Multifunctional cationic host defence peptides and their clinical applications (Q37875767)

24 August 2017

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title

Multifunctional cationic host defence peptides and their clinical applications (English)

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24 August 2017

Shaan L Gellatly

2

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Robert E. W. Hancock

series ordinal

3

object named as

Robert E W Hancock

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24 August 2017

Amy T Y Yeung

1

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24 August 2017

publication date

15 May 2011

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Cellular and Molecular Life Sciences

24 August 2017

published in

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24 August 2017

volume

68

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24 August 2017

issue

13

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24 August 2017

page(s)

2161-2176

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Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells

24 August 2017

cites work

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Multifunctional host defense peptides: antiparasitic activities

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RDP58 is a novel and potentially effective oral therapy for ulcerative colitis.

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An angiogenic role for the human peptide antibiotic LL-37/hCAP-18.

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Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment

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Cutaneous wound healing

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Suppression of human prostate tumor growth in mice by a cytolytic D-, L-amino Acid Peptide: membrane lysis, increased necrosis, and inhibition of prostate-specific antigen secretion

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DNA vaccines encoding human immunodeficiency virus-1 glycoprotein 120 fusions with proinflammatory chemoattractants induce systemic and mucosal immune responses

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A multinational, randomized phase III trial of iseganan HCl oral solution for reducing the severity of oral mucositis in patients receiving radiotherapy for head-and-neck malignancy.

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Cationic peptides: a new source of antibiotics

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12 December 2020

Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency

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12 December 2020

Intracellular receptor for human host defense peptide LL-37 in monocytes

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12 December 2020

Host defense peptides in wound healing.

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12 December 2020

Endogenous antimicrobial peptides and skin infections in atopic dermatitis

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12 December 2020

Antifungal peptides: novel therapeutic compounds against emerging pathogens

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12 December 2020

Antibacterial peptides for therapeutic use: obstacles and realistic outlook

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12 December 2020

Mechanism of action of the antimicrobial peptide buforin II: buforin II kills microorganisms by penetrating the cell membrane and inhibiting cellular functions

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12 December 2020

Production of a cytotoxic cationic antibacterial peptide in Escherichia coli using SUMO fusion partner.

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12 December 2020

Cell-targeting and cell-penetrating peptides for delivery of therapeutic and imaging agents

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12 December 2020

MSI-78, an Analogue of the Magainin Antimicrobial Peptides, Disrupts Lipid Bilayer Structure via Positive Curvature Strain

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12 December 2020

Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens

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12 December 2020

Intracellular transduction using cell-penetrating peptides

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12 December 2020

Innate immunity and new adjuvants.

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12 December 2020

Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor

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12 December 2020

Interaction of antimicrobial dermaseptin and its fluorescently labeled analogues with phospholipid membranes

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12 December 2020

The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics

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12 December 2020

Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria

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12 December 2020

An antimicrobial peptide, magainin 2, induced rapid flip-flop of phospholipids coupled with pore formation and peptide translocation.

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12 December 2020

From "carpet" mechanism to de-novo designed diastereomeric cell-selective antimicrobial peptides

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12 December 2020

Bovine lactoferrin peptidic fragments involved in inhibition of Echovirus 6 in vitro infection

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12 December 2020

Effect of drastic sequence alteration and D-amino acid incorporation on the membrane binding behavior of lytic peptides

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12 December 2020

Cationic host defense (antimicrobial) peptides

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12 December 2020

Novel alpha-melanocyte stimulating hormone peptide analogues with high candidacidal activity

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12 December 2020

Dual functions of the human antimicrobial peptide LL-37-target membrane perturbation and host cell cargo delivery

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12 December 2020

Electrically gated ionic channels in lipid bilayers

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12 December 2020

Mechanisms for induction of acquired host immunity by neutrophil peptide defensins

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12 December 2020

CD-NP, a chimeric natriuretic peptide for the treatment of heart failure.

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12 December 2020

Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens

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12 December 2020

Use of artificial intelligence in the design of small peptide antibiotics effective against a broad spectrum of highly antibiotic-resistant superbugs

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12 December 2020

Antimicrobial peptide hLF1-11 directs granulocyte-macrophage colony-stimulating factor-driven monocyte differentiation toward macrophages with enhanced recognition and clearance of pathogens

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12 December 2020

Deficiency of antibacterial peptides in patients with morbus Kostmann: an observation study.

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12 December 2020

Impact of LL-37 on anti-infective immunity.

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12 December 2020

Structure and mechanism of action of an indolicidin peptide derivative with improved activity against gram-positive bacteria

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12 December 2020

The cationic antimicrobial peptide LL-37 modulates dendritic cell differentiation and dendritic cell-induced T cell polarization

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12 December 2020

AP214, an analogue of alpha-melanocyte-stimulating hormone, ameliorates sepsis-induced acute kidney injury and mortality

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12 December 2020

Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense

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12 December 2020

Mechanism of lipid bilayer disruption by the human antimicrobial peptide, LL-37.

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12 December 2020

Cationic host defence peptides: innate immune regulatory peptides as a novel approach for treating infections.

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12 December 2020

Antimicrobial peptides of multicellular organisms

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12 December 2020

Conformation-dependent antibacterial activity of the naturally occurring human peptide LL-37

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12 December 2020

The effect of bovine lactoferrin and lactoferricin B on the ability of feline calicivirus (a norovirus surrogate) and poliovirus to infect cell cultures

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12 December 2020

Mechanism of antimicrobial action of indolicidin

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12 December 2020

Design of novel peptide analogs with potent fungicidal activity, based on PMAP-23 antimicrobial peptide isolated from porcine myeloid

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12 December 2020

The role of cationic antimicrobial peptides in innate host defences

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12 December 2020

A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity

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12 December 2020

Peptide antimicrobial agents

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12 December 2020

Potential of immunomodulatory host defense peptides as novel anti-infectives

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12 December 2020

Host defense peptides as effector molecules of the innate immune response: a sledgehammer for drug resistance?

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12 December 2020

Topical versus systemic antimicrobial therapy for treating mildly infected diabetic foot ulcers: a randomized, controlled, double-blinded, multicenter trial of pexiganan cream

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12 December 2020

Antimicrobial peptides with stability toward tryptic degradation.

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12 December 2020

Design, synthesis, and actions of a novel chimeric natriuretic peptide: CD-NP.

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12 December 2020

Correlation of binding of rabbit granulocyte peptides to Candida albicans with candidacidal activity

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12 December 2020

Killing of trypanosomatid parasites by a modified bovine host defense peptide, BMAP-18

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12 December 2020

Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment

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12 December 2020

Alternative mechanisms of action of cationic antimicrobial peptides on bacteria

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12 December 2020

Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus

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12 December 2020

Insulin-like growth factors I and II expression in the healing wound

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12 December 2020

Therapeutic potential of HDPs as immunomodulatory agents

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12 December 2020

The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system.

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12 December 2020

Expression and regulation of antimicrobial peptides in the gastrointestinal tract

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12 December 2020

Inducible and constitutive beta-defensins are differentially expressed in Crohn's disease and ulcerative colitis.

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12 December 2020

Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli

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12 December 2020

The antimicrobial peptide dermaseptin S4 inhibits HIV-1 infectivity in vitro

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12 December 2020

An anti-infective peptide that selectively modulates the innate immune response

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12 December 2020

The role of antimicrobial peptides in animal defenses

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12 December 2020

Antimicrobial peptide resistance mechanisms of human bacterial pathogens.

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12 December 2020

Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide.

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12 December 2020

Augmentation of innate host defense by expression of a cathelicidin antimicrobial peptide.

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12 December 2020

The roles of cathelicidin LL-37 in immune defences and novel clinical applications

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12 December 2020

Efficacy of hexapeptide-7 on menopausal skin

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12 December 2020

Effect of antibacterial cathelicidin peptide CAP18/LL-37 on sepsis in neonatal rats.

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12 December 2020

Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors

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12 December 2020

Cationic amphiphilic peptides with cancer-selective toxicity

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12 December 2020

Mammalian defensins in immunity: more than just microbicidal

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12 December 2020

Host defence peptides from invertebrates--emerging antimicrobial strategies

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12 December 2020

CpG oligonucleotide, host defense peptide and polyphosphazene act synergistically, inducing long-lasting, balanced immune responses in cattle

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12 December 2020

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

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12 December 2020

Cost-effective expression and purification of antimicrobial and host defense peptides in Escherichia coli.

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12 December 2020

Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

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12 December 2020

Barrel-stave model or toroidal model? A case study on melittin pores.

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12 December 2020

A re-evaluation of the role of host defence peptides in mammalian immunity.

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12 December 2020

Antinematodal effect of antimicrobial peptide, PMAP-23, isolated from porcine myeloid against Caenorhabditis elegans

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12 December 2020

A cathelicidin family of human antibacterial peptide LL-37 induces mast cell chemotaxis

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12 December 2020

Interaction of cationic antimicrobial peptides with model membranes

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12 December 2020

Immunotherapy: past, present and future

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12 December 2020

Pn-AMP1, a plant defense protein, induces actin depolarization in yeasts

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12 December 2020

Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies

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12 December 2020

Mechanism of anticancer activity of buforin IIb, a histone H2A-derived peptide

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12 December 2020

Neutrophil defensins induce histamine secretion from mast cells: mechanisms of action

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12 December 2020

LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells

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12 December 2020

Cationic peptides: effectors in innate immunity and novel antimicrobials

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12 December 2020

Alternative splicing determines the binding of platelet-derived growth factor (PDGF-AA) to glycosaminoglycans.

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12 December 2020

The human antimicrobial peptide LL-37 transfers extracellular DNA plasmid to the nuclear compartment of mammalian cells via lipid rafts and proteoglycan-dependent endocytosis.

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12 December 2020

Hagfish intestinal antimicrobial peptides are ancient cathelicidins

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12 December 2020

Mechanisms of action on Escherichia coli of cecropin P1 and PR-39, two antibacterial peptides from pig intestine

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12 December 2020

Sublethal concentrations of pleurocidin-derived antimicrobial peptides inhibit macromolecular synthesis in Escherichia coli

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12 December 2020

Antiviral cyclic D,L-alpha-peptides: targeting a general biochemical pathway in virus infections.

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12 December 2020

The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor.

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12 December 2020

A low-molecular-weight inhibitor against the chemokine receptor CXCR4: a strong anti-HIV peptide T140.

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12 December 2020

Human alpha-defensin 1 (HNP-1) inhibits adenoviral infection in vitro

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12 December 2020

Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity

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12 December 2020

Human beta-defensin-3 promotes wound healing in infected diabetic wounds

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12 December 2020

Innate antimicrobial peptide protects the skin from invasive bacterial infection

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12 December 2020

Wound macrophages express TGF-alpha and other growth factors in vivo: analysis by mRNA phenotyping

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12 December 2020

Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?

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12 December 2020

Mammalian defensins: structures and mechanism of antibiotic activity.

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12 December 2020

Can innate immunity be enhanced to treat microbial infections?

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12 December 2020

10.1007/S00018-011-0710-X

Identifiers

DOI

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24 August 2017

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