TWEAK, a multifunctional cytokine in kidney injury (Q37893443)

24 August 2017

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title

TWEAK, a multifunctional cytokine in kidney injury (English)

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Maria Dolores Sanchez-niño

24 August 2017

Ana Belen Sanz

1

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object named as

Maria D Sanchez-Niño

series ordinal

2

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Alberto Ortiz

object named as

Alberto Ortiz

series ordinal

3

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language of work or name

English

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publication date

22 June 2011

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24 August 2017

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24 August 2017

80

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24 August 2017

7

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24 August 2017

708-718

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https://scigraph.springernature.com/pub.10.1038/ki.2011.180

24 August 2017

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cites work

TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis

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https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Cytokine-receptor pairing: accelerating discovery of cytokine function

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Overview of TNF superfamily: a chest full of potential therapeutic targets

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The TNF and TNF receptor superfamilies: integrating mammalian biology

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7 January 2021

The molecular architecture of the TNF superfamily

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https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Involvement of TWEAK in interferon gamma-stimulated monocyte cytotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Identification of a ligand for the death-domain-containing receptor Apo3

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Involvement of GSK-3beta in TWEAK-mediated NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

IKKbeta/2 induces TWEAK and apoptosis in mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Soluble and transmembrane TNF-like weak inducer of apoptosis differentially activate the classical and noncanonical NF-kappa B pathway

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Studies on the interaction between TWEAK and the death receptor WSL-1/TRAMP (DR3)

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

The apoptotic ligands TRAIL, TWEAK, and Fas ligand mediate monocyte death induced by autologous lupus T cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation

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https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Solution structure of the cysteine-rich domain in Fn14, a member of the tumor necrosis factor receptor superfamily

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

A previously unrecognized protein-protein interaction between TWEAK and CD163: potential biological implications

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

The CD163-expressing macrophages recognize and internalize TWEAK: potential consequences in atherosclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK induces liver progenitor cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK induces angiogenesis and proliferation of endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK attenuates the transition from innate to adaptive immunity

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

The tumor necrosis factor-like weak inducer of apoptosis (TWEAK)-fibroblast growth factor-inducible 14 (Fn14) signaling system regulates glioma cell survival via NFkappaB pathway activation and BCL-XL/BCL-W expression

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

The TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK/Fn14 promotes apoptosis of human endometrial cancer cells via caspase pathway

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK is a positive regulator of cardiomyocyte proliferation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Effects of TWEAK (TNF superfamily member 12) on differentiation, metabolism, and secretory function of human primary preadipocytes and adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Cytokine cooperation in renal tubular cell injury: the role of TWEAK.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Anti-TWEAK monoclonal antibodies reduce immune cell infiltration in the central nervous system and severity of experimental autoimmune encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK/Fn14 pathway: a nonredundant role in intestinal damage in mice through a TWEAK/intestinal epithelial cell axis.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Tumor Necrosis Factor–Like Weak Inducer of Apoptosis (TWEAK) Enhances Vascular and Renal Damage Induced by Hyperlipidemic Diet in ApoE-Knockout Mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK-Fn14 interaction enhances plasminogen activator inhibitor 1 and tissue factor expression in atherosclerotic plaques and in cultured vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

The interaction between tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 promotes the recruitment of neutrophils into the ischemic brain

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Tumor necrosis-like weak inducer of apoptosis as a proinflammatory cytokine in human adipocyte cells: up-regulation in severe obesity is mediated by inflammation but not hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14 during cardiac remodelling in rats.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Direct targeting of fibroblast growth factor-inducible 14 protein protects against renal ischemia reperfusion injury

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Tweak induces proliferation in renal tubular epithelium: a role in uninephrectomy induced renal hyperplasia

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK can induce pro-inflammatory cytokines and matrix metalloproteinase-9 in macrophages

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK stimulation of kidney resident cells in the pathogenesis of graft versus host induced lupus nephritis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TNF-like weak inducer of apoptosis (TWEAK) induces inflammatory and proliferative effects in human kidney cells.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Fn14 is upregulated in cytokine-stimulated vascular smooth muscle cells and is expressed in human carotid atherosclerotic plaques: modulation by atorvastatin

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK is an endothelial cell growth and chemotactic factor that also potentiates FGF-2 and VEGF-A mitogenic activity

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

FGF-inducible 14-kDa protein (Fn14) is regulated via the RhoA/ROCK kinase pathway in cardiomyocytes and mediates nuclear factor-kappaB activation by TWEAK.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Proinflammatory effects of TWEAK/Fn14 interactions in glomerular mesangial cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Tubular epithelial cells: A critical cell type in the regulation of renal inflammatory processes

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Mechanism of steroid action in renal epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

NF-kappaB in renal inflammation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

The cytokine TWEAK modulates renal tubulointerstitial inflammation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK activates the non-canonical NFkappaB pathway in murine renal tubular cells: modulation of CCL21

