A BACwards glance at neurodegeneration: molecular insights into disease from LRRK2, SNCA and MAPT BAC-transgenic mice. (Q37905119)

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8 February 2020

review article

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title

A BACwards glance at neurodegeneration: molecular insights into disease from LRRK2, SNCA and MAPT BAC-transgenic mice (English)

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8 February 2020

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2

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8 February 2020

author name string

Sara J Johnson

series ordinal

1

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publication date

1 August 2011

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Biochemical Society Transactions

8 February 2020

published in

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volume

39

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issue

4

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8 February 2020

page(s)

862-867

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Genetic transformation of mouse embryos by microinjection of purified DNA

8 February 2020

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Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S

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Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease

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Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes.

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Expansion of the Parkinson disease-associated SNCA-Rep1 allele upregulates human alpha-synuclein in transgenic mouse brain.

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Genome-wide association study reveals genetic risk underlying Parkinson's disease

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Mechanisms of tau-induced neurodegeneration

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Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

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Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms

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21 January 2018

Identifiers

DOI

10.1042/BST0390862

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21787314%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

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