Effects of specific chemical suppressors of plasminogen activator inhibitor-1 in cardiovascular diseases (Q37824876)

23 August 2017

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title

Effects of specific chemical suppressors of plasminogen activator inhibitor-1 in cardiovascular diseases (English)

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23 August 2017

cardiovascular disease

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Jun-Ichi Suzuki

1

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23 August 2017

Masahito Ogawa

2

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23 August 2017

Susumu Muto

3

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23 August 2017

Akiko Itai

4

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23 August 2017

Yasunobu Hirata

5

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23 August 2017

Mitsuaki Isobe

6

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23 August 2017

Ryozo Nagai

7

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23 August 2017

language of work or name

English

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publication date

3 January 2011

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Expert Opinion on Investigational Drugs

23 August 2017

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23 August 2017

20

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23 August 2017

2

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23 August 2017

255-264

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A role for the plasminogen activator system in inflammation and neurodegeneration in the central nervous system during experimental allergic encephalomyelitis

23 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Plasminogen activator inhibitor (PAI)-1 in vascular inflammation and thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Plasminogen activator inhibitor-1 in vascular thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

PAI-1 and kidney fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Positive feedback loop between plasminogen activator inhibitor-1 and transforming growth factor-beta1 during renal fibrosis in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Adenovirus-mediated transfer of siRNA against PAI-1 mRNA ameliorates hepatic fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Elaboration of type-1 plasminogen activator inhibitor from adipocytes. A potential pathogenetic link between obesity and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

The role of plasminogen activator inhibitor 1 in renal and cardiovascular diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Plasminogen activator inhibitor-1 predicts coronary in-stent restenosis of drug-eluting stents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Two-way interactions between inflammation and coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Plasminogen activator inhibitor type-1 deficiency does not influence the outcome of murine pneumococcal pneumonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Promigratory effect of plasminogen activator inhibitor-1 on invasive breast cancer cell populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

The urokinase plasminogen activator system: a rich source of tumour markers for the individualised management of patients with cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Myocardial remodeling in viral heart disease: possible interactions between inflammatory mediators and MMP-TIMP system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Structure-activity relationships of new 2-acylamino-3-thiophenecarboxylic acid dimers as plasminogen activator inhibitor-1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

A novel inhibitor of plasminogen activator inhibitor-1 provides antithrombotic benefits devoid of bleeding effect in nonhuman primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Design, synthesis, and evaluation of orally active inhibitors of plasminogen activator inhibitor-1 (PAI-1) production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Synthesis and evaluation of 1,4-diphenylbutadiene derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Tiplaxtinin, a novel, orally efficacious inhibitor of plasminogen activator inhibitor-1: design, synthesis, and preclinical characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Evaluation of PAI-039 [{1-benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic acid], a novel plasminogen activator inhibitor-1 inhibitor, in a canine model of coronary artery thrombosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

On the role of plasminogen activator inhibitor-1 in adipose tissue development and insulin resistance in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Pivotal role of PAI-1 in a murine model of hepatic vein thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Characterization and comparative evaluation of a structurally unique PAI-1 inhibitor exhibiting oral in-vivo efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

S35225 is a direct inhibitor of Plasminogen Activator Inhibitor type-1 activity in the blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Efficacy and safety of tenecteplase in combination with enoxaparin, abciximab, or unfractionated heparin: the ASSENT-3 randomised trial in acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Primary versus tenecteplase-facilitated percutaneous coronary intervention in patients with ST-segment elevation acute myocardial infarction (ASSENT-4 PCI): randomised trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Primary angioplasty vs. early routine post-fibrinolysis angioplasty for acute myocardial infarction with ST-segment elevation: the GRACIA-2 non-inferiority, randomized, controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

A randomized trial comparing the effect of ramipril and losartan in survivors of ST-elevation myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Effect of atorvastatin on haemostasis, fibrinolysis and inflammation in normocholesterolaemic patients with coronary artery disease: a post hoc analysis of data from a prospective, randomized, double-blind study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Thiazolidinediones down-regulate plasminogen activator inhibitor type 1 expression in human vascular endothelial cells: A possible role for PPARgamma in endothelial function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Troglitazone reduces plasminogen activator inhibitor-1 expression and secretion in cultured human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Cardiovascular risk and thiazolidinediones--what do meta-analyses really tell us?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Thiazolidinedione drugs and cardiovascular risks: a science advisory from the American Heart Association and American College of Cardiology Foundation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Immunosuppressive therapy for active lymphocytic myocarditis: virological and immunologic profile of responders versus nonresponders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Interferon-beta treatment eliminates cardiotropic viruses and improves left ventricular function in patients with myocardial persistence of viral genomes and left ventricular dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

The contribution of the exosite residues of plasminogen activator inhibitor-1 to proteinase inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Pharmacological inhibition and genetic deficiency of plasminogen activator inhibitor-1 attenuates angiotensin II/salt-induced aortic remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Gene polymorphisms for plasminogen activator inhibitor-1/tissue plasminogen activator and development of allograft coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: a gene targeting and gene transfer study in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Single-bolus tenecteplase compared with front-loaded alteplase in acute myocardial infarction: the ASSENT-2 double-blind randomised trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

Plasminogen Activator Inhibitor 1 Expression is Regulated by the Inflammatory Mediators Interleukin-1α, Tumor Necrosis Factor-α, Transforming Growth Factor-β and Oncostatin M in Human Cardiac Myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2011.546784

10.1517/13543784.2011.546784

21 January 2018

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DOI

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release_sbwimiioindexjaybdaqpot45m

23 August 2017

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24 November 2022

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