Measuring low levels of protein aggregation by sedimentation velocity (Q37824159)

23 August 2017

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title

Measuring low levels of protein aggregation by sedimentation velocity (English)

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23 August 2017

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John P Gabrielson

1

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23 August 2017

Kelly K Arthur

series ordinal

2

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23 August 2017

publication date

25 December 2010

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23 August 2017

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23 August 2017

volume

54

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23 August 2017

issue

1

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23 August 2017

page(s)

83-91

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Modern applications of analytical ultracentrifugation

23 August 2017

cites work

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Effects of protein aggregates: an immunologic perspective

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Structure-immunogenicity relationships of therapeutic proteins

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Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products

7 January 2021

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Quantitation of aggregate levels in a recombinant humanized monoclonal antibody formulation by size-exclusion chromatography, asymmetrical flow field flow fractionation, and sedimentation velocity

7 January 2021

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Is any measurement method optimal for all aggregate sizes and types?

7 January 2021

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Detection of protein aggregates by sedimentation velocity analytical ultracentrifugation (SV-AUC): sources of variability and their relative importance

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMETH.2010.12.030

A bayesian approach for quantifying trace amounts of antibody aggregates by sedimentation velocity analytical ultracentrifugation.

7 January 2021

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Common excipients impair detection of protein aggregates during sedimentation velocity analytical ultracentrifugation

7 January 2021

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Precision of protein aggregation measurements by sedimentation velocity analytical ultracentrifugation in biopharmaceutical applications

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A critical review of analytical ultracentrifugation and field flow fractionation methods for measuring protein aggregation

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Quantitation of aggregates in therapeutic proteins using sedimentation velocity analytical ultracentrifugation: practical considerations that affect precision and accuracy

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A model for sedimentation in inhomogeneous media. I. Dynamic density gradients from sedimenting co-solutes

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A model for sedimentation in inhomogeneous media. II. Compressibility of aqueous and organic solvents.

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Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

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Size-distribution analysis of proteins by analytical ultracentrifugation: strategies and application to model systems

7 January 2021

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Determination of molecular parameters by fitting sedimentation data to finite-element solutions of the Lamm equation

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Boundary analysis in sedimentation transport experiments: a procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profile

7 January 2021

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A method for directly fitting the time derivative of sedimentation velocity data and an alternative algorithm for calculating sedimentation coefficient distribution functions.

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Using prior knowledge in the determination of macromolecular size-distributions by analytical ultracentrifugation

7 January 2021

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Macromolecular size-and-shape distributions by sedimentation velocity analytical ultracentrifugation.

7 January 2021

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Calculating sedimentation coefficient distributions by direct modeling of sedimentation velocity concentration profiles

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7 January 2021

Identifiers

DOI

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23 August 2017

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