Rational engineering of Escherichia coli strains for plasmid biopharmaceutical manufacturing (Q37931183)

25 August 2017

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title

Rational engineering of Escherichia coli strains for plasmid biopharmaceutical manufacturing (English)

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25 August 2017

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Gabriel A Monteiro

4

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author name string

Geisa A L Gonçalves

1

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25 August 2017

Diana M Bower

2

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25 August 2017

Duarte M F Prazeres

3

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25 August 2017

Kristala L J Prather

5

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25 August 2017

publication date

13 September 2011

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25 August 2017

published in

Biotechnology Journal

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25 August 2017

volume

7

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25 August 2017

issue

2

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25 August 2017

page(s)

251-261

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DNA vaccines: an historical perspective and view to the future

25 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

DNA vaccines: ready for prime time?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

DNA and RNA-based vaccines: principles, progress and prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Purification of plasmids for gene therapy and DNA vaccination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Host strain influences on supercoiled plasmid DNA production in Escherichia coli: Implications for efficient design of large-scale processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Ensuring safety of DNA vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Studies of host-plasmid interactions in recombinant microorganisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Plasmid effects on Escherichia coli metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Generic plasmid DNA production platform incorporating low metabolic burden seed-stock and fed-batch fermentation processes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Effects of the presence of ColE1 plasmid DNA in Escherichia coli on the host cell metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Plasmid-encoded protein: the principal factor in the "metabolic burden" associated with recombinant bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

DNA plasmid production in different host strains of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Factors affecting plasmid production in Escherichia coli from a resource allocation standpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Growth-rate recovery of Escherichia coli cultures carrying a multicopy plasmid, by engineering of the pentose-phosphate pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Metabolic flux analysis of pykF gene knockout Escherichia coli based on 13C-labeling experiments together with measurements of enzyme activities and intracellular metabolite concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Cloning of the two pyruvate kinase isoenzyme structural genes from Escherichia coli: the relative roles of these enzymes in pyruvate biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Pyruvate kinase-deficient Escherichia coli exhibits increased plasmid copy number and cyclic AMP levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Plasmid DNA fermentation strain and process‐specific effects on vector yield, quality, and transgene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Inactivating FruR global regulator in plasmid-bearing Escherichia coli alters metabolic gene expression and improves growth rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Enhancement of plasmid DNA yields during fed-batch culture of a fruR-knockout Escherichia coli strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Modified Escherichia coli B (BL21), a superior producer of plasmid DNA compared with Escherichia coli K (DH5alpha).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

E. coli host strains significantly affect the quality of small scale plasmid DNA preparations used for sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Epigenetic regulation of the bacterial cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

EcoCyc: a comprehensive database of Escherichia coli biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

ppGpp: a global regulator in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Plasmid DNA manufacturing technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

DNA vaccine manufacture: scale and quality

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Manufacturing and quality control of plasmid-based gene expression systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Engineering of bacterial strains and vectors for the production of plasmid DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Plasmid DNA vaccine vector design: impact on efficacy, safety and upstream production

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Escherichia coli K-12: a cooperatively developed annotation snapshot--2005

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Glucose metabolism at high density growth of E. coli B and E. coli K: differences in metabolic pathways are responsible for efficient glucose utilization in E. coli B as determined by microarrays and Northern blot analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Escherichia coli strains that allow antibiotic-free plasmid selection and maintenance by repressor titration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

pCOR: a new design of plasmid vectors for nonviral gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Improved antibiotic-free DNA vaccine vectors utilizing a novel RNA based plasmid selection system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Critical design criteria for minimal antibiotic‐free plasmid vectors necessary to combine robust RNA Pol II and Pol III‐mediated eukaryotic expression with high bacterial production yields

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Biosafety of DNA vaccines: New generation of DNA vectors and current knowledge on the fate of plasmids after injection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Progress and prospects: the design and production of plasmid vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

A robust system for production of minicircle DNA vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Structural instability of plasmid biopharmaceuticals: challenges and implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Identification and characterization of IS1 transposition in plasmid amplification mutants of E. coli clones producing DNA vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Deletion formation mutations in plasmid expression vectors are unfavored by runaway amplification conditions and differentially selected under kanamycin stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Emergent properties of reduced-genome Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Gene expression profiling by DNA microarrays and metabolic fluxes in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Effects of fermentation strategy on the characteristics of plasmid DNA production

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

High copy number of the pUC plasmid results from a Rom/Rop‐suppressible point mutation in RNA II

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Inducible Escherichia coli fermentation for increased plasmid DNA production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Effect of temperature up-shift on fermentation and metabolic characteristics in view of gene expressions in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Proteome analysis of the Escherichia coli heat shock response under steady-state conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

The effect of heating rate on Escherichia coli metabolism, physiological stress, transcriptional response, and production of temperature-induced recombinant protein: a scale-down study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Comparative studies on in vitro expression and in vivo immunogenicity of supercoiled and open circular forms of plasmid DNA vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Separation of supercoiled from open circular forms of plasmid DNA, and biological activity detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Plasmid DNA supercoiling and gyrase activity in Escherichia coli wild-type and rpoS stationary-phase cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

pFARs, plasmids free of antibiotic resistance markers, display high-level transgene expression in muscle, skin and tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

The complete genome sequence of Escherichia coli DH10B: insights into the biology of a laboratory workhorse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

Marker-free plasmids for gene therapeutic applications—Lack of antibiotic resistance gene substantially improves the manufacturing process

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201100062

21 January 2018

Identifiers

DOI

10.1002/BIOT.201100062

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25 August 2017

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