Animal tumor models for PET in drug development (Q37924161)

25 August 2017

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title

Animal tumor models for PET in drug development (English)

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25 August 2017

Jun Toyohara

1

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25 August 2017

Kiichi Ishiwata

series ordinal

2

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25 August 2017

publication date

31 August 2011

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Annals of Nuclear Medicine

25 August 2017

published in

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25 August 2017

volume

25

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25 August 2017

issue

10

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25 August 2017

page(s)

717-731

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MicroPET imaging of brain tumor angiogenesis with 18F-labeled PEGylated RGD peptide

25 August 2017

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21 January 2018

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21 January 2018

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Noninvasive visualization of the activated alphavbeta3 integrin in cancer patients by positron emission tomography and [18F]Galacto-RGD

21 January 2018

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Distribution of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) uracil in mice bearing colorectal cancer xenografts: rationale for therapeutic use and as a positron emission tomography probe for thymidylate synthase.

21 January 2018

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In vitro and in vivo investigation of matrix metalloproteinase expression in metastatic tumor models

21 January 2018

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A new PET tracer specific for vascular endothelial growth factor receptor 2.

21 January 2018

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In vivo evaluation and small-animal PET/CT of a prostate cancer mouse model using 64Cu bombesin analogs: side-by-side comparison of the CB-TE2A and DOTA chelation systems

21 January 2018

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Molecular imaging of EGFR kinase activity in tumors with 124I-labeled small molecular tracer and positron emission tomography.

21 January 2018

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Quantitative immuno-positron emission tomography imaging of HER2-positive tumor xenografts with an iodine-124 labeled anti-HER2 diabody

21 January 2018

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Breast cancer models to study the expression of estrogen receptors with small animal PET imaging.

21 January 2018

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A small animal positron emission tomography study of the effect of chemotherapy and hormonal therapy on the uptake of 2-deoxy-2-[F-18]fluoro-D-glucose in murine models of breast cancer.

21 January 2018

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Development of a bicistronic vector for multimodality imaging of estrogen receptor activity in a breast cancer model: preliminary application

21 January 2018

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Imaging proliferation to monitor early response of lymphoma to cytotoxic treatment

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Early detection of chemoradioresponse in esophageal carcinoma by 3'-deoxy-3'-3H-fluorothymidine using preclinical tumor models

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Early detection of tumor response to chemotherapy by 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography: the effect of cisplatin on a fibrosarcoma tumor model in vivo

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Preclinical efficacy of the c-Met inhibitor CE-355621 in a U87 MG mouse xenograft model evaluated by 18F-FDG small-animal PET.

21 January 2018

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FDG-PET imaging for the evaluation of antiglioma agents in a rat model

21 January 2018

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The novel DNA methylation inhibitor zebularine is effective against the development of murine T-cell lymphoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

FDG-PET for pharmacodynamic assessment of the fatty acid synthase inhibitor C75 in an experimental model of lung cancer.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Antitumor and antivascular effects of AVE8062 in ovarian carcinoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

3'-deoxy-3'-[18F]fluorothymidine positron emission tomography is a sensitive method for imaging the response of BRAF-dependent tumors to MEK inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Clinical development of histone deacetylase inhibitors as anticancer agents

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Multi-tracer small animal PET imaging of the tumour response to the novel pan-Erb-B inhibitor CI-1033.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Non-invasive PET imaging of EGFR degradation induced by a heat shock protein 90 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Tumor viability evaluation by positron emission tomography with [18F]FDG in the liver metastasis rat model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Evaluation of tumor growth in vivo in a rat model of liver metastasis, using a newly devised index obtained by positron emission tomography with [18F] FDG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Anesthesia condition for (18)F-FDG imaging of lung metastasis tumors using small animal PET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Successful high-resolution animal positron emission tomography of human Ewing tumours and their metastases in a murine xenograft model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Characterization of osteolytic, osteoblastic, and mixed lesions in a prostate cancer mouse model using 18F-FDG and 18F-fluoride PET/CT

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Multimodality imaging of IL-18--binding protein-Fc therapy of experimental lung metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

FDG-PET in the detection of early pancreatic cancer in a BOP hamster model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

The use of dynamic positron emission tomography imaging for evaluating the carcinogenic progression of intestinal metaplasia to esophageal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Animal PET for thioacetamide-induced rat cholangiocarcinoma: a novel and reliable platform

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Dynamic small-animal PET imaging of tumor proliferation with 3'-deoxy-3'-18F-fluorothymidine in a genetically engineered mouse model of high-grade gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Lymph node metastasis: ultrasmall superparamagnetic iron oxide-enhanced MR imaging versus PET/CT in a rabbit model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

FDG-PET for evaluating the antitumor effect of intraarterial 3-bromopyruvate administration in a rabbit VX2 liver tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Changes in 18F-FDG uptake within minutes after chemotherapy in a rabbit VX2 tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Correlation between hepatic tumor blood flow and glucose utilization in a rabbit liver tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Longitudinal microPET imaging of brain tumor growth with F-18-labeled RGD peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Improved synthesis of no-carrier-added p-[124I]iodo-L-phenylalanine and p-[131I]iodo-L-phenylalanine for nuclear medicine applications in malignant gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

