Genetic shifts of Neisseria meningitidis serogroup B antigens and the quest for a broadly cross-protective vaccine (Q37798011)

23 August 2017

Genetic shifts of Neisseria meningitidis serogroup B antigens and the quest for a broadly cross-protective vaccine (English)

1 reference

23 August 2017

Neisseria meningitidis

1 reference

0 references

2

Ray Borrow

1 reference

23 August 2017

Xilian Bai

1

1 reference

23 August 2017

1 October 2010

1 reference

Expert Review of Vaccines

23 August 2017

1 reference

23 August 2017

9

1 reference

23 August 2017

10

1 reference

23 August 2017

1203-1217

1 reference

Conquering the meningococcus

23 August 2017

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Epidemic meningitis, meningococcaemia, and Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Immunologic response of man to group B meningococcal polysaccharide vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Protective efficacy of a serogroup B meningococcal vaccine in Sao Paulo, Brazil

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

A prospective study of the effectiveness of the New Zealand meningococcal B vaccine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Use of an observational cohort study to estimate the effectiveness of the New Zealand group B meningococcal vaccine in children aged under 5 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Persisting immune responses indicating long-term protection after booster dose with meningococcal group B outer membrane vesicle vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Functional and specific antibody responses in adult volunteers in new zealand who were given one of two different meningococcal serogroup B outer membrane vesicle vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

A universal vaccine for serogroup B meningococcus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Vaccine potential of the Neisseria meningitidis 2086 lipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Multi-locus sequence typing: a tool for global epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Genetics and evolution of Neisseria meningitidis: importance for the epidemiology of meningococcal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Role of selection in the emergence of lineages and the evolution of virulence in Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Characterization of fHbp, nhba (gna2132), nadA, porA, sequence type (ST), and genomic presence of IS1301 in group B meningococcal ST269 clonal complex isolates from England and Wales

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Molecular typing of meningococci: recommendations for target choice and nomenclature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Meningococcal carriage and disease--population biology and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Use of variable-number tandem repeats to examine genetic diversity of Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Complete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

New functional identity for the DNA uptake sequence in transformation and its presence in transcriptional terminators

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

The impact of homologous recombination on the generation of diversity in bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

The relative contributions of recombination and mutation to the divergence of clones of Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Prospects for vaccine prevention of meningococcal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Capsule switching of Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Genome sequencing reveals widespread virulence gene exchange among human Neisseria species

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Asymmetrical distribution of Neisseria miniature insertion sequence DNA repeats among pathogenic and nonpathogenic Neisseria strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Genome analysis and strain comparison of correia repeats and correia repeat-enclosed elements in pathogenic Neisseria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Modulation of the mtrCDE-encoded efflux pump gene complex of Neisseria meningitidis due to a Correia element insertion sequence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Genome flexibility in Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Sequence diversity within the argF, fbp and recA genes of natural isolates of Neisseria meningitidis: interspecies recombination within the argF gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Adaptive evolution of highly mutable loci in pathogenic bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

A novel phase variation mechanism in the meningococcus driven by a ligand-responsive repressor and differential spacing of distal promoter elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Multiple mechanisms of phase variation of PorA in Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Variable expression of the Opc outer membrane protein in Neisseria meningitidis is caused by size variation of a promoter containing poly-cytidine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Microsatellite instability regulates transcription factor binding and gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Expression of the meningococcal adhesin NadA is controlled by a transcriptional regulator of the MarR family

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Phase variable type III restriction-modification systems of host-adapted bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

The phasevarion: phase variation of type III DNA methyltransferases controls coordinated switching in multiple genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Intercontinental spread of a genetically distinctive complex of clones of Neisseria meningitidis causing epidemic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Mechanisms of neisserial serum resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Complement. First of two parts

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Secretor status, smoking and carriage of Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Parental smoking, socioeconomic factors, and risk of invasive meningococcal disease in children: a population based case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

CD46 in meningococcal disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Human immunity to the meningococcus. II. Development of natural immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Imaging of disease dynamics during meningococcal sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

The role of neisserial Opa proteins in interactions with host cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Intimate adhesion of Neisseria meningitidis to human epithelial cells is under the control of the crgA gene, a novel LysR-type transcriptional regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Pilus-mediated adhesion of Neisseria meningitidis: the essential role of cell contact-dependent transcriptional upregulation of the PilC1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Neisseria meningitidis producing the Opc adhesin binds epithelial cell proteoglycan receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Immunoproteomic analysis of the development of natural immunity in subjects colonized by Neisseria meningitidis reveals potential vaccine candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Quest for a broad-range vaccine against Neisseria meningitidis serogroup B: implications of genetic variations of the surface-exposed proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Recombinant Neisseria meningitidis transferrin binding protein A protects against experimental meningococcal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Outer membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as 'virulence genes'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Point mutation in meningococcal por A gene associated with increased endemic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Immunogenicity and reactogenicity in UK infants of a novel meningococcal vesicle vaccine containing multiple class 1 (PorA) outer membrane proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Identification of variable region differences in Neisseria meningitidis class 3 protein sequences among five group B serotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Sequence variation in the porB gene from B:P1.4 meningococci causing New Zealand's epidemic

