Insights into the mechanisms of action of host defence peptides from biophysical and structural investigations (Q37848284)

24 August 2017

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title

Insights into the mechanisms of action of host defence peptides from biophysical and structural investigations (English)

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24 August 2017

Burkhard Bechinger

1

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24 August 2017

28 February 2011

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Journal of Peptide Science

24 August 2017

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24 August 2017

17

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24 August 2017

5

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24 August 2017

306-314

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Synthetic membrane-targeted antibiotics

24 August 2017

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Mechanisms of resistance: useful tool to design antibacterial agents for drug - resistant bacteria

21 January 2018

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Overview on plant antimicrobial peptides.

21 January 2018

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Structural aspects of plant antimicrobial peptides

21 January 2018

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Anti-microbial peptides: from invertebrates to vertebrates.

21 January 2018

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Antimicrobial peptides: premises and promises

21 January 2018

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Antimicrobial peptides of multicellular organisms

21 January 2018

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Antibacterial peptides: basic facts and emerging concepts

21 January 2018

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The roles of antimicrobial peptides in innate host defense

21 January 2018

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Host antimicrobial proteins as endogenous immunomodulators.

21 January 2018

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Structure-activity relationships of multifunctional host defence peptides

21 January 2018

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Multivalent Antimicrobial Peptides as Therapeutics: Design Principles and Structural Diversities

21 January 2018

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Strategies for the discovery and advancement of novel cationic antimicrobial peptides.

21 January 2018

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Cationic amphiphilic peptides with cancer-selective toxicity

21 January 2018

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Novel peptide therapeutics for treatment of infections

21 January 2018

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Structure and functions of channel-forming peptides: magainins, cecropins, melittin and alamethicin

21 January 2018

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Antimicrobial peptides and peptaibols, substitutes for conventional antibiotics

21 January 2018

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Solution NMR studies of amphibian antimicrobial peptides: linking structure to function?

21 January 2018

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A quantitative model for the all-or-none permeabilization of phospholipid vesicles by the antimicrobial peptide cecropin A.

21 January 2018

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Biosynthesis and degradation of peptides derived from Xenopus laevis prohormones

21 January 2018

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Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor

21 January 2018

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Cell-free immunity in insects

21 January 2018

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Anticancer alpha-helical peptides and structure/function relationships underpinning their interactions with tumour cell membranes

21 January 2018

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Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment

21 January 2018

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Dermaseptins and magainins: antimicrobial peptides from frogs' skin-new sources for a promising spermicides microbicides-a mini review

21 January 2018

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Potential therapeutic application of host defense peptides

21 January 2018

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Antimicrobial peptides: natural templates for synthetic membrane-active compounds.

21 January 2018

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Membrane interactions of antimicrobial peptides from Australian frogs

21 January 2018

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Helical membrane peptides to modulate cell function

21 January 2018

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Structure, membrane orientation, mechanism, and function of pexiganan--a highly potent antimicrobial peptide designed from magainin.

21 January 2018

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NMR Structures of the Histidine-Rich Peptide LAH4 in Micellar Environments: Membrane Insertion, pH-Dependent Mode of Antimicrobial Action, and DNA Transfection

21 January 2018

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Antimicrobial mechanism of pore-forming protegrin peptides: 100 pores to kill E. coli

21 January 2018

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Membrane permeabilization by multivalent anti-microbial peptides

21 January 2018

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Antibacterial peptides and mitochondrial presequences affect mitochondrial coupling, respiration and protein import.

21 January 2018

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Magainins and the disruption of membrane-linked free-energy transduction

21 January 2018

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All-D amino acid-containing channel-forming antibiotic peptides

21 January 2018

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The structure, dynamics and orientation of antimicrobial peptides in membranes by multidimensional solid-state NMR spectroscopy

21 January 2018

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Membrane pores induced by magainin

21 January 2018

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Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides

21 January 2018

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Detergent-like actions of linear amphipathic cationic antimicrobial peptides

21 January 2018

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Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?

21 January 2018

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Multifunctional host defense peptides: intracellular-targeting antimicrobial peptides

21 January 2018

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Structure and dynamics of the antibiotic peptide PGLa in membranes by solution and solid-state nuclear magnetic resonance spectroscopy

21 January 2018

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Orientational and aggregational states of magainin 2 in phospholipid bilayers.

21 January 2018

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Optimization of the antimicrobial activity of magainin peptides by modification of charge.

21 January 2018

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Binding of the antibacterial peptide magainin 2 amide to small and large unilamellar vesicles

21 January 2018

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Membrane thinning caused by magainin 2.

21 January 2018

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Interaction of antimicrobial dermaseptin and its fluorescently labeled analogues with phospholipid membranes

21 January 2018

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Solid-state NMR investigation of the membrane-disrupting mechanism of antimicrobial peptides MSI-78 and MSI-594 derived from magainin 2 and melittin

21 January 2018

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Structural determinants of antimicrobial and antiplasmodial activity and selectivity in histidine-rich amphipathic cationic peptides

21 January 2018

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Structure and Membrane Interactions of the Antibiotic Peptide Dermadistinctin K by Multidimensional Solution and Oriented 15N and 31P Solid-State NMR Spectroscopy

21 January 2018

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Membrane structure and conformational changes of the antibiotic heterodimeric peptide distinctin by solid-state NMR spectroscopy.

21 January 2018

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Structure and interactions of magainin antibiotic peptides in lipid bilayers: a solid-state nuclear magnetic resonance investigation

21 January 2018

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Structure and orientation of the antibiotic peptide magainin in membranes by solid-state nuclear magnetic resonance spectroscopy

21 January 2018

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Three-dimensional solid-state NMR spectroscopy of a peptide oriented in membrane bilayers

21 January 2018

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A solid-state NMR index of helical membrane protein structure and topology.

