Viruses and the human DEAD-box helicase DDX3: inhibition or exploitation? (Q37856429)

24 August 2017

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title

Viruses and the human DEAD-box helicase DDX3: inhibition or exploitation? (English)

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24 August 2017

Martina Schröder

1

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24 August 2017

1 April 2011

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Biochemical Society Transactions

24 August 2017

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24 August 2017

39

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24 August 2017

2

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24 August 2017

679-683

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Assignment of a human putative RNA helicase gene, DDX3, to human X chromosome bands p11.3-->p11.23

24 August 2017

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

DEAD-box proteins: the driving forces behind RNA metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Human DEAD-box protein 3 has multiple functions in gene regulation and cell cycle control and is a prime target for viral manipulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Cellular cofactors affecting hepatitis C virus infection and replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Viral and cellular RNA helicases as antiviral targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

DDX3, a DEAD box RNA helicase with tumor growth-suppressive property and transcriptional regulation activity of the p21waf1/cip1 promoter, is a candidate tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Oncogenic role of DDX3 in breast cancer biogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Human DEAD-box ATPase DDX3 shows a relaxed nucleoside substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Human cytomegalovirus induces the interferon response via the DNA sensor ZBP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKepsilo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

IFI16 is an innate immune sensor for intracellular DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

DDX3 DEAD-Box RNA helicase inhibits hepatitis B virus reverse transcription by incorporation into nucleocapsids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

DDX3, a DEAD box RNA helicase, is deregulated in hepatitis virus-associated hepatocellular carcinoma and is involved in cell growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Hepatitis C virus core protein binds to a DEAD box RNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Hepatitis C virus core protein interacts with a human DEAD box protein DDX3

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Hepatitis C virus core-derived peptides inhibit genotype 1b viral genome replication via interaction with DDX3X

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Knockdown of cellular RNA helicase DDX3 by short hairpin RNAs suppresses HIV-1 viral replication without inducing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Pharmacophore modeling and molecular docking led to the discovery of inhibitors of human immunodeficiency virus-1 replication targeting the human cellular aspartic acid-glutamic acid-alanine-aspartic acid box polypeptide 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

Ring Expanded Nucleoside Analogues Inhibit RNA Helicase and Intracellular Human Immunodeficiency Virus Type 1 Replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390679

21 January 2018

Identifiers

DOI

10.1042/BST0390679

1 reference

24 August 2017

1 reference

PubMed ID

21428961