TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs (Q37822821)

23 August 2017

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title

TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs (English)

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23 August 2017

1

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Sacha Jensen

series ordinal

2

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author name string

Penny Handford

series ordinal

3

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23 August 2017

language of work or name

English

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publication date

1 January 2011

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23 August 2017

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23 August 2017

volume

433

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23 August 2017

issue

2

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23 August 2017

page(s)

263-276

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Biogenesis and function of fibrillin assemblies

23 August 2017

cites work

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Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta

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Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein

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Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites

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Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability

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Making sense of latent TGFbeta activation

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Latent TGF-beta binding proteins: extracellular matrix association and roles in TGF-beta activation

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Mutations in fibrillin-1 cause congenital scleroderma: stiff skin syndrome

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In frame fibrillin-1 gene deletion in autosomal dominant Weill-Marchesani syndrome

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The molecular genetics of Marfan syndrome and related microfibrillopathies

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Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices

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Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils

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Fibrillins 1 and 2 perform partially overlapping functions during aortic development

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Differential expression of fibrillin-3 adds to microfibril variety in human and avian, but not rodent, connective tissues

21 January 2018

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A variant in the fibrillin-3 gene is associated with TGF-β and inhibin B levels in women with polycystic ovary syndrome

21 January 2018

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Fibrillins in adult human ovary and polycystic ovary syndrome: is fibrillin-3 affected in PCOS?

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Null mutations in LTBP2 cause primary congenital glaucoma

21 January 2018

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LTBP2 null mutations in an autosomal recessive ocular syndrome with megalocornea, spherophakia, and secondary glaucoma

21 January 2018

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Oligodontia is caused by mutation in LTBP3, the gene encoding latent TGF-beta binding protein 3.

21 January 2018

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Mutations in LTBP4 cause a syndrome of impaired pulmonary, gastrointestinal, genitourinary, musculoskeletal, and dermal development

21 January 2018

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Sequence and expression of a novel member (LTBP-4) of the family of latent transforming growth factor-beta binding proteins

21 January 2018

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Identification and characterization of a new latent transforming growth factor-beta-binding protein, LTBP-4

21 January 2018

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Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome

21 January 2018

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A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2

21 January 2018

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Comparison of clinical presentations and outcomes between patients with TGFBR2 and FBN1 mutations in Marfan syndrome and related disorders.

21 January 2018

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Disruption of the latent transforming growth factor-beta binding protein-1 gene causes alteration in facial structure and influences TGF-beta bioavailability

21 January 2018

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Developmental expression of latent transforming growth factor beta binding protein 2 and its requirement early in mouse development

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Bone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailability

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Bone defects in latent TGF-beta binding protein (Ltbp)-3 null mice; a role for Ltbp in TGF-beta presentation

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Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung

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Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer

21 January 2018

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ENU mutagenesis reveals a novel phenotype of reduced limb strength in mice lacking fibrillin 2.

21 January 2018

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Structure of the integrin binding fragment from fibrillin-1 gives new insights into microfibril organization

21 January 2018

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Solution structure of the transforming growth factor beta-binding protein-like module, a domain associated with matrix fibrils

21 January 2018

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Solution Structure of the Third TB Domain from LTBP1 Provides Insight into Assembly of the Large Latent Complex that Sequesters Latent TGF-β

21 January 2018

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Solution structure and dynamics of a calcium binding epidermal growth factor-like domain pair from the neonatal region of human fibrillin-1

21 January 2018

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Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders

21 January 2018

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alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity

21 January 2018

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Cell adhesion and integrin binding to recombinant human fibrillin-1

21 January 2018

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Structure and interdomain interactions of a hybrid domain: a disulphide-rich module of the fibrillin/LTBP superfamily of matrix proteins

21 January 2018

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21 January 2018

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An extracellular matrix protein of jellyfish homologous to mammalian fibrillins forms different fibrils depending on the life stage of the animal

21 January 2018

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Immunohistochemical localization of elastin, fibrillins and microfibril-associated glycoprotein-1 in the developing periodontal ligament of the rat molar

21 January 2018

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Microfibrillar elements of the dermal matrix

21 January 2018

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Fibrillin assembly requires fibronectin.

21 January 2018

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Fibrillin-1 microfibril deposition is dependent on fibronectin assembly

21 January 2018

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Functional evolution of the microfibril-associated glycoproteins

21 January 2018

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Deficiency in microfibril-associated glycoprotein-1 leads to complex phenotypes in multiple organ systems

21 January 2018

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In vivo studies of mutant fibrillin-1 microfibrils

21 January 2018

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Homotypic fibrillin-1 interactions in microfibril assembly

21 January 2018

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Biogenesis of extracellular microfibrils: Multimerization of the fibrillin-1 C terminus into bead-like structures enables self-assembly

21 January 2018

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Thioredoxins and glutaredoxins as facilitators of protein folding.

21 January 2018

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Targeting of bone morphogenetic protein growth factor complexes to fibrillin

21 January 2018

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The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix

21 January 2018

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MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils

21 January 2018

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Protein interaction studies of MAGP-1 with tropoelastin and fibrillin-1

21 January 2018

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Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.

21 January 2018

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LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101320

The microfibrillar proteins MAGP-1 and fibrillin-1 form a ternary complex with the chondroitin sulfate proteoglycan decorin

21 January 2018

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Latent TGF-beta-binding protein 2 binds to DANCE/fibulin-5 and regulates elastic fiber assembly

21 January 2018

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Identification of FBN1 gene mutations in patients with ectopia lentis and marfanoid habitus

21 January 2018

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Integrins during evolution: evolutionary trees and model organisms

21 January 2018

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Molecular analysis of fibulin-5 function during de novo synthesis of elastic fibers

21 January 2018

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Fibulin-4 regulates expression of the tropoelastin gene and consequent elastic-fibre formation by human fibroblasts

21 January 2018

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Fibulin-2 and fibulin-5 cooperatively function to form the internal elastic lamina and protect from vascular injury

21 January 2018

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Growth control by EGF repeats of the C. elegans Fibulin-1C isoform

21 January 2018

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Hemicentins: what have we learned from worms?

21 January 2018

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Latent transforming growth factor-beta binding protein domains involved in activation and transglutaminase-dependent cross-linking of latent transforming growth factor-beta

21 January 2018

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SMART 6: recent updates and new developments

21 January 2018

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

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Recent progress towards a molecular understanding of Marfan syndrome

21 January 2018

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21 January 2018

Identifiers

DOI

10.1042/BJ20101320

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23 August 2017

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