21 January 2018

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Synergistic transmembrane insertion of the heterodimeric PGLa/magainin 2 complex studied by solid-state NMR.

21 January 2018

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Concentration-dependent realignment of the antimicrobial peptide PGLa in lipid membranes observed by solid-state 19F-NMR.

21 January 2018

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Conditions affecting the re-alignment of the antimicrobial peptide PGLa in membranes as monitored by solid state 2H-NMR.

21 January 2018

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Tilt and rotational pitch angle of membrane-inserted polypeptides from combined 15N and 2H solid-state NMR spectroscopy

21 January 2018

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A folding-dependent mechanism of antimicrobial peptide resistance to degradation unveiled by solution structure of distinctin.

21 January 2018

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Towards membrane protein design: pH-sensitive topology of histidine-containing polypeptides

21 January 2018

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Membrane helix orientation from linear dichroism of infrared attenuated total reflection spectra

21 January 2018

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Interactions involved in the realignment of membrane-associated helices. An investigation using oriented solid-state NMR and attenuated total reflection Fourier transform infrared spectroscopies

21 January 2018

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Translocation of amino acyl residues from the membrane interface to the hydrophobic core: thermodynamic model and experimental analysis using ATR-FTIR spectroscopy.

21 January 2018

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Aggregation and membrane permeabilizing properties of designed histidine-containing cationic linear peptide antibiotics.

21 January 2018

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Enhanced membrane disruption and antibiotic action against pathogenic bacteria by designed histidine-rich peptides at acidic pH

21 January 2018

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Membrane order perturbation in the presence of antimicrobial peptides by (2)H solid-state NMR spectroscopy

21 January 2018

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Induction of non-lamellar lipid phases by antimicrobial peptides: a potential link to mode of action

21 January 2018

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Biological activity and structural aspects of PGLa interaction with membrane mimetic systems

21 January 2018

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Antimicrobial lipopolypeptides composed of palmitoyl Di- and tricationic peptides: in vitro and in vivo activities, self-assembly to nanostructures, and a plausible mode of action

21 January 2018

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Helical Peptoid Mimics of Magainin-2 Amide

21 January 2018

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Mimicry of host-defense peptides by unnatural oligomers: antimicrobial beta-peptides

21 January 2018

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Amphiphilic polymethacrylate derivatives as antimicrobial agents

21 January 2018

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Mimicking helical antibacterial peptides with nonpeptidic folding oligomers.

21 January 2018

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Structural determinants of antimicrobial activity in polymers which mimic host defense peptides.

21 January 2018

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De novo designed synthetic mimics of antimicrobial peptides

21 January 2018

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Antimicrobial peptide mimics for improved therapeutic properties

21 January 2018

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Physicochemical determinants for the interactions of magainins 1 and 2 with acidic lipid bilayers.

21 January 2018

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Melittin interaction with sulfated cell surface sugars

21 January 2018

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Membrane insertion and orientation of polyalanine peptides: a (15)N solid-state NMR spectroscopy investigation

21 January 2018

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Solid-state NMR approaches to measure topological equilibria and dynamics of membrane polypeptides

21 January 2018

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The biophysics of peptide models of ion channels

21 January 2018

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Membrane protein folding and stability: physical principles

21 January 2018

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Lipid-alamethicin interactions influence alamethicin orientation

21 January 2018

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Molecular mechanism of antimicrobial peptides: the origin of cooperativity

21 January 2018

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The history of alamethicin: a review of the most extensively studied peptaibol

21 January 2018

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Membrane orientation of the N-terminal segment of alamethicin determined by solid-state 15N NMR

21 January 2018

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Conformation of alamethicin in oriented phospholipid bilayers determined by (15)N solid-state nuclear magnetic resonance

21 January 2018

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Structure and alignment of the membrane-associated peptaibols ampullosporin A and alamethicin by oriented 15N and 31P solid-state NMR spectroscopy

21 January 2018

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15N and 31P solid-state NMR investigations on the orientation of zervamicin II and alamethicin in phosphatidylcholine membranes

21 January 2018

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Mechanism of synergism between antimicrobial peptides magainin 2 and PGLa

21 January 2018

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Synergy among antibacterial peptides and between peptides and small-molecule antibiotics

21 January 2018

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A novel potent strategy for gene delivery using a single peptide vector as a carrier

21 January 2018

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Efficient DNA transfection mediated by the C-terminal domain of human immunodeficiency virus type 1 viral protein R

21 January 2018

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Histidine-rich amphipathic peptide antibiotics promote efficient delivery of DNA into mammalian cells

21 January 2018

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Design and evaluation of histidine-rich amphipathic peptides for siRNA delivery

21 January 2018

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Rational design of vector and antibiotic peptides using solid-state NMR.

21 January 2018

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Optimising histidine rich peptides for efficient DNA delivery in the presence of serum

21 January 2018

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Reversible liposome association induced by LAH4: a peptide with potent antimicrobial and nucleic acid transfection activities

21 January 2018

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Hydramacin-1, structure and antibacterial activity of a protein from the basal metazoan Hydra

21 January 2018

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Molecular self-assembly and applications of designer peptide amphiphiles

21 January 2018

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Solid-State NMR Analysis Comparing the Designer-Made Antibiotic MSI-103 with Its Parent Peptide PGLa in Lipid Bilayers†

21 January 2018

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Synergistic Transmembrane Alignment of the Antimicrobial Heterodimer PGLa/Magainin

21 January 2018

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Functional Synergism of the Magainins PGLa and Magainin-2 in Escherichia coli, Tumor Cells and Liposomes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PSC.1343

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24 August 2017

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PubMed ID

21360627