Metabolic remodelling in human heart failure (Q37849446)

24 August 2017

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title

Metabolic remodelling in human heart failure (English)

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24 August 2017

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Juhani Knuuti

2

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author name string

Helena Tuunanen

series ordinal

1

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24 August 2017

3 March 2011

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24 August 2017

Cardiovascular Research

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24 August 2017

90

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24 August 2017

2

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24 August 2017

251-257

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Guidelines for the diagnosis and treatment of chronic heart failure

24 August 2017

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https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

The adrenergic-fatty acid load in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Cardiac and skeletal muscle insulin resistance in patients with coronary heart disease. A study with positron emission tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Glucose uptake in the chronically dysfunctional but viable myocardium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Myocardial perfusion reserve and oxidative metabolism contribute to exercise capacity in patients with dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Morbidity and mortality in diabetics in the Framingham population. Sixteen year follow-up study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Diabetes mellitus and congestive heart failure. Further knowledge needed

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Insulin resistance in idiopathic dilated cardiomyopathy: a possible etiologic link

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Insulin resistance and risk of congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Metabolic mechanisms in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Adaptation and maladaptation of the heart in diabetes: Part I: general concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Enalapril reduces the incidence of diabetes in patients with chronic heart failure: insight from the Studies Of Left Ventricular Dysfunction (SOLVD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Celiprolol augments the effect of physical exercise on insulin sensitivity and serum lipid levels in chronic heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Effect of selective and nonselective beta-blockers on resting energy production rate and total body substrate utilization in chronic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Carvedilol does not alter the insulin sensitivity in patients with congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Glucose metabolism and left ventricular dysfunction are normalized by insulin and islet transplantation in mild diabetes in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Glycemic control and heart failure among adult patients with diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Impaired insulin sensitivity as an independent risk factor for mortality in patients with stable chronic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Prognostic importance of insulin-mediated glucose uptake in aged patients with congestive heart failure secondary to mitral and/or aortic valve disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Obesity and the risk of heart failure

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Plasma adiponectin, body mass index, and mortality in patients with chronic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Hypothesis concerning the U-shaped relation between body mass index and mortality

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Myocardial substrate metabolism in the normal and failing heart

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Glucose-free fatty acid cycle operates in human heart and skeletal muscle in vivo

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Impact of aging on substrate metabolism by the human heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Energy metabolism of the heart: from basic concepts to clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

The effect of insulin and FFA on myocardial glucose uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Altered myocardial high-energy phosphate metabolites in patients with dilated cardiomyopathy

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

The failing heart--an engine out of fuel

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

The development of myocardial insulin resistance in conscious dogs with advanced dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Total-body and myocardial substrate oxidation in congestive heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Free fatty acid kinetics and oxidation in congestive heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Abnormalities of whole body protein turnover, muscle metabolism and levels of metabolic hormones in patients with chronic heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Regional myocardial blood flow reserve impairment and metabolic changes suggesting myocardial ischemia in patients with idiopathic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Moderate severity heart failure does not involve a downregulation of myocardial fatty acid oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Metabolic gene expression in fetal and failing human heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Characterization of altered myocardial fatty acid metabolism in patients with inherited cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Myocardial perfusion reserve and peripheral endothelial function in patients with idiopathic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Myocardial efficiency during levosimendan infusion in congestive heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Allopurinol improves myocardial efficiency in patients with idiopathic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Effect of metoprolol on myocardial function and energetics in patients with nonischemic dilated cardiomyopathy: a randomized, double-blind, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Selective versus nonselective beta-adrenergic receptor blockade in chronic heart failure: differential effects on myocardial energy substrate utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Effect of carvedilol on microcirculatory and glucose metabolic regulation in patients with congestive heart failure secondary to ischemic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Influence of insulin and free fatty acids on contractile function in patients with chronically stunned and hibernating myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Suppression of circulating free fatty acids with acipimox in chronic heart failure patients changes whole body metabolism but does not affect cardiac function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Free fatty acid depletion acutely decreases cardiac work and efficiency in cardiomyopathic heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Effects of trimetazidine on the contractile response of chronically dysfunctional myocardium to low-dose dobutamine in ischaemic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Long term cardioprotective action of trimetazidine and potential effect on the inflammatory process in patients with ischaemic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Effects of metabolic modulation by trimetazidine on left ventricular function and phosphocreatine/adenosine triphosphate ratio in patients with heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Glycoprotein IIb/IIIa inhibitors in patients with unstable angina/non-ST–segment elevation myocardial infarction: Appropriate interpretation of the guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Effects of trimetazidine on ischemic left ventricular dysfunction in patients with coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Trimetazidine improves left ventricular function in diabetic patients with coronary artery disease: a double-blind placebo-controlled study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Trimetazidine improves left ventricular function and quality of life in elderly patients with coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Trimetazidine, a metabolic modulator, has cardiac and extracardiac benefits in idiopathic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

A randomized clinical trial of trimetazidine, a partial free fatty acid oxidation inhibitor, in patients with heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Effects of trimetazidine on myocardial perfusion and the contractile response of chronically dysfunctional myocardium in ischemic cardiomyopathy: a 24-month study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Myocardial insulin resistance associated with chronic hypertriglyceridemia and increased FFA levels in Type 2 diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Multi-centre experience on the use of perhexiline in chronic heart failure and refractory angina: old drug, new hope

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Effects of perhexiline on myocardial deformation in patients with ischaemic left ventricular dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

A double-blind randomized multicentre clinical trial to evaluate the efficacy and safety of two doses of etomoxir in comparison with placebo in patients with moderate congestive heart failure: the ERGO (etomoxir for the recovery of glucose oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Body composition and prognosis in chronic systolic heart failure: the obesity paradox

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Decreased Myocardial Free Fatty Acid Uptake in Patients With Idiopathic Dilated Cardiomyopathy: Evidence of Relationship With Insulin Resistance and Left Ventricular Dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

Elevated Levels of 8-iso-Prostaglandin F 2α in Pericardial Fluid of Patients With Heart Failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR052

21 January 2018

Identifiers

DOI

10.1093/CVR/CVR052

1 reference

24 August 2017

1 reference

PubMed ID

21372005