Analysis of CPAF mutants: new functions, new questions (the ins and outs of a chlamydial protease). (Q37844146)

1 July 2018

title

Analysis of CPAF mutants: new functions, new questions (the ins and outs of a chlamydial protease). (English)

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1 July 2018

author name string

Patrik M Bavoil

series ordinal

1

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1 July 2018

Gerald I Byrne

series ordinal

2

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1 July 2018

publication date

1 August 2014

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1 July 2018

published in

Pathogens and disease

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1 July 2018

volume

71

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1 July 2018

issue

3

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1 July 2018

page(s)

287-291

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1 July 2018

Reassessing the role of the secreted protease CPAF in Chlamydia trachomatis infection through genetic approaches

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3 July 2018

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A path forward for the chlamydial virulence factor CPAF

3 July 2018

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3 July 2018

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3 July 2018

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CPAF: a Chlamydial protease in search of an authentic substrate

3 July 2018

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Immunolabeling artifacts and the need for live-cell imaging

3 July 2018

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Structural characterization of a novel Chlamydia pneumoniae type III secretion-associated protein, Cpn0803

3 July 2018

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Targeting of a chlamydial protease impedes intracellular bacterial growth

3 July 2018

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Chlamydia protease-like activity factor (CPAF): characterization of proteolysis activity in vitro and development of a nanomolar affinity CPAF zymogen-derived inhibitor

3 July 2018

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The Chlamydia protease CPAF regulates host and bacterial proteins to maintain pathogen vacuole integrity and promote virulence

3 July 2018

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Altered protein secretion of Chlamydia trachomatis in persistently infected human endocervical epithelial cells

3 July 2018

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Chlamydia trachomatis infection causes mitotic spindle pole defects independently from its effects on centrosome amplification

3 July 2018

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Chlamydia trachomatis secretion of an immunodominant hypothetical protein (CT795) into host cell cytoplasm.

3 July 2018

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A Chlamydia trachomatis OmcB C-terminal fragment is released into the host cell cytoplasm and is immunogenic in humans

3 July 2018

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Immunization with live and dead Chlamydia muridarum induces different levels of protective immunity in a murine genital tract model: correlation with MHC class II peptide presentation and multifunctional Th1 cells

3 July 2018

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Chlamydia trachomatis secretion of hypothetical protein CT622 into host cell cytoplasm via a secretion pathway that can be inhibited by the type III secretion system inhibitor compound 1.

3 July 2018

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Cleavage of the NF-κB family protein p65/RelA by the chlamydial protease-like activity factor (CPAF) impairs proinflammatory signaling in cells infected with Chlamydiae

3 July 2018

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Histone methylation by NUE, a novel nuclear effector of the intracellular pathogen Chlamydia trachomatis

3 July 2018

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Secretion of the chlamydial virulence factor CPAF requires the Sec-dependent pathway

3 July 2018

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Autoprocessing and self-activation of the secreted protease CPAF in Chlamydia-infected cells

3 July 2018

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Killing me softly: chlamydial use of proteolysis for evading host defenses

3 July 2018

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Identification of Chlamydia trachomatis CT621, a protein delivered through the type III secretion system to the host cell cytoplasm and nucleus.

3 July 2018

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Evidence that CT694 is a novel Chlamydia trachomatis T3S substrate capable of functioning during invasion or early cycle development

3 July 2018

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Structural basis for activation and inhibition of the secreted chlamydia protease CPAF

3 July 2018

1 reference

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Chlamydia causes fragmentation of the Golgi compartment to ensure reproduction.

3 July 2018

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The host adherens junction molecule nectin-1 is degraded by chlamydial protease-like activity factor (CPAF) in Chlamydia trachomatis-infected genital epithelial cells

3 July 2018

1 reference

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Chlamydial effector proteins localized to the host cell cytoplasmic compartment

3 July 2018

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Actin and intermediate filaments stabilize the Chlamydia trachomatis vacuole by forming dynamic structural scaffolds

3 July 2018

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Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease

3 July 2018

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CD1d degradation in Chlamydia trachomatis-infected epithelial cells is the result of both cellular and chlamydial proteasomal activity

3 July 2018

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The secreted protease factor CPAF is responsible for degrading pro-apoptotic BH3-only proteins in Chlamydia trachomatis-infected cells

3 July 2018

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Analysis of putative Chlamydia trachomatis chaperones Scc2 and Scc3 and their use in the identification of type III secretion substrates.

3 July 2018

1 reference

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A directed screen for chlamydial proteins secreted by a type III mechanism identifies a translocated protein and numerous other new candidates

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5914542

Production of a proteolytically active protein, chlamydial protease/proteasome-like activity factor, by five different Chlamydia species

3 July 2018

1 reference

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Cleavage of host keratin 8 by a Chlamydia-secreted protease

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5914542

A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5914542

Cleavage-dependent activation of a chlamydia-secreted protease

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5914542

Expression and translocation of chlamydial protease during acute and persistent infection of the epithelial HEp-2 cells with Chlamydophila (Chlamydia) pneumoniae

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5914542

Characterization of a secreted Chlamydia protease

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5914542

Chlamydia pneumoniae secretion of a protease-like activity factor for degrading host cell transcription factors required for [correction of factors is required for] major histocompatibility complex antigen expression

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5914542

Identification of a chlamydial protease-like activity factor responsible for the degradation of host transcription factors

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5914542

Secretion of predicted Inc proteins of Chlamydia pneumoniae by a heterologous type III machinery

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5914542

Molecular Koch's postulates applied to microbial pathogenicity

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5914542

The chlamydial protease CPAF: important or not, important for what?

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5914542

Type III secretion system in Chlamydia species: identified members and candidates

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5914542

Molecular Koch's Postulates Applied to Microbial Pathogenicity

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2F2049-632X.12194

21 January 2018

Identifiers

DOI

10.1111/2049-632X.12194

1 reference

1 July 2018

PMCID

5914542

1 reference

1 July 2018

PubMed ID

24942261

1 reference

1 July 2018