Designing oral vaccines targeting intestinal dendritic cells (Q37849779)

24 August 2017

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title

Designing oral vaccines targeting intestinal dendritic cells (English)

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24 August 2017

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2

Bruno G De Geest

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24 August 2017

Bert Devriendt

1

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24 August 2017

Eric Cox

series ordinal

3

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24 August 2017

language of work or name

English

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publication date

5 March 2011

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Expert Opinion on Drug Delivery

24 August 2017

published in

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24 August 2017

volume

8

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24 August 2017

issue

4

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24 August 2017

page(s)

467-483

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Vaccination strategies for mucosal immune responses

24 August 2017

cites work

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Perspectives on mucosal vaccines: is mucosal tolerance a barrier?

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Mucosal dendritic cells in immunity and inflammation

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New trends in antigen uptake in the gut mucosa

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The multifaceted influence of the mucosal microflora on mucosal dendritic cell responses

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M-cells: origin, morphology and role in mucosal immunity and microbial pathogenesis.

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Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: implications for microbial attachment and oral vaccine targeting

21 January 2018

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Transient expression of M-cell phenotype by enterocyte-like cells of the follicle-associated epithelium of mouse Peyer's patches

21 January 2018

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Antigen sampling across epithelial barriers and induction of mucosal immune responses

21 January 2018

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Intestinal villous M cells: an antigen entry site in the mucosal epithelium

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M-cells are damaged and increased in number in inflamed human ileal mucosa

21 January 2018

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Antigen transport into Peyer's patches: increased uptake by constant numbers of M cells

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Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

21 January 2018

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Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement

21 January 2018

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CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

21 January 2018

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Phenotype and distribution of dendritic cells in the porcine small intestinal and tracheal mucosa and their spatial relationship to epithelial cells.

21 January 2018

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Characterization of the porcine neonatal Fc receptor--potential use for trans-epithelial protein delivery

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Peyer's patch dendritic cells process viral antigen from apoptotic epithelial cells in the intestine of reovirus-infected mice

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Transcytosis of cholera toxin subunits across model human intestinal epithelia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

The oral absorption of micro- and nanoparticulates: neither exceptional nor unusual

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Transcytosis of F4 fimbriae by villous and dome epithelia in F4-receptor positive pigs supports importance of receptor-dependent endocytosis in oral immunization strategies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Immunobiology of dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

21 January 2018

Mucosal dendritic cells

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Antigen presentation and T cell stimulation by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Dendritic cell subsets in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Intestinal dendritic cells increase T cell expression of alpha4beta7 integrin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Essential role for CD103 in the T cell-mediated regulation of experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Dendritic cells in intestinal immune regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Dendritic cells in intestinal homeostasis and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Recent progress in understanding the phenotype and function of intestinal dendritic cells and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Origin of the lamina propria dendritic cell network

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Intestinal lamina propria dendritic cell subsets have different origin and functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alpha E beta 7 integrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Generation of gut-homing T cells and their localization to the small intestinal mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

The porcine dendritic cell family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Isolation and characterisation of pig Peyer's patch dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Dendritic cells interact with CD4 T cells in intestinal mucosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Workshop studies on monoclonal antibodies in the myeloid panel with CD11 specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Characterization of conventional and plasmacytoid dendritic cells in swine secondary lymphoid organs and blood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Retinoic acid imprints gut-homing specificity on T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Intestinal inflammation abrogates the tolerogenic properties of MLN CD103+ dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Enteric flora expands gut lamina propria CX3CR1+ dendritic cells supporting inflammatory immune responses under normal and inflammatory conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

The diverse ontogeny and function of murine small intestinal dendritic cell/macrophage subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Transforming growth factor-beta induces development of the T(H)17 lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

ATP drives lamina propria T(H)17 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

IL-10-dependent partial refractoriness to Toll-like receptor stimulation modulates gut mucosal dendritic cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

The food contaminant fumonisin B(1) reduces the maturation of porcine CD11R1(+) intestinal antigen presenting cells and antigen-specific immune responses, leading to a prolonged intestinal ETEC infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