The synthesis of 18F-FDS and its potential application in molecular imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Setup and characterization of a human head and neck squamous cell carcinoma xenograft model in nude rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

L-type amino acid transporters LAT1 and LAT4 in cancer: uptake of 3-O-methyl-6-18F-fluoro-L-dopa in human adenocarcinoma and squamous cell carcinoma in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Monitoring response to radiotherapy in human squamous cell cancer bearing nude mice: comparison of 2'-deoxy-2'-[18F]fluoro-D-glucose (FDG) and 3'-[18F]fluoro-3'-deoxythymidine (FLT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluoresce

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Effect of increase of radiation dose on local control relates to pre-treatment FDG uptake in FaDu tumours in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Evaluation of biodistribution and anti-tumor effect of a dimeric RGD peptide-paclitaxel conjugate in mice with breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Synthesis, biodistribution and micro-PET imaging of radiolabeled antimitotic agent T138067 analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Tumor volume in subcutaneous mouse xenografts measured by microCT is more accurate and reproducible than determined by 18F-FDG-microPET or external caliper

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

FDG small animal PET permits early detection of malignant cells in a xenograft murine model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Gene expression patterns and tumor uptake of 18F-FDG, 18F-FLT, and 18F-FEC in PET/MRI of an orthotopic mouse xenotransplantation model of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

The effects of anesthetic agent and carrier gas on blood glucose and tissue uptake in mice undergoing dynamic FDG-PET imaging: sevoflurane and isoflurane compared in air and in oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Biodistribution and imaging of FDG in rats with LS174T carcinoma xenografts and focal Escherichia coli infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Noninvasive imaging of cell proliferation following mitogenic extracellular kinase inhibition by PD0325901.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Synthesis and evaluation in vitro and in vivo of a 11C-labeled cyclooxygenase-2 (COX-2) inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

PET radioimmunoscintigraphy of renal cell cancer using 89Zr-labeled cG250 monoclonal antibody in nude rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Small-animal PET imaging of human epidermal growth factor receptor type 2 expression with site-specific 18F-labeled protein scaffold molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

[11C] acetoacetate utilization by breast and prostate tumors: a PET and biodistribution study in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Comparative in vitro and in vivo evaluation of two 64Cu-labeled bombesin analogs in a mouse model of human prostate adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

A preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Non-invasive evaluation of tumour hypoxia in the Shionogi tumour model for prostate cancer with 18F-EF5 and positron emission tomography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

FLT-PET imaging of radiation responses in murine tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Kinetic modeling of 3'-deoxy-3'-18F-fluorothymidine for quantitative cell proliferation imaging in subcutaneous tumor models in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Monitoring the efficacy of adoptively transferred prostate cancer-targeted human T lymphocytes with PET and bioluminescence imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Imaging of melanoma using 64Cu- and 86Y-DOTA-ReCCMSH(Arg11), a cyclized peptide analogue of alpha-MSH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

[F-18]-Fluoro-2-deoxy-D: -glucose positron emission tomography as a tool for early detection of immunotherapy response in a murine B cell lymphoma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Determination of tumour hypoxia with the PET tracer [18F]EF3: improvement of the tumour-to-background ratio in a mouse tumour model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

MicroPET-based pharmacokinetic analysis of the radiolabeled boron compound [18F]FBPA-F in rats with F98 glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Evaluation of F-18-labeled amino acid derivatives and [18F]FDG as PET probes in a brain tumor-bearing animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Monitoring HSVtk suicide gene therapy: the role of [(18)F]FHPG membrane transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Autoradiographic and small-animal PET comparisons between (18)F-FMISO, (18)F-FDG, (18)F-FLT and the hypoxic selective (64)Cu-ATSM in a rodent model of cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Normal brain cells contribute to the bystander effect in suicide gene therapy of malignant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Comparison of 18F-fluoromethylcholine and 2-deoxy-D-glucose in the distribution of tumor and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Extensive FDG uptake and its modification with corticosteroid in a granuloma rat model: an experimental study for differentiating granuloma from tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Evaluation of hypoxia in an experimental rat tumour model by [(18)F]fluoromisonidazole PET and immunohistochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

In vitro and in vivo evaluations of a hydrophilic 64Cu-bis(thiosemicarbazonato)-glucose conjugate for hypoxia imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Radiolabeled phenethylguanidines: novel imaging agents for cardiac sympathetic neurons and adrenergic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

Comparison of dynamic FDG-microPET study in a rabbit turpentine-induced inflammatory model and in a rabbit VX2 tumor model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12149-011-0531-X

10.1007/S12149-011-0531-X

21 January 2018

Identifiers

DOI

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release_aktmcnt54vamzkuaq24374odbm

25 August 2017

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mapped directly with Wikidata item

24 November 2022

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