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Roles of SLC/CCL21 and CCR7 in human kidney for mesangial proliferation, migration, apoptosis, and tissue homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Tumor necrosis factor-related weak inducer of apoptosis augments matrix metalloproteinase 9 (MMP-9) production in skeletal muscle through the activation of nuclear factor-kappaB-inducing kinase and p38 mitogen-activated protein kinase: a potential r

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Expression of apoptosis regulatory proteins in tubular epithelium stressed in culture or following acute renal failure

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

The death ligand TRAIL in diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Fas transduces activation signals in normal human T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis-Induced Neurodegeneration

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Therapeutic targeting of TWEAK/Fnl4 in cancer: exploiting the intrinsic tumor cell killing capacity of the pathway

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Acute renal injury in the interferon-gamma gene knockout mouse: effect on cytokine gene expression

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Caspase inhibition causes hyperacute tumor necrosis factor-induced shock via oxidative stress and phospholipase A2.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Tumor necrosis factor primes hepatocytes for DNA replication in the rat

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Analysis of liver regeneration in mice lacking type 1 or type 2 tumor necrosis factor receptor: requirement for type 1 but not type 2 receptor

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK is expressed by glial cells, induces astrocyte proliferation and increases EAE severity

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Pro-inflammatory cytokines TNF-related weak inducer of apoptosis (TWEAK) and TNFalpha induce the mitogen-activated protein kinase (MAPK)-dependent expression of sclerostin in human osteoblasts

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK regulates proliferation and differentiation of adult neural progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Expression of Smac/Diablo in tubular epithelial cells and during acute renal failure.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Induction of the cytokine TWEAK and its receptor Fn14 in ischemic stroke

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK and Fn14. New players in the pathogenesis of atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Down-regulated expression of TWEAK mRNA in acute and chronic inflammatory pathologies

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Urinary TWEAK and the activity of lupus nephritis.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Elevation of human tumor necrosis factor-like weak inducer of apoptosis in peripheral blood mononuclear cells is correlated with disease activity and lupus nephritis in patients with systemic lupus erythematosus.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

TWEAK/Fn14 interactions are instrumental in the pathogenesis of nephritis in the chronic graft-versus-host model of systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

The role of aldosterone blockade in murine lupus nephritis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Glomerular haematuria, renal interstitial haemorrhage and acute kidney injury

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Folate nephropathy occurring during cytotoxic chemotherapy with high-dose folinic acid and 5-fluorouracil

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Role of Parathyroid Hormone-Related Protein in Tubulointerstitial Apoptosis and Fibrosis after Folic Acid-Induced Nephrotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Production of inflammatory mediators by renal epithelial cells is insensitive to glucocorticoids

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

No aggravation of renal injury in apolipoprotein E knockout mice (ApoE(-/-)) after subtotal nephrectomy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Mesangial expansion associated with glomerular endothelial cell activation and macrophage recruitment is developing in hyperlipidaemic apoE null mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Renal injury in apolipoprotein E-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Compensatory kidney growth in estrogen receptor-alpha null mice.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Compensatory renal growth in uninephrectomized adult mice is growth hormone dependent.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Fibroblast growth factor-inducible-14 is induced in axotomized neurons and promotes neurite outgrowth

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Involvement of TNF-like weak inducer of apoptosis in the pathogenesis of collagen-induced arthritis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Peripheral Artery Disease Is Associated With a High CD163/TWEAK Plasma Ratio

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Circulating sTWEAK improves the prediction of coronary artery disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Decreased soluble TWEAK levels predict an adverse prognosis in patients with chronic stable heart failure.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Differences in the predictive value of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in advanced ischemic and non-ischemic heart failure

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Soluble TWEAK plasma levels predict expansion of human abdominal aortic aneurysms

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Additive effects of soluble TWEAK and inflammation on mortality in hemodialysis patients

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Soluble TWEAK plasma levels as a novel biomarker of endothelial function in patients with chronic kidney disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Serum levels of the atherosclerosis biomarker sTWEAK are decreased in type 2 diabetes and end-stage renal disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Combined therapy with renin-angiotensin system and calcium channel blockers in type 2 diabetic hypertensive patients with proteinuria: effects on soluble TWEAK, PTX3, and flow-mediated dilation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Soluble TWEAK is markedly elevated in hemophagocytic lymphohistiocytosis.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Circulating levels of TWEAK correlate with bone erosion in multiple myeloma patients

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Soluble TWEAK is markedly upregulated in patients with ST-elevation myocardial infarction and related to an adverse short-term outcome.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Diagnosis and treatment of kidney disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Urinary TWEAK as a biomarker of lupus nephritis: a multicenter cohort study.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2011.180

7 January 2021

Identifiers

DOI

10.1038/KI.2011.180

1 reference

24 August 2017

1 reference

PubMed ID

21697814