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Immunization with recombinant Opc outer membrane protein from Neisseria meningitidis: influence of sequence variation and levels of expression on the bactericidal immune response against meningococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

The meningococcal transferrin-binding proteins 1 and 2 are both surface exposed and generate bactericidal antibodies capable of killing homologous and heterologous strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Sequence conservation of pilus subunits in Neisseria meningitidis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Lipooligosaccharides (LOS) of Neisseria gonorrhoeae and Neisseria meningitidis have components that are immunochemically similar to precursors of human blood group antigens. Carbohydrate sequence specificity of the mouse monoclonal antibodies that r

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Affinity-purified human immunoglobulin G that binds a lacto-N-neotetraose-dependent lipooligosaccharide structure is bactericidal for serogroup B Neisseria meningitidis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Genetically modified L3,7 and L2 lipooligosaccharides from Neisseria meningitidis serogroup B confer a broad cross-bactericidal response

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Distribution of surface protein variants among hyperinvasive meningococci: implications for vaccine design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Meningococcal protein antigens and vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Exploring the evolution of diversity in pathogen populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Vaccination against meningococcal disease in Europe: review and recommendations for the use of conjugate vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Additive and synergistic bactericidal activity of antibodies directed against minor outer membrane proteins of Neisseria meningitidis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Neisseria lactamica protects against experimental meningococcal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Outer membrane vesicles of Neisseria lactamica as a potential mucosal adjuvant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Phase I safety and immunogenicity study of a candidate meningococcal disease vaccine based on Neisseria lactamica outer membrane vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Neisseria meningitidis: an overview of the carriage state

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Carriage of serogroup C meningococci 1 year after meningococcal C conjugate polysaccharide vaccination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

NadA, a novel vaccine candidate of Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

NadA diversity and carriage in Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Distribution and genetic variability of three vaccine components in a panel of strains representative of the diversity of serogroup B meningococcus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Prevalence of factor H-binding protein variants and NadA among meningococcal group B isolates from the United States: implications for the development of a multicomponent group B vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Measuring antigen-specific bactericidal responses to a multicomponent vaccine against serogroup B meningococcus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Characterization of fHbp, nhba (gna2132), nadA, porA, and sequence type in group B meningococcal case isolates collected in England and Wales during January 2008 and potential coverage of an investigational group B meningococcal vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Antibody to genome-derived neisserial antigen 2132, a Neisseria meningitidis candidate vaccine, confers protection against bacteremia in the absence of complement-mediated bactericidal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Vaccine-induced opsonophagocytic immunity to Neisseria meningitidis group B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Vaccination against Neisseria meningitidis using three variants of the lipoprotein GNA1870

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Structural Basis for the Immunogenic Properties of the Meningococcal Vaccine Candidate LP2086

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Rapid genetic grouping of factor h-binding protein (genome-derived neisserial antigen 1870), a promising group B meningococcal vaccine candidate

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Sequence diversity of the factor H binding protein vaccine candidate in epidemiologically relevant strains of serogroup B Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

The modular architecture of meningococcal factor H-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Frequency of factor H-binding protein modular groups and susceptibility to cross-reactive bactericidal activity in invasive meningococcal isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Impaired immunogenicity of a meningococcal factor H-binding protein vaccine engineered to eliminate factor h binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

The meningococcal vaccine candidate neisserial surface protein A (NspA) binds to factor H and enhances meningococcal resistance to complement

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Using DNA microarrays to study host-microbe interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Microarray analysis of bacterial pathogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Transcriptome-based antigen identification for Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

The analysis of Neisseria meningitidis proteomes: Reference maps and their applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Inventory of the proteins in Neisseria meningitidis serogroup B strain MC58.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Outer membrane vesicles of the VA-MENGOC-BC vaccine against serogroup B of Neisseria meningitidis: Analysis of protein components by two-dimensional gel electrophoresis and mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Cross-linking analysis of antigenic outer membrane protein complexes of Neisseria meningitidis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Post-genomic vaccine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Solution structure of the immunodominant domain of protective antigen GNA1870 of Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Solution Structure of the Factor H-binding Protein, a Survival Factor and Protective Antigen of Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Microbial genomes and vaccine design: refinements to the classical reverse vaccinology approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Gene expression profile in Neisseria meningitidis and Neisseria lactamica upon host-cell contact: from basic research to vaccine development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Functional genomics of Neisseria meningitidis pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Comparative genomics identifies the genetic islands that distinguish Neisseria meningitidis, the agent of cerebrospinal meningitis, from other Neisseria species

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

The influence of genomics and proteomics on the development of potential vaccines against meningococcal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Antigenic Shift and Increased Incidence of Meningococcal Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Phase 1 first-in-human studies of the reactogenicity and immunogenicity of a recombinant meningococcal NspA vaccine in healthy adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

Repeat-associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.116

21 January 2018

Identifiers

DOI

10.1586/ERV.10.116

1 reference

23 August 2017

1 reference

PubMed ID

20923270