Cellular and molecular mechanisms of vascular injury in diabetes--part II: cellular mechanisms and therapeutic targets (Q37859918)

24 August 2017

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title

Cellular and molecular mechanisms of vascular injury in diabetes--part II: cellular mechanisms and therapeutic targets (English)

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24 August 2017

2

Raffaele De Caterina

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24 August 2017

Rosalinda Madonna

1

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24 August 2017

29 March 2011

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24 August 2017

Vascular Pharmacology

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24 August 2017

54

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24 August 2017

75-79

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24 August 2017

3-6

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Human adult vena saphena contains perivascular progenitor cells endowed with clonogenic and proangiogenic potential

24 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

A review of the GUARDIAN trial results: clinical implications and the significance of elevated perioperative CK-MB on 6-month survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Osmotic shock inhibits insulin signaling by maintaining Akt/protein kinase B in an inactive dephosphorylated state

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Inhibition of balloon injury-induced neointimal formation by olmesartan and pravastatin in rats with insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Effects of insulin resistance on endothelial progenitor cells and vascular repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Endothelial dysfunctions: common denominators in vascular disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Vascular repair by circulating endothelial progenitor cells: the missing link in atherosclerosis?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

[Anti-oxidants, controversies and perspectives: how can the failure of clinical studies using anti-oxidants be explained?]

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Generalised reduction of putative endothelial progenitors and CXCR4-positive peripheral blood cells in type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Circulating endothelial progenitor cells are reduced in peripheral vascular complications of type 2 diabetes mellitus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Diabetes impairs progenitor cell mobilisation after hindlimb ischaemia–reperfusion injury in rats

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Glucose tolerance is negatively associated with circulating progenitor cell levels.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Time course and mechanisms of circulating progenitor cell reduction in the natural history of type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Oxidative stress in response to high glucose levels in endothelial cells and in endothelial progenitor cells: evidence for differential glutathione peroxidase-1 expression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Effects of propionyl-L-carnitine on isolated mitochondrial function in the reperfused diabetic rat heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1 alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Positive and negative regulation of glucose uptake by hyperosmotic stress

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Peroxisome proliferator-activated receptor-delta agonist enhances vasculogenesis by regulating endothelial progenitor cells through genomic and nongenomic activations of the phosphatidylinositol 3-kinase/Akt pathway.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Endothelial progenitor thrombospondin-1 mediates diabetes-induced delay in reendothelialization following arterial injury.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Vessel wall-derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

From bone marrow to the arterial wall: the ongoing tale of endothelial progenitor cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Hyperosmotic stress stimulates tissue plasminogen activator expression by a PKC-independent pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Endothelial Progenitor Cell Dysfunction: A Novel Concept in the Pathogenesis of Vascular Complications of Type 1 Diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Adipose tissue-derived stem cells: characterization and potential for cardiovascular repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

In vitro neovasculogenic potential of resident adipose tissue precursors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Cellular and molecular mechanisms of vascular injury in diabetes--part I: pathways of vascular disease in diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Insulin enhances vascular cell adhesion molecule-1 expression in human cultured endothelial cells through a pro-atherogenic pathway mediated by p38 mitogen-activated protein-kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

The prominent role of p38 mitogen-activated protein kinase in insulin-mediated enhancement of VCAM-1 expression in endothelial cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

NA+/H+ exchanger 1- and aquaporin-1-dependent hyperosmolarity changes decrease nitric oxide production and induce VCAM-1 expression in endothelial cells exposed to high glucose.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Age-dependent impairment of number and angiogenic potential of adipose tissue-derived progenitor cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Antioxidant vitamins and prevention of cardiovascular disease: epidemiological and clinical trial data

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Improvement of postnatal neovascularization by human adipose tissue-derived stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Effects of the superoxide dismutase-mimetic compound tempol on endothelial dysfunction in streptozotocin-induced diabetic rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Effects of antioxidant supplementation on postprandial oxidative stress and endothelial dysfunction: a single-blind, 15-day clinical trial in patients with untreated type 2 diabetes, subjects with impaired glucose tolerance, and healthy controls.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Molecular aspects of lipoic acid in the prevention of diabetes complications

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Endothelial progenitor cells--an evolving story

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

PPARgamma-agonist rosiglitazone increases number and migratory activity of cultured endothelial progenitor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Aging, progenitor cell exhaustion, and atherosclerosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Oxidative stress and cardiovascular disease: antioxidants and unresolved issues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Insulin resistance induced by loop diuretics and hyperosmolarity in perfused rat liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

p38 mitogen-activated protein kinase downregulates endothelial progenitor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: restoration by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Diabetes and vessel wall remodelling: from mechanistic insights to regenerative therapies.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Glitazones: clinical effects and molecular mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Endothelial dysfunction in impaired fasting glycemia, impaired glucose tolerance, and type 2 diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Anti-oxidants for therapeutic use: why are only a few drugs in clinical use?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Design of a trial evaluating myocardial cell protection with cariporide, an inhibitor of the transmembrane sodium-hydrogen exchanger: the Guard During Ischemia Against Necrosis (GUARDIAN) trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Role of inflammation and oxidative stress in endothelial progenitor cell function and mobilization: therapeutic implications for cardiovascular diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Role of microRNAs in vascular diseases, inflammation, and angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Vitamin E supplementation and cardiovascular events in high-risk patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Vascular wall resident progenitor cells: a source for postnatal vasculogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

SDF-1alpha/CXCR4 decreases endothelial progenitor cells apoptosis under serum deprivation by PI3K/Akt/eNOS pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

Hyperosmolality induces activation of cPKC and nPKC, a requirement for ERK1/2 activation in NIH/3T3 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2011.03.007

10.1016/J.VPH.2011.03.007

7 January 2021

Identifiers

DOI

1 reference

24 August 2017

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PubMed ID

21453785