Diabetes mellitus and periodontitis: a tale of two common interrelated diseases (Q37895120)

24 August 2017

1 reference

title

Diabetes mellitus and periodontitis: a tale of two common interrelated diseases (English)

1 reference

24 August 2017

0 references

Evanthia Lalla

1

1 reference

PubMed ID

21709707

24 August 2017

Panos N Papapanou

series ordinal

2

1 reference

24 August 2017

28 June 2011

1 reference

Nature Reviews Endocrinology

24 August 2017

1 reference

24 August 2017

7

1 reference

24 August 2017

12

1 reference

24 August 2017

738-748

1 reference

https://scigraph.springernature.com/pub.10.1038/nrendo.2011.106

24 August 2017

0 references

cites work

Periodontal diseases.

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Risk of aggressive periodontitis in adolescent carriers of the JP2 clone of Aggregatibacter (Actinobacillus) actinomycetemcomitans in Morocco: a prospective longitudinal cohort study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Periodontitis: a polymicrobial disruption of host homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

"Gum bug, leave my heart alone!"--epidemiologic and mechanistic evidence linking periodontal infections and atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Epidemiologic patterns of chronic and aggressive periodontitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Analytical epidemiology of periodontitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Diabetes mellitus and periodontal diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Periodontal disease: associations with diabetes, glycemic control and complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Periodontal changes in children and adolescents with diabetes: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Diabetes mellitus promotes periodontal destruction in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

The relationship between clinical periodontal status and insulin-dependent diabetes mellitus. Results after 5 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Periodontal status and subgingival microbiota of insulin-dependent juvenile diabetics: a 3-year longitudinal study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Periodontal disease progression and glycaemic control among Gullah African Americans with type-2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

The effect of periodontal therapy in diabetics. Results after 5 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Relationship between obesity and physical fitness and periodontitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Association between chronic periodontal disease and obesity: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Association between periodontal infection and obesity: results of the Health 2000 Survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Severe periodontitis is associated with systemic inflammation and a dysmetabolic status: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Metabolic syndrome, periodontal infection, and dental caries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Relationship between metabolic syndrome and periodontal disease in Japanese adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Medical status and complications in relation to periodontal disease experience in insulin-dependent diabetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Periodontal disease and mortality in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Severe periodontitis and risk for poor glycemic control in patients with non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Periodontal disease and incident type 2 diabetes: results from the First National Health and Nutrition Examination Survey and its epidemiologic follow-up study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Periodontal disease and incident diabetes: a seven-year study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

The role of inflammatory cytokines in diabetes and its complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Inflammation and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Inflammatory markers and risk of developing type 2 diabetes in women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Effect of periodontal treatment on glycemic control of diabetic patients: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

The effect of periodontal treatment on glycemic control in patients with type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

The effect of periodontal therapy on uncontrolled type 2 diabetes mellitus in older subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

The effect of improved periodontal health on metabolic control in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Does periodontal care improve glycemic control? The Department of Veterans Affairs Dental Diabetes Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Increasing body mass index z-score is continuously associated with complications of overweight in children, even in the healthy weight range

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Clinical and radiological improvement of periodontal disease in patients with type 2 diabetes mellitus treated with alendronate: a randomized, placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Comparative evaluation of adjunctive oral irrigation in diabetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Effect of non-surgical periodontal therapy on glycemic control in patients with type 2 diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Efficacy of periodontal treatment on glycaemic control in diabetic patients: A meta-analysis of interventional studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Association of hemoglobin A1c with cardiovascular disease and mortality in adults: the European prospective investigation into cancer in Norfolk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Periodontal infection profiles in type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Enhanced superoxide release and elevated protein kinase C activity in neutrophils from diabetic patients: association with periodontitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Chronic hyperglycemia predisposes to exaggerated inflammatory response and leukocyte dysfunction in Akita mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Type 1 diabetes predisposes to enhanced gingival leukocyte margination and macromolecule extravasation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Experimental gingivitis in type 1 diabetics: a controlled clinical and microbiological study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Diabetes prolongs the inflammatory response to a bacterial stimulus through cytokine dysregulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Inflammation is more persistent in type 1 diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

The effect of Porphyromonas gingivalis infection on cytokine levels in type 2 diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

The effect of systemic anti-tumor necrosis factor-alpha treatment on Porphyromonas gingivalis infection in type 2 diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Morphometric analysis of cellular and vascular changes in gingival connective tissue in long-term insulin-dependent diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Alloxan-induced diabetes triggers the development of periodontal disease in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

G(-) anaerobes-reactive CD4+ T-cells trigger RANKL-mediated enhanced alveolar bone loss in diabetic NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Diabetes enhances periodontal bone loss through enhanced resorption and diminished bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Diabetes alters the response to bacteria by enhancing fibroblast apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Tumor necrosis factor-alpha mediates diabetes-enhanced apoptosis of matrix-producing cells and impairs diabetic healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Altered fibroblast proliferation and apoptosis in diabetic gingival wounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Impaired wound healing in mouse models of diabetes is mediated by TNF-alpha dysregulation and associated with enhanced activation of forkhead box O1 (FOXO1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Receptor for AGE (RAGE) and its ligands-cast into leading roles in diabetes and the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Advanced glycation endproducts (AGEs) induce oxidant stress in the gingiva: a potential mechanism underlying accelerated periodontal disease associated with diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Advanced glycation end products inhibit the expression of collagens type I and III by human gingival fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Blockade of RAGE suppresses periodontitis-associated bone loss in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Direct inhibitory and indirect stimulatory effects of RAGE ligand S100 on sRANKL-induced osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Blockade of receptor for advanced glycation end-products restores effective wound healing in diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

