MLL1/WDR5 complex in leukemogenesis and epigenetic regulation. (Q37857936)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21439245%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

review article

2 references

23 August 2022

MLL1/WDR5 complex in leukemogenesis and epigenetic regulation (English)

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26 January 2020

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proto-oncogene protein

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2 August 2019

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22 December 2019

Min Wu

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26 January 2020

Hong-Bing Shu

series ordinal

2

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23 August 2022

Chinese Journal of Cancer

8 references

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2 August 2019

28 September 2019

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4

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240-246

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Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

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copyright license

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on focus list of Wikimedia project

23 August 2022

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copyrighted

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cites work

Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis

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AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia

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Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.

6 September 2017

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6 September 2017

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WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket

6 September 2017

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Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide

6 September 2017

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The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide

6 September 2017

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Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation

6 September 2017

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CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes

6 September 2017

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RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

6 September 2017

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MLL translocations, histone modifications and leukaemia stem-cell development

6 September 2017

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Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4

6 September 2017

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Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression

6 September 2017

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Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF

6 September 2017

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6 September 2017

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A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling

6 September 2017

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ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression

6 September 2017

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Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development

6 September 2017

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MLL associates specifically with a subset of transcriptionally active target genes

6 September 2017

1 reference

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Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

6 September 2017

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6 September 2017

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Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation

6 September 2017

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Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization

6 September 2017

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COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression

6 September 2017

1 reference

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COMPASS: a complex of proteins associated with a trithorax-related SET domain protein

6 September 2017

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The TFIID components human TAF(II)140 and Drosophila BIP2 (TAF(II)155) are novel metazoan homologues of yeast TAF(II)47 containing a histone fold and a PHD finger

6 September 2017

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Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.

6 September 2017

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Altered Hox expression and segmental identity in Mll-mutant mice

6 September 2017

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Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias

6 September 2017

1 reference

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Bimodal degradation of MLL by SCFSkp2 and APCCdc20 assures cell cycle execution: a critical regulatory circuit lost in leukemogenic MLL fusions

6 September 2017

1 reference

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A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit.

28 September 2017

1 reference

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WDR5, a complexed protein.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013350

Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013350

ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013350

E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013350

Dimerization of MLL fusion proteins immortalizes hematopoietic cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013350

1 September 2018

Identifiers

DOI

10.5732/CJC.011.10055

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21439245%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21439245%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

21439245

1 reference