Urease inhibitors as potential drugs for gastric and urinary tract infections: a patent review (Q37860345)

24 August 2017

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title

Urease inhibitors as potential drugs for gastric and urinary tract infections: a patent review (English)

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24 August 2017

urinary tract infection

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Paulina Kosikowska

1

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Łukasz Berlicki

object named as

Łukasz Berlicki

series ordinal

2

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language of work or name

English

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publication date

4 April 2011

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Expert Opinion on Therapeutic Patents

24 August 2017

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24 August 2017

21

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24 August 2017

6

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24 August 2017

945-957

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Ureases I. Functional, catalytic and kinetic properties: A review

24 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

The burden borne by urease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

The hydrolysis of urea and the proficiency of urease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

70 Years of Crystalline Urease: What Have We Learned?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Chemistry and mechanism of urease inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

A new proposal for urease mechanism based on the crystal structures of the native and inhibited enzyme from Bacillus pasteurii: why urea hydrolysis costs two nickels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

The crystal structure of urease from Klebsiella aerogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

The complex of Bacillus pasteurii urease with acetohydroxamate anion from X-ray data at 1.55 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Insights into the role and structure of plant ureases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Macromolecular assembly of Helicobacter pylori urease investigated by mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Evidence that the adverse effect of urea fertilizer on seed germination in soil is due to ammonia formed through hydrolysis of urea by soil urease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Complicated catheter-associated urinary tract infections due to Escherichia coli and Proteus mirabilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Colonization and infection by Helicobacter pylori in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Ureases as a target for the treatment of gastric and urinary infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Helicobacter pylori virulence and genetic geography

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Acid survival of Helicobacter pylori: how does urease activity trigger cytoplasmic pH homeostasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

The role of internal urease in acid resistance of Helicobacter pylori.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Supramolecular assembly and acid resistance of Helicobacter pylori urease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Evidence for the presence of urease apoprotein complexes containing UreD, UreF, and UreG in cells that are competent for in vivo enzyme activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Expression of the Helicobacter pylori ureI gene is required for acidic pH activation of cytoplasmic urease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Acid resistance of Helicobacter pylori depends on the UreI membrane protein and an inner membrane proton barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Bacterial ureases in infectious diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

21 January 2018

Urinary infection stones

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Role of Urease in Pyelonephritis Resulting from Urinary Tract Infection with Proteus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Uncomplicated urinary tract infection in adults including uncomplicated pyelonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Structure-activity correlations between hydroxamic acids and their inhibitory powers on urease activity. I. A quantitative approach to the effect of hydrophobic character of acyl residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Inhibition of urease activity by hydroxamic acid derivatives of amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Therapy for urolithiasis by hydroxamic acids. II. Urease inhibitory potency and urinary excretion rate of hippurohydroxamic acid derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Mutagenicity of N-acylglycinohydroxamic acids and related compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Therapy for urolithiasis by hydroxamic acids. III. Urease inhibitory potency and urinary excretion rate of N-acylglycinohydroxamic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Treatment of infected urinary stones in rats by a new hydroxamic acid, "N-(pivaloyl)glycinohydroxamic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Inhibition of Jack Bean urease (EC 3.5.1.5) by acetohydroxamic acid and by phosphoramidate. An equivalent weight for urease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Design, synthesis, and evaluation of novel organophosphorus inhibitors of bacterial ureases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Computer-aided optimization of phosphinic inhibitors of bacterial ureases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

N-substituted hydroxyureas as urease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Facile one-pot synthesis of thio and selenourea derivatives: a new class of potent urease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Inhibition of jack bean urease by 1,4-benzoquinone and 2,5-dimethyl-1,4-benzoquinone. Evaluation of the inhibition mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Urease inhibitory activity of simple alpha,beta-unsaturated ketones

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Polyhalogenated benzo- and naphthoquinones are potent inhibitors of plant and bacterial ureases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Alpha-hydroxyketones as inhibitors of urease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

The synthesis, structure and activity evaluation of pyrogallol and catechol derivatives as Helicobacter pylori urease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Novel therapeutic approaches to gastric and duodenal ulcers: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Potent inhibitory action of the gastric proton pump inhibitor lansoprazole against urease activity of Helicobacter pylori: unique action selective for H. pylori cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Kinetics of novel competitive inhibitors of urease enzymes by a focused library of oxadiazoles/thiadiazoles and triazoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Synthesis, molecular docking and biological evaluation of Schiff base transition metal complexes as potential urease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

Synthesis, structures, and urease inhibitory activities of three copper(II) and zinc(II) complexes with 2-{[2-(2-hydroxyethylamino)ethylimino]methyl}-4-nitrophenol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.574615

10.1517/13543776.2011.574615

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21457123