The biology of intestinal immunoglobulin A responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Expression of TECK/CCL25 and MEC/CCL28 chemokines and their respective receptors CCR9 and CCR10 in porcine mucosal tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

The yin and yang of intestinal epithelial cells in controlling dendritic cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Steady-state and inflammatory dendritic-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Innate immune recognition at the epithelial barrier drives adaptive immunity: APCs take the back seat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Enterotoxigenic Escherichia coli (K88) induce proinflammatory responses in porcine intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Directed cell migration via chemoattractants released from degradable microspheres.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Essential role of antigen-presenting cell-derived BAFF for antibody responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Recognition of microorganisms and activation of the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Pattern recognition receptors: doubling up for the innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Improving vaccines by targeting antigens to dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

In vivo targeting of antigens to human dendritic cells through DC-SIGN elicits stimulatory immune responses and inhibits tumor growth in grafted mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Engineered lentivector targeting of dendritic cells for in vivo immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Siglecs and their roles in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Sialoadhesin-deficient mice exhibit subtle changes in B- and T-cell populations and reduced immunoglobulin M levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Involvement of sialoadhesin in entry of porcine reproductive and respiratory syndrome virus into porcine alveolar macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Targeting to porcine sialoadhesin receptor improves antigen presentation to T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Mannan derivatives induce phenotypic and functional maturation of mouse dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Targeting nanoparticles to M cells with non-peptidic ligands for oral vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Liposomal meningococcal B vaccination: role of dendritic cell targeting in the development of a protective immune response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Liposomal delivery of antigen to human dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Protection against Leishmania major infection by oligomannose-coated liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Bioadhesive mannosylated nanoparticles for oral drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Delivery of multiple epitopes by recombinant detoxified adenylate cyclase of Bordetella pertussis induces protective antiviral immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Dendritic cell targeting of Bacillus anthracis protective antigen expressed by Lactobacillus acidophilus protects mice from lethal challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Induction of protective immunity against microbial challenge by targeting antigens expressed by probiotic bacteria to mucosal dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Vaccines that facilitate antigen entry into dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Fc receptors in livestock species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

FcgammaRIV: a novel FcR with distinct IgG subclass specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Fc receptor-targeted mucosal vaccination as a novel strategy for the generation of enhanced immunity against mucosal and non-mucosal pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

F(c)gammaRI-targeted fusion proteins result in efficient presentation by human monocytes of antigenic and antagonist T cell epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Regulation of antibody responses via antibodies, complement, and Fc receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Utilization of Fc receptors as a mucosal vaccine strategy against an intracellular bacterium, Francisella tularensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Targeting of Escherichia coli F4 fimbriae to Fcgamma receptors enhances the maturation of porcine dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

A critical role for Syk protein tyrosine kinase in Fc receptor-mediated antigen presentation and induction of dendritic cell maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

A novel Syk kinase-selective inhibitor blocks antigen presentation of immune complexes in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Modulation of dendritic cell maturation and function by B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Dependence of antibody-mediated presentation of antigen on FcRn

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

The MHC class II-associated invariant chain interacts with the neonatal Fc gamma receptor and modulates its trafficking to endosomal/lysosomal compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Immunization with pseudorabies virus harboring Fc domain of IgG makes a contribution to protection of mice from lethal challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Fcgamma receptors as regulators of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

FcgammaRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Fcgamma receptors are crucial for the expression of acquired resistance to virulent Salmonella enterica serovar Typhimurium in vivo but are not required for the induction of humoral or T-cell-mediated immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

How intestinal epithelial cells tolerise dendritic cells and its relevance to inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Porcine dendritic cells generated in vitro: morphological, phenotypic and functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Intestinal Bacteria Trigger T Cell-Independent Immunoglobulin A2 Class Switching by Inducing Epithelial-Cell Secretion of the Cytokine APRIL

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

In Vivo Targeting of DC-SIGN-positive Antigen-presenting Cells in a Nonhuman Primate Model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561312

10.1517/17425247.2011.561312

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference