Cell-based therapies for Parkinson's disease (Q37886149)

24 August 2017

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title

Cell-based therapies for Parkinson's disease. (English)

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24 August 2017

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2

Roger A Barker

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24 August 2017

Sean C Dyson

1

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24 August 2017

publication date

1 June 2011

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Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders

24 August 2017

published in

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24 August 2017

volume

11

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24 August 2017

issue

6

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24 August 2017

page(s)

831-844

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An essay on the shaking palsy. 1817.

24 August 2017

cites work

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Cognitive dysfunction in Parkinson's disease: the role of frontostriatal circuitry

21 January 2018

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Prevalence and correlates of neuropsychiatric symptoms in Parkinson's disease without dementia

21 January 2018

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The black stuff and Konstantin Nikolaevich Tretiakoff

21 January 2018

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3,4-Dihydroxyphenylalanine and 5-hydroxytryptophan as reserpine antagonists

21 January 2018

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DEMONSTRATION AND MAPPING OUT OF NIGRO-NEOSTRIATAL DOPAMINE NEURONS.

21 January 2018

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FURTHER EVIDENCE FOR THE PRESENCE OF NIGRO-NEOSTRIATAL DOPAMINE NEURONS IN THE RAT.

21 January 2018

1 reference

The nonmotor symptoms of Parkinson's disease--an overview

21 January 2018

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Ontogeny of monoamine neurons in the locus coeruleus, raphe nuclei and substantia nigra of the rat

21 January 2018

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Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up

21 January 2018

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Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease

21 January 2018

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Evidence for long-term survival and function of dopaminergic grafts in progressive Parkinson's disease

21 January 2018

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Factors affecting the clinical outcome after neural transplantation in Parkinson's disease

21 January 2018

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Transplantation of embryonic dopamine neurons for severe Parkinson's disease

21 January 2018

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A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease

21 January 2018

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Dopamine cell implantation in Parkinson's disease: long-term clinical and (18)F-FDOPA PET outcomes

21 January 2018

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Sequential bilateral transplantation in Parkinson's disease: effects of the second graft

21 January 2018

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Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease

21 January 2018

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Reconstructive neurosurgery for Parkinson’s disease: a systematic review and preliminary meta-analysis

21 January 2018

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Deep brain stimulation of the internal segment of the globus pallidus in delayed runaway dyskinesia

21 January 2018

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Deep brain stimulation in Parkinson's disease following fetal nigral transplantation

21 January 2018

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Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration

21 January 2018

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Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants

21 January 2018

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Graft-induced dyskinesias in Parkinson's disease: what is it all about?

21 January 2018

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Dyskinesia after fetal cell transplantation for parkinsonism: a PET study

21 January 2018

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Focal not widespread grafts induce novel dyskinetic behavior in parkinsonian rats

21 January 2018

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Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia

21 January 2018

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Transplantation of adrenal medullary tissue to striatum in parkinsonism. First clinical trials

21 January 2018

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Open microsurgical autograft of adrenal medulla to the right caudate nucleus in two patients with intractable Parkinson's disease.

21 January 2018

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Effect of stereotaxic intrastriatal cografts of autologous adrenal medulla and peripheral nerve in Parkinson's disease: two-year follow-up study

21 January 2018

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Clinical outcome of cotransplantation of peripheral nerve and adrenal medulla in patients with Parkinson's disease. Clínica Puerta de Hierro Neural Transplantation Group

21 January 2018

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Intraputaminal infusion of nerve growth factor to support adrenal medullary autografts in Parkinson's disease. One-year follow-up of first clinical trial

21 January 2018

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Acute oxygen-sensing mechanisms

21 January 2018

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Chemotransduction in the carotid body: K+ current modulated by PO2 in type I chemoreceptor cells

21 January 2018

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Hypoxia induces voltage-dependent Ca2+ entry and quantal dopamine secretion in carotid body glomus cells.

21 January 2018

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Cellular expression of GDNF mRNA suggests multiple functions inside and outside the nervous system

21 January 2018

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Selective glial cell line-derived neurotrophic factor production in adult dopaminergic carotid body cells in situ and after intrastriatal transplantation.

21 January 2018

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GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

21 January 2018

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Glia-like stem cells sustain physiologic neurogenesis in the adult mammalian carotid body.

21 January 2018

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Cellular and functional recovery of Parkinsonian rats after intrastriatal transplantation of carotid body cell aggregates.

21 January 2018

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Recovery of chronic parkinsonian monkeys by autotransplants of carotid body cell aggregates into putamen.

21 January 2018

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Carotid body autotransplantation in Parkinson disease: a clinical and positron emission tomography study.

21 January 2018

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Transplanted xenogeneic neural cells in neurodegenerative disease models exhibit remarkable axonal target specificity and distinct growth patterns of glial and axonal fibres.

21 January 2018

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Increased capacity for axonal outgrowth using xenogenic tissue in vitro and in a rodent model of Parkinson's disease.

21 January 2018

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Human natural antibodies cytotoxic to pig embryonic brain cells recognize novel non-Galalpha1,3Gal-based xenoantigens

21 January 2018

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Alpha Gal is widely expressed in embryonic porcine stem cells and neural tissue.

21 January 2018

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Production of alpha 1,3-galactosyltransferase-deficient pigs

21 January 2018

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Infection of human cells by an endogenous retrovirus of pigs

21 January 2018

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Neural transplantation for the treatment of Parkinson's disease

21 January 2018

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Histological evidence of fetal pig neural cell survival after transplantation into a patient with Parkinson's disease

21 January 2018

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Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system

21 January 2018

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Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease.

21 January 2018

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Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors

21 January 2018

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In vitro generation and transplantation of precursor-derived human dopamine neurons

21 January 2018

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Development of dopaminergic neurons in the mammalian brain

21 January 2018

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How to make a mesodiencephalic dopaminergic neuron

21 January 2018

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Control of neuronal diversity by the floor plate: contact-mediated induction of midbrain dopaminergic neurons.

21 January 2018

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Induction of dopaminergic neuron phenotype in the midbrain by Sonic hedgehog protein

21 January 2018

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FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate

21 January 2018

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An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

21 January 2018

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A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons

21 January 2018

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Dopamine neuron agenesis in Nurr1-deficient mice

21 January 2018

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Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons

21 January 2018

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Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease

21 January 2018

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Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice

21 January 2018

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Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells

21 January 2018

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Enhanced dopaminergic differentiation of human neural stem cells by synergistic effect of Bcl-xL and reduced oxygen tension.

21 January 2018

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Differentiation of mesencephalic progenitor cells into dopaminergic neurons by cytokines

21 January 2018

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Cytokine-induced conversion of mesencephalic-derived progenitor cells into dopamine neurons

21 January 2018

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A clonal line of mesencephalic progenitor cells converted to dopamine neurons by hematopoietic cytokines: a source of cells for transplantation in Parkinson's disease

21 January 2018

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In vitro and in vivo enhanced generation of human A9 dopamine neurons from neural stem cells by Bcl-XL

21 January 2018

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Glial cell line‐derived neurotrophic factor enhances in vitro differentiation of mid‐/hindbrain neural progenitor cells to dopaminergic‐like neurons

21 January 2018

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Differentiation of non-mesencephalic neural stem cells towards dopaminergic neurons

21 January 2018

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Purified mouse dopamine neurons thrive and function after transplantation into brain but require novel glial factors for survival in culture

21 January 2018

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Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease

21 January 2018

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GABAergic immunoreactivity is predominant in neurons derived from expanded human neural precursor cells in vitro.

21 January 2018

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Neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro

21 January 2018

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Functional effect of FGF2- and FGF8-expanded ventral mesencephalic precursor cells in a rat model of Parkinson's disease

21 January 2018

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Establishment in culture of pluripotential cells from mouse embryos

21 January 2018

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Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

21 January 2018

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Isolation of a primate embryonic stem cell line

21 January 2018

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Embryonic stem cell lines derived from human blastocysts

21 January 2018

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Generation of dopaminergic neurons in vitro from human embryonic stem cells treated with neurotrophic factors

21 January 2018

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Derivation of midbrain dopamine neurons from human embryonic stem cells

21 January 2018

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Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.

21 January 2018

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Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells.

21 January 2018

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Efficient derivation of functional dopaminergic neurons from human embryonic stem cells on a large scale

21 January 2018

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Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

21 January 2018

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Human embryonic stem cell-derived dopaminergic neurons reverse functional deficit in parkinsonian rats

21 January 2018

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Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian rats

21 January 2018

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Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins

21 January 2018

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Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis.

21 January 2018

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Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture

21 January 2018

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Adult bone marrow stromal stem cells express germline, ectodermal, endodermal, and mesodermal genes prior to neurogenesis

21 January 2018

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Adult bone marrow stromal cells differentiate into neural cells in vitro

21 January 2018

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Adult bone marrow stromal cells in the embryonic brain: engraftment, migration, differentiation, and long-term survival.

21 January 2018

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Intracerebral transplantation of bone marrow stromal cells in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

21 January 2018

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Rat mesenchymal stem cells increase tyrosine hydroxylase expression and dopamine content in ventral mesencephalic cells in vitro

21 January 2018

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Partial recovery of dopaminergic pathway after graft of adult mesenchymal stem cells in a rat model of Parkinson's disease

21 January 2018

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Shedding light into the role of BDNF in the pharmacotherapy of Parkinson's disease.

21 January 2018

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Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease

21 January 2018

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Intravenous administration of mesenchymal stem cells exerts therapeutic effects on parkinsonian model of rats: focusing on neuroprotective effects of stromal cell-derived factor-1alpha

21 January 2018

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Open-labeled study of unilateral autologous bone-marrow-derived mesenchymal stem cell transplantation in Parkinson's disease

21 January 2018

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

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Multipotent cell lineages in early mouse development depend on SOX2 function

21 January 2018

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Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

21 January 2018

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Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

21 January 2018

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Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4

21 January 2018

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

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Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

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Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

21 January 2018

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Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

21 January 2018

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Virus-free induction of pluripotency and subsequent excision of reprogramming factors

21 January 2018

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Induced pluripotent stem cells generated without viral integration

21 January 2018

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Generation of mouse induced pluripotent stem cells without viral vectors

21 January 2018

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piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

21 January 2018

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Generation of induced pluripotent stem cells using recombinant proteins

21 January 2018

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A nonviral minicircle vector for deriving human iPS cells

21 January 2018

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Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

21 January 2018

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Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions

21 January 2018

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Dopaminergic neurons derived from human induced pluripotent stem cells survive and integrate into 6-OHDA-lesioned rats

21 January 2018

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Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats

21 January 2018

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Disease-specific induced pluripotent stem cells

21 January 2018

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Highly efficient endogenous human gene correction using designed zinc-finger nucleases

21 January 2018

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Direct conversion of fibroblasts to functional neurons by defined factors

21 January 2018

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Dopamine and cholecystokinin immunoreactive neurons in mesencephalic grafts reinnervating the neostriatum: evidence for selective growth regulation

21 January 2018

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The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease

21 January 2018

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Stimulation of subthalamic nucleus alleviates tremor in Parkinson's disease

21 January 2018

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Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease

21 January 2018

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Subthalamic nucleus stimulation in Parkinson disease induces apathy: a PET study

21 January 2018

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Stimulation of subterritories of the subthalamic nucleus reveals its role in the integration of the emotional and motor aspects of behavior.

21 January 2018

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A multicentre study on suicide outcomes following subthalamic stimulation for Parkinson's disease

21 January 2018

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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

21 January 2018

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Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

21 January 2018

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Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years

21 January 2018

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Human neural progenitor cell transplants into the subthalamic nucleus lead to functional recovery in a rat model of Parkinson's disease

21 January 2018

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FETAL DOPAMINE-RICH MESENCEPHALIC GRAFTS IN PARKINSON'S DISEASE

21 January 2018

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Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behaviour

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/ERN.11.33

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24 August 2017

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