A role for advanced glycation end products in diminished bone healing in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Systemic markers of inflammation in periodontitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Periodontitis is associated with aggravation of prediabetes in Zucker fatty rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Diverse effect of inflammatory markers on insulin resistance and insulin-resistance syndrome in the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Serum levels of soluble tumor necrosis factor-alpha receptor 2 are linked to insulin resistance and glucose intolerance in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

A systematic review and meta-analyses on C-reactive protein in relation to periodontitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

The effect of antimicrobial periodontal treatment on circulating tumor necrosis factor-alpha and glycated hemoglobin level in patients with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Effects of periodontal therapy on serum C-reactive protein, sE-selectin, and tumor necrosis factor-alpha secretion by peripheral blood-derived macrophages in diabetes. A pilot study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Effect of antimicrobial periodontal treatment and maintenance on serum adiponectin in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Effect of periodontal treatment on metabolic control, systemic inflammation and cytokines in patients with type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Changes of adiponectin and inflammatory cytokines after periodontal intervention in type 2 diabetes patients with periodontitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

The potential role of dentists in identifying patients' risk of experiencing coronary heart disease events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Diabetes in the dental office: using NHANES III to estimate the probability of undiagnosed disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Development of a clinical guideline to predict undiagnosed diabetes in dental patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Identification of unrecognized diabetes and pre-diabetes in a dental setting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Periodontitis and obesity: a study of the Fourth Korean National Health and Nutrition Examination Survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Non-insulin dependent diabetes mellitus and alveolar bone loss progression over 2 years

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Periodontal disease related to diabetic status. A pilot study of the response to periodontal therapy in type 1 diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Healing response to non-surgical periodontal therapy in patients with diabetes mellitus: clinical, microbiological, and immunologic results

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Clinical and metabolic changes after conventional treatment of type 2 diabetic patients with chronic periodontitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Association of the metabolic syndrome with severe periodontitis in a large U.S. population-based survey

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

A cohort study on the association between periodontal disease and the development of metabolic syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Effect of periodontitis on overt nephropathy and end-stage renal disease in type 2 diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Treatment of periodontal disease for glycaemic control in people with diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Multi-center intervention study on glycohemoglobin (HbA1c) and serum, high-sensitivity CRP (hs-CRP) after local anti-infectious periodontal treatment in type 2 diabetic patients with periodontal disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Treatment of periodontal disease in diabetics reduces glycated hemoglobin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

A randomized, controlled trial on the effect of non-surgical periodontal therapy in patients with type 2 diabetes. Part I: effect on periodontal status and glycaemic control

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Microbiological and immunological studies of adult periodontitis in patients with noninsulin-dependent diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Some suspected periodontopathogens and serum antibody response in adult long-duration insulin-dependent diabetics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Comparison of neutrophil chemotactic response in diabetic patients with mild and severe periodontal disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Monocytic TNF alpha secretion patterns in IDDM patients with periodontal diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

PGE2, IL-1 beta, and TNF-alpha responses in diabetics as modifiers of periodontal disease expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Influence of diabetes on the exacerbation of an inflammatory response in cardiovascular tissue

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Expression of matrix metalloproteinases (MMP-8 and -9) in chronic periodontitis patients with and without diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Markers of bone destruction and formation and periodontitis in type 1 diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Receptor activator of nuclear factor-kappa B ligand/osteoprotegerin ratio in sites of chronic periodontitis of subjects with poorly and well-controlled type 2 diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Diabetes modulates gene expression in the gingival tissues of patients with chronic periodontitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Diabetes causes decreased osteoclastogenesis, reduced bone formation, and enhanced apoptosis of osteoblastic cells in bacteria stimulated bone loss

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Diabetes enhances mRNA levels of proapoptotic genes and caspase activity, which contribute to impaired healing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Relationship of serum advanced glycation end products with deterioration of periodontitis in type 2 diabetes patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Expression of the receptor of advanced glycation end products in gingival tissues of type 2 diabetes patients with chronic periodontal disease: a study utilizing immunohistochemistry and RT-PCR

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Advanced glycation of type I collagen and fibronectin modifies periodontal cell behavior

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

A murine model of accelerated periodontal disease in diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Plasma levels of tumour necrosis factor-alpha in patients with chronic periodontitis and type 2 diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Effects of periodontal therapy on glycemic control and inflammatory markers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.106

Periodontal disease progression in type II non-insulin-dependent diabetes mellitus patients (NIDDM). Part I--Probing pocket depth and clinical attachment.

31 March 2020

1 reference

12 December 2020

The dental office visit as a potential opportunity for diabetes screening: an analysis using NHANES 2003-2004 data.

1 reference

12 December 2020

The relationship between diabetes mellitus and destructive periodontal disease: a meta-analysis.

1 reference

12 December 2020

Periodontal disease progression in type II non-insulin-dependent diabetes mellitus patients (NIDDM). Part II--Microbiological analysis using the BANA test.

1 reference

12 December 2020

Local and systemic factors in periodontal disease increase matrix-degrading enzyme activities in rat gingiva: effect of micocycline therapy

1 reference

12 December 2020

Effect of non-surgical periodontal therapy on patients with type 2 diabetes mellitus.

1 reference

12 December 2020

Actinobacillus actinomycetemcomitans in Brazilian insulin-dependent individuals with diabetes mellitus

1 reference

12 December 2020

Streptozotocin-induced Diabetes and the Rat Periodontium: Decreased Relative Collagen Production

1 reference

12 December 2020

In vivo crevicular leukocyte response to a chemotactic challenge: inhibition by experimental diabetes.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRENDO.2011.106

1 reference

24 August 2017

1 reference

PubMed ID

21709707