CYP1A1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Regulation of mouse Ah receptor (Ahr) gene basal expression by members of the Sp family of transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Identification of functional domains of the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Analysis of the murine AhR gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Effects of histone deacetylase inhibitors on the Ah receptor gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Dietary polyphenols increase paraoxonase 1 gene expression by an aryl hydrocarbon receptor-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The PAS superfamily: sensors of environmental and developmental signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Analysis of the transcriptional regulation and molecular function of the aryl hydrocarbon receptor repressor in human cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (AhR) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Regulation of dioxin receptor function by different beta-carboline alkaloids

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Aryl hydrocarbon receptors: diversity and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Role of coactivators in transcriptional activation by the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Agonist and chemopreventative ligands induce differential transcriptional cofactor recruitment by aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Zinc finger transcription factor Slug is a novel target gene of aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Nuclear localization and export signals of the human aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Cell density regulates intracellular localization of aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Phosphorylation of nuclear localization signal inhibits the ligand-dependent nuclear import of aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Human NAD(P)H:quinone oxidoreductase (NQO1) gene structure and induction by dioxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Cross-talk between 2,3,7,8-tetrachlorodibenzo-p-dioxin and testosterone signal transduction pathways in LNCaP prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The active form of human aryl hydrocarbon receptor (AHR) repressor lacks exon 8, and its Pro 185 and Ala 185 variants repress both AHR and hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Ultraviolet-B exposure of human skin induces cytochromes P450 1A1 and 1B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (Aryl hydrocarbon) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The immunophilin-like protein XAP2 regulates ubiquitination and subcellular localization of the dioxin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Recent advances in understanding the mechanisms of TCDD immunotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

AHR-mediated immunomodulation: the role of altered gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Coordinate regulation of Phase I and II xenobiotic metabolisms by the Ah receptor and Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-mediated membrane translocation of c-Src protein kinase in liver WB-F344 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The aryl hydrocarbon receptor is required for developmental closure of the ductus venosus in the neonatal mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Chromosomal localization of the human AHR locus encoding the structural gene for the Ah receptor to 7p21-->p15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Effects of aryl hydrocarbon receptor null mutation and in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on prostate and seminal vesicle development in C57BL/6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The developmentally-regulated Smoc2 gene is repressed by Aryl-hydrocarbon receptor (Ahr) signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Protein kinase C modulates aryl hydrocarbon receptor nuclear translocator protein-mediated transactivation potential in a dimer context

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Cytochrome P450 1A1 gene regulation by UVB involves crosstalk between the aryl hydrocarbon receptor and nuclear factor kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Aryl hydrocarbon receptor degradation-promoting factor (ADPF) and the control of the xenobiotic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway: role of the transcription activaton and DNA binding of AhR

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

A cycloheximide-sensitive factor regulates TCDD-induced degradation of the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The significance of the nongenomic pathway in mediating inflammatory signaling of the dioxin-activated Ah receptor to cause toxic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Molecular pathways in dermatotoxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Identification of a novel mechanism of regulation of Ah (dioxin) receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Timing is everything: consequences of transient and sustained AhR activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Aryl hydrocarbon receptor-inducible or constitutive expression of human UDP glucuronosyltransferase UGT1A6

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The role of cytochrome P450 in tumour development and progression and its potential in therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The Drosophila single-minded gene encodes a helix-loop-helix protein that acts as a master regulator of CNS midline development

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Antagonistic and agonistic effects of indigoids on the transformation of an aryl hydrocarbon receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Expression of human and mouse genes encoding polkappa: testis-specific developmental regulation and AhR-dependent inducible transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Dioxin receptor is a ligand-dependent E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Molecular mechanism of transcriptional repression of AhR repressor involving ANKRA2, HDAC4, and HDAC5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Epigallocatechin gallate inhibits aryl hydrocarbon receptor gene transcription through an indirect mechanism involving binding to a 90 kDa heat shock protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The aryl hydrocarbon receptor directly regulates expression of the potent mitogen epiregulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Reduction of UV-induced skin tumors in hairless mice by selective COX-2 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The transcriptional signature of dioxin in human hepatoma HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The Caenorhabditis elegans aryl hydrocarbon receptor, AHR-1, regulates neuronal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Identification of a novel dioxin-inducible cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Inhibitory aryl hydrocarbon receptor-estrogen receptor alpha cross-talk and mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Lipoxin A4: a new class of ligand for the Ah receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Activation of the Ah receptor signaling pathway by prostaglandins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Hypersensitivity of aryl hydrocarbon receptor-deficient mice to lipopolysaccharide-induced septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

A ligand for the aryl hydrocarbon receptor isolated from lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The aryl hydrocarbon receptor: a perspective on potential roles in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Aryl hydrocarbon receptor null mice develop cardiac hypertrophy and increased hypoxia-inducible factor-1alpha in the absence of cardiac hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-kappaB component RelB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Human CYP1B1 is regulated by estradiol via estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

PPARalpha transcriptionally induces AhR expression in Caco-2, but represses AhR pro-inflammatory effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Activation of the aryl hydrocarbon receptor by berberine in HepG2 and H4IIE cells: Biphasic effect on CYP1A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Functional involvement of the Brahma/SWI2-related gene 1 protein in cytochrome P4501A1 transcription mediated by the aryl hydrocarbon receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Structure and expression of the mouse AhR nuclear translocator (mArnt) gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Transcriptional activation of cathepsin D gene expression by 17beta-estradiol: mechanism of aryl hydrocarbon receptor-mediated inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Rapid and transient induction of CYP1A1 gene expression in human cells by the tryptophan photoproduct 6-formylindolo[3,2-b]carbazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Characteristic expression of aryl hydrocarbon receptor repressor gene in human tissues: organ-specific distribution and variable induction patterns in mononuclear cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

The aryl hydrocarbon receptor constitutively represses c-myc transcription in human mammary tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Involvement of the xenobiotic response element (XRE) in Ah receptor-mediated induction of human UDP-glucuronosyltransferase 1A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Suppression of experimental autoimmune uveoretinitis by inducing differentiation of regulatory T cells via activation of aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.128

Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo.

21 January 2018

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Identifiers

DOI

10.1515/BC.2010.128

1 reference

23 August 2017

1 reference