Protein metabolism in human obesity: a shift in focus from whole-body to skeletal muscle (Q37821747)

23 August 2017

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title

Protein metabolism in human obesity: a shift in focus from whole-body to skeletal muscle (English)

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23 August 2017

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2

Lawrence J Mandarino

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23 August 2017

Christos S Katsanos

1

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23 August 2017

16 December 2010

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23 August 2017

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23 August 2017

19

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23 August 2017

3

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23 August 2017

469-475

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Inspiratory muscle activity during incremental exercise in obese men.

23 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

The association between adiposity and the response to resistance training among pre- and early-pubertal boys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

The muscle strength and size response to upper arm, unilateral resistance training among adults who are overweight and obese

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Muscle strength is a marker of insulin resistance in patients with type 2 diabetes: a pilot study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Regulation of skeletal muscle mitochondrial fatty acid metabolism in lean and obese individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Changes in basal and insulin and amino acid response of whole body and skeletal muscle proteins in obese men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Splanchnic glucose and amino acid metabolism in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Differential effects of insulin resistance on leucine and glucose kinetics in obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Plasma Amino Acid Levels and Insulin Secretion in Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

The greater contribution of gluconeogenesis to glucose production in obesity is related to increased whole-body protein catabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Regional muscle and adipose tissue amino acid metabolism in lean and obese women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Insulin-induced decline of plasma amino acid concentrations in obese subjects with and without non-insulin-dependent diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Increased protein turnover in obese women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Differential effect of insulin on whole-body proteolysis and glucose metabolism in normal-weight, obese, and reduced-obese women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Age and aerobic exercise training effects on whole body and muscle protein metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Exercise training and protein metabolism: influences of contraction, protein intake, and sex-based differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Effects of adiposity and 30 days of caloric restriction upon protein metabolism in moderately vs. severely obese women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

The influence of sex on the protein anabolic response to insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Muscle protein synthesis and balance responsiveness to essential amino acids ingestion in the presence of elevated plasma free fatty acid concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Differential insulin sensitivities of glucose, amino acid, and albumin metabolism in elderly men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Insulin sensitivity of protein and glucose metabolism in human forearm skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Insulin action on protein metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Influence of amino acid administration on whole-body leucine kinetics and resting metabolic rate in postabsorptive normal subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Effect of insulin and plasma amino acid concentrations on leucine metabolism in man. Role of substrate availability on estimates of whole body protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Physical frailty and body composition in obese elderly men and women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

21 January 2018

Beyond body mass index

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Effects of ageing and human whole body and muscle protein turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Truncal fat in relation to total body fat: influences of age, sex, ethnicity and fatness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Catabolism of aging: is it an inflammatory process?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Tissue and whole-body protein synthesis in immature Zucker rats and their relationship to protein deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Morphological and biochemical alterations of skeletal muscles from the genetically obese (ob/ob) mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Antioxidant alpha-lipoic acid and protein turnover in insulin-resistant rat muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Diet-induced obesity alters protein synthesis: tissue-specific effects in fasted versus fed mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Reduced amino acid availability inhibits muscle protein synthesis and decreases activity of initiation factor eIF2B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Amino acids are necessary for the insulin-induced activation of mTOR/S6K1 signaling and protein synthesis in healthy and insulin resistant human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Facts, noise and wishful thinking: muscle protein turnover in aging and human disuse atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Lean and obese Zucker rats exhibit different patterns of p70s6 kinase regulation in the tibialis anterior muscle in response to high-force muscle contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Effect of insulin on human skeletal muscle protein synthesis is modulated by insulin-induced changes in muscle blood flow and amino acid availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Acute energy deprivation affects skeletal muscle protein synthesis and associated intracellular signaling proteins in physically active adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Ceramide content is increased in skeletal muscle from obese insulin-resistant humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Mechanical stimuli of skeletal muscle: implications on mTOR/p70s6k and protein synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Cellular mechanisms regulating protein synthesis and skeletal muscle hypertrophy in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Impaired overload-induced hypertrophy in obese Zucker rat slow-twitch skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Insulin action on muscle protein kinetics and amino acid transport during recovery after resistance exercise.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Insulin-induced vasodilatation and endothelial function in obesity/insulin resistance. Effects of troglitazone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Obesity blunts insulin-mediated microvascular recruitment in human forearm muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Effects of Intrabrachial metacholine infusion on muscle capillary recruitment and forearm glucose uptake during physiological hyperinsulinemia in obese, insulin-resistant individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Insulin stimulates human skeletal muscle protein synthesis via an indirect mechanism involving endothelial-dependent vasodilation and mammalian target of rapamycin complex 1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Effect of insulin on system A amino acid transport in human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Role of mitochondrial dysfunction in insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Muscle Protein Synthesis Measured by Stable Isotope Techniques in Man: The Effects of Feeding and Fasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Resistance exercise and nutrition to counteract muscle wasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Resistance exercise: good for more than just Grandma and Grandpa's muscles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

In vivo measurement of synthesis rate of individual skeletal muscle mitochondrial proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Heterogeneity of pig intestinal D-glucose transport systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Study of differences in peripheral muscle strength of lean versus obese women: an allometric approach

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Differences in quadriceps muscle strength and fatigue between lean and obese subjects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Insulin resistance: a contributing factor to age-related muscle mass loss?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Sex Differences in the Effect of Obesity on Human Plasma Tryptophan/Large Neutral Amino Acid Ratio

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Insulin-dependent metabolism of branched-chain amino acids in obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Protein Metabolism in Human Obesity: Relationship with Glucose and Lipid Metabolism and with Visceral Adipose Tissue

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Effect of poor diabetic control and obesity on whole body protein metabolism in man

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Protein metabolism in obesity: effects of body fat distribution and hyperinsulinemia on leucine turnover

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Physical activity patterns in normal, overweight and obese individuals using minute-by-minute accelerometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Receptor externalization determines sustained contractile responses to endothelin-1 in the rat aorta

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Latency, duration and dose response relationships of amino acid effects on human muscle protein synthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Regulation of muscle protein by amino acids

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Sarcopenic obesity: does muscle loss cause fat gain? Lessons from rheumatoid arthritis and osteoarthritis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Comparative amino acid and protein metabolism in obese and non-obese Zucker rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Effect of exercise and obesity on skeletal muscle amino acid uptake

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Mechanism for the increased skeletal muscle protein degradation in the obese zucker rat

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Protein turnover in insulin-treated, alloxan-diabetic lean and obese Zucker rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Impaired anabolic response of muscle protein synthesis is associated with S6K1 dysregulation in elderly humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Blood flow restriction during low-intensity resistance exercise increases S6K1 phosphorylation and muscle protein synthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Insulin resistance of muscle protein metabolism in aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Interaction between insulin sensitivity and muscle perfusion on glucose uptake in human skeletal muscle: evidence for capillary recruitment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

31P nuclear magnetic resonance analysis of frog skin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

The underappreciated role of muscle in health and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

Effects of energy restriction and exercise on skeletal muscle and adipose tissue in women as measured by magnetic resonance imaging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

inferred from DOI database lookup

7 January 2021

based on heuristic

Muscle protein turnover in the perfused hindquarters of lean and genetically obese-diabetic (db/db) mice

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

inferred from DOI database lookup

7 January 2021

based on heuristic

Resistance training preserves fat-free mass without impacting changes in protein metabolism after weight loss in older women

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2010.290

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/OBY.2010.290

1 reference

23 August 2017

1 reference

PubMed ID

21164506