PI3K-Akt-mTOR and MAPK signaling pathways in polycystic ovarian syndrome, uterine leiomyomas and endometriosis: an update (Q37931976)

25 August 2017

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title

PI3K-Akt-mTOR and MAPK signaling pathways in polycystic ovarian syndrome, uterine leiomyomas and endometriosis: an update (English)

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25 August 2017

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3

Vinita Das

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25 August 2017

4

Anjoo Agarwal

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25 August 2017

1

Annu Makker

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25 August 2017

2

Madhu Mati Goel

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25 August 2017

publication date

15 September 2011

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Gynecological Endocrinology

25 August 2017

published in

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25 August 2017

volume

28

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25 August 2017

issue

3

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25 August 2017

page(s)

175-181

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The phosphoinositide 3-kinase pathway

25 August 2017

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Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis

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The RAF proteins take centre stage

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Growth factors and mitogen-activated protein kinases

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21 January 2018

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The androgen receptor CAG repeat modifies the impact of testosterone on insulin resistance in women with polycystic ovary syndrome.

21 January 2018

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Effects of metformin and ethinyl estradiol-cyproterone acetate on clinical, endocrine and metabolic factors in women with polycystic ovary syndrome

21 January 2018

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Phosphatidylinositol 3-kinase p85alpha regulatory subunit gene Met326Ile polymorphism in women with polycystic ovary syndrome

21 January 2018

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Effect of testosterone on insulin stimulated IRS1 Ser phosphorylation in primary rat myotubes--a potential model for PCOS-related insulin resistance

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Luteinizing hormone-induced Akt phosphorylation and androgen production are modulated by MAP Kinase in bovine theca cells

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Alterations in mitogen-activated protein kinase kinase and extracellular regulated kinase signaling in theca cells contribute to excessive androgen production in polycystic ovary syndrome

21 January 2018

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Selective alterations in insulin receptor substrates-1, -2 and -4 in theca but not granulosa cells from polycystic ovaries

21 January 2018

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Metformin alters insulin signaling and viability of human granulosa cells.

21 January 2018

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Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene

21 January 2018

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Metformin inhibits aromatase via an extracellular signal-regulated kinase-mediated pathway

21 January 2018

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Insulin attenuates the insulin-like growth factor-I (IGF-I)-Akt pathway, not IGF-I-extracellularly regulated kinase pathway, in luteinized granulosa cells with an increase in PTEN.

21 January 2018

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21 January 2018

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21 January 2018

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Involvement of Akt, Ras and cell cycle regulators in the potential development of endometrial hyperplasia in women with polycystic ovarian syndrome.

21 January 2018

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21 January 2018

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Pioglitazone enhances mitochondrial biogenesis and ribosomal protein biosynthesis in skeletal muscle in polycystic ovary syndrome

21 January 2018

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Enhanced mitogenic signaling in skeletal muscle of women with polycystic ovary syndrome.

21 January 2018

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Insulin resistance in polycystic ovary syndrome is associated with defective regulation of ERK1/2 by insulin in skeletal muscle in vivo.

21 January 2018

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Amelioration of insulin resistance in women with PCOS via reduced insulin receptor substrate-1 Ser312 phosphorylation following laparoscopic ovarian electrocautery.

21 January 2018

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Human uterine smooth muscle and leiomyoma cells differ in their rapid 17beta-estradiol signaling: implications for proliferation

21 January 2018

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Estrogen receptor alpha (ERalpha) phospho-serine-118 is highly expressed in human uterine leiomyomas compared to matched myometrium

21 January 2018

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A low concentration of genistein induces estrogen receptor-alpha and insulin-like growth factor-I receptor interactions and proliferation in uterine leiomyoma cells

21 January 2018

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Differential expression of receptor tyrosine kinases (RTKs) and IGF-I pathway activation in human uterine leiomyomas

21 January 2018

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Insulin receptor tyrosine kinase activity and substrate 1 (IRS-1) expression in human myometrium and leiomyoma

21 January 2018

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Reactive oxygen species mediate mitogenic growth factor signaling pathways in human leiomyoma smooth muscle cells

21 January 2018

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https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Differential expression of Akt/protein kinase B, Bcl-2 and Bax proteins in human leiomyoma and myometrium

21 January 2018

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Molecular mechanisms involved in GnRH analogue-related apoptosis for uterine leiomyomas

21 January 2018

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Antiproliferative and proapoptotic effects of raloxifene on uterine leiomyomas in postmenopausal women

21 January 2018

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Expression profile of tuberin and some potential tumorigenic factors in 60 patients with uterine leiomyomata

21 January 2018

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https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Expression of insulin-like growth factors (IGFs) and IGF signaling: molecular complexity in uterine leiomyomas.

21 January 2018

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21 January 2018

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Comparison of human and rat uterine leiomyomata: identification of a dysregulated mammalian target of rapamycin pathway.

21 January 2018

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https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Progestins activate the AKT pathway in leiomyoma cells and promote survival.

21 January 2018

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Expression of selected tumor suppressor and oncogenes in endometrium of women with endometriosis.

21 January 2018

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https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Expression of estrogen receptor alpha and beta in peritoneal and ovarian endometriosis

21 January 2018

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https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Serial analysis of gene expression reveals differential expression between endometriosis and normal endometrium. Possible roles for AXL and SHC1 in the pathogenesis of endometriosis

21 January 2018

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https://api.crossref.org/works/10.3109%2F09513590.2011.583955

17betaE2 promotes cell proliferation in endometriosis by decreasing PTEN via NFkappaB-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Possible pathophysiological roles of mitogen-activated protein kinases (MAPKs) in endometriosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Selective inhibition of prostaglandin E2 receptors EP2 and EP4 induces apoptosis of human endometriotic cells through suppression of ERK1/2, AKT, NFkappaB, and beta-catenin pathways and activation of intrinsic apoptotic mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Increased mitogen-activated protein kinase kinase/extracellularly regulated kinase activity in human endometrial stromal fibroblasts of women with endometriosis reduces 3',5'-cyclic adenosine 5'-monophosphate inhibition of cyclin D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Reactive oxygen species controls endometriosis progression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Transcriptional characterizations of differences between eutopic and ectopic endometrium

21 January 2018

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https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Differential regulation of Akt phosphorylation in endometriosis

21 January 2018

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https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Endometriotic stromal cells lose the ability to regulate cell-survival signaling in endometrial epithelial cells in vitro

21 January 2018

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https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Estrogen receptor-alpha gene (T/C) Pvu II polymorphism in endometriosis and uterine fibroids

21 January 2018

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https://api.crossref.org/works/10.3109%2F09513590.2011.583955

Polycystic ovary syndrome and risk of uterine leiomyomata

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F09513590.2011.583955

10.3109/09513590.2011.583955

21 January 2018

Identifiers

DOI

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25 August 2017

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