Update on the endocannabinoid system as an anticancer target (Q37829751)

24 August 2017

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title

Update on the endocannabinoid system as an anticancer target (English)

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24 August 2017

endocannabinoid system

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author name string

Anna Maria Malfitano

1

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24 August 2017

Elena Ciaglia

2

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24 August 2017

Giuseppina Gangemi

3

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24 August 2017

Patrizia Gazzerro

4

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24 August 2017

Chiara Laezza

5

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24 August 2017

Maurizio Bifulco

6

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24 August 2017

language of work or name

English

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publication date

19 January 2011

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Expert Opinion on Therapeutic Targets

24 August 2017

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24 August 2017

15

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24 August 2017

3

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24 August 2017

297-308

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The endocannabinoid signalling system: biochemical aspects

24 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Molecular characterization of a peripheral receptor for cannabinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

International Union of Pharmacology. XXVII. Classification of cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Immunohistochemical description of the endogenous cannabinoid system in the rat cerebellum and functionally related nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabinoid CB2 receptors in human brain inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

The orphan receptor GPR55 is a novel cannabinoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

In silico patent searching reveals a new cannabinoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

The molecular logic of endocannabinoid signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

The endocannabinoid system, eating behavior and energy homeostasis: the end or a new beginning?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Targeting the endocannabinoid system in cancer therapy: a call for further research

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabinoids and cancer: pros and cons of an antitumour strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Anandamide inhibits adhesion and migration of breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Delta9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabinoid receptors as novel targets for the treatment of melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabinoids as potential new therapy for the treatment of gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Anandamide levels in human female reproductive tissues: solid-phase extraction and measurement by ultraperformance liquid chromatography tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabinoids and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Endocannabinoid metabolism in human glioblastomas and meningiomas compared to human non-tumour brain tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

2-arachidonoylglycerol: a novel inhibitor of androgen-independent prostate cancer cell invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Possible endocannabinoid control of colorectal cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Anandamide and other N-acylethanolamines in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabinoids in pancreatic cancer: correlation with survival and pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

The levels of the endocannabinoid receptor CB2 and its ligand 2-arachidonoylglycerol are elevated in endometrial carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Biochemistry of the endogenous ligands of cannabinoid receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Fatty acid amide hydrolase in prostate cancer: association with disease severity and outcome, CB1 receptor expression and regulation by IL-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Expression and function of fatty acid amide hydrolase in prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Regulation of inflammatory pain by inhibition of fatty acid amide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: growth inhibition by receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Apoptosis induced in HepG2 cells by the synthetic cannabinoid WIN: involvement of the transcription factor PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Increased expressions of cannabinoid receptor-1 and transient receptor potential vanilloid-1 in human prostate carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Role of cannabinoids in chronic liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

The CB1/CB2 receptor agonist WIN-55,212-2 reduces viability of human Kaposi's sarcoma cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Predominant CB2 receptor expression in endothelial cells of glioblastoma in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabinoid receptor activation induces apoptosis through tumor necrosis factor alpha-mediated ceramide de novo synthesis in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Delta9-tetrahydrocannabinol inhibits cell cycle progression in human breast cancer cells through Cdc2 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Increased expression of TRPV1 in squamous cell carcinoma of the human tongue

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Anandamide inhibits Cdk2 and activates Chk1 leading to cell cycle arrest in human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: involvement of CB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Synergistic antiproliferative and apoptotic effects induced by epidermal growth factor receptor and protein kinase a inhibitors in human prostatic cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Rimonabant-induced apoptosis in leukemia cell lines: activation of caspase-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabinoids and ceramide: two lipids acting hand-by-hand

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

AAV-mediated gene transfer of tissue inhibitor of metalloproteinases-1 inhibits vascular tumor growth and angiogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Inhibition of cancer cell invasion by cannabinoids via increased expression of tissue inhibitor of matrix metalloproteinases-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor-suppressor efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Endocannabinoid system modulation in cancer biology and therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and of Ras farnesylation mediate antitumor effects of anandamide in human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

R(+)-methanandamide induces cyclooxygenase-2 expression in human neuroglioma cells via a non-cannabinoid receptor-mediated mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

R(+)-methanandamide-induced cyclooxygenase-2 expression in H4 human neuroglioma cells: possible involvement of membrane lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Metabolism of anandamide by COX-2 is necessary for endocannabinoid-induced cell death in tumorigenic keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Opposing actions of endocannabinoids on cholangiocarcinoma growth: recruitment of Fas and Fas ligand to lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Pharmacology of cannabinoid CB1 and CB2 receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Emerging drugs for obesity therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Human sperm anatomy: ultrastructural localization of the cannabinoid1 receptor and a potential role of anandamide in sperm survival and acrosome reaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

A pilot clinical study of Delta9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.553606

10.1517/14728222.2011.553606

21 January 2018

Identifiers

DOI

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24 August 2017

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