Bench-to-beside review: acute-on-chronic liver failure - linking the gut, liver and systemic circulation (Q37959188)

25 August 2017

2 references

21 March 2019

8 April 2021

Bench-to-beside review: acute-on-chronic liver failure - linking the gut, liver and systemic circulation (English)

1 reference

25 August 2017

end-stage liver disease

2 references

21 March 2019

8 April 2021

1 reference

8 April 2021

3

Wim Laleman

0 references

author name string

Len Verbeke

series ordinal

1

1 reference

25 August 2017

Frederik Nevens

series ordinal

2

1 reference

25 August 2017

Wim Laleman

series ordinal

3

1 reference

25 August 2017

25 October 2011

3 references

25 August 2017

21 March 2019

8 April 2021

3 references

25 August 2017

21 March 2019

8 April 2021

15

1 reference

25 August 2017

233

1 reference

25 August 2017

5

1 reference

https://scigraph.springernature.com/pub.10.1186/cc10424

25 August 2017

0 references

cites work

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Acute-on-chronic liver failure: the kidneys

6 September 2017

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Gut microbiota and probiotics in chronic liver diseases

6 September 2017

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6 September 2017

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The effect of statins on mortality from severe infections and sepsis: a systematic review and meta-analysis

6 September 2017

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Anti-inflammatory pathways and alcoholic liver disease: role of an adiponectin/interleukin-10/heme oxygenase-1 pathway

6 September 2017

1 reference

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Alcoholic liver disease and the gut-liver axis

6 September 2017

1 reference

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Innate immune dysfunction in acute and chronic liver disease

6 September 2017

1 reference

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The hepatic microcirculation: mechanistic contributions and therapeutic targets in liver injury and repair

6 September 2017

1 reference

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Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL).

6 September 2017

1 reference

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Monocytes and macrophages as cellular targets in liver fibrosis

6 September 2017

1 reference

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Understanding and treating patients with alcoholic cirrhosis: an update.

6 September 2017

1 reference

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Role of Toll-like receptors 2, 4, and 9 in mediating neutrophil dysfunction in alcoholic hepatitis

6 September 2017

1 reference

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NK and NKT cells in liver injury and fibrosis

6 September 2017

1 reference

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The importance of immune dysfunction in determining outcome in acute liver failure

6 September 2017

1 reference

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The measurement and clinical significance of intestinal permeability.

6 September 2017

1 reference

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Toll-like receptors and adaptor molecules in liver disease: update

6 September 2017

1 reference

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Randomized controlled study of extracorporeal albumin dialysis for hepatic encephalopathy in advanced cirrhosis.

6 September 2017

1 reference

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Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists

6 September 2017

1 reference

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Role of Kupffer cells in host defense and liver disease

6 September 2017

1 reference

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Effect of the molecular adsorbent recirculating system and Prometheus devices on systemic haemodynamics and vasoactive agents in patients with acute-on-chronic alcoholic liver failure

6 September 2017

1 reference

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Review article: non-biological liver support in liver failure.

6 September 2017

1 reference

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Portal hypertension: from pathophysiology to clinical practice

6 September 2017

1 reference

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Outcome from molecular adsorbent recycling system (MARS) liver dialysis following drug-induced liver failure

6 September 2017

1 reference

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Flares in chronic hepatitis B patients induced by the host or the virus? Relation to treatment response during Peg-interferon {alpha}-2b therapy

6 September 2017

1 reference

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Sepsis in cirrhosis: report on the 7th meeting of the International Ascites Club.

6 September 2017

1 reference

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Bacterial translocation (BT) in cirrhosis

6 September 2017

1 reference

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Tezosentan, an endothelin receptor antagonist, limits liver injury in endotoxin challenged cirrhotic rats

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Gut microflora in the pathogenesis of the complications of cirrhosis

6 September 2017

1 reference

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Small intestinal bacterial overgrowth in human cirrhosis is associated with systemic endotoxemia

6 September 2017

1 reference

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The pathophysiological basis of acute-on-chronic liver failure

6 September 2017

1 reference

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Acute-on-chronic liver failure: pathophysiological basis of therapeutic options

6 September 2017

1 reference

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Hepatic blood flow regulation by stellate cells in normal and injured liver

6 September 2017

1 reference

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Role of interleukin-13 in innate and adaptive immunity.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Bacterial translocation in cirrhotic rats stimulates eNOS-derived NO production and impairs mesenteric vascular contractility

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Small intestine dysmotility and bacterial overgrowth in cirrhotic patients with spontaneous bacterial peritonitis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Dialysis against a recycled albumin solution enables the removal of albumin-bound toxins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Blood polymorphonuclear dysfunction in patients with alcoholic cirrhosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Treatment with the leukotriene inhibitor montelukast for 10 days attenuates portal hypertension in rat liver cirrhosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Attenuation of toll-like receptor 2-mediated innate immune response in patients with alcoholic chronic liver disease

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Intraperitoneal LPS amplifies portal hypertension in rat liver fibrosis.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

In vivo gene transfer of endothelial nitric oxide synthase decreases portal pressure in anaesthetised carbon tetrachloride cirrhotic rats

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

The effect of endothelin and its antagonist Bosentan on hemodynamics and microvascular exchange in cirrhotic rat liver

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Cellular localization of endothelin-1 and increased production in liver injury in the rat: potential for autocrine and paracrine effects on stellate cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Bacterial translocation in the portal-hypertensive rat: studies in basal conditions and on exposure to hemorrhagic shock

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Expression patterns of leukocyte adhesion ligand molecules on human liver endothelia. Lack of ELAM-1 and CD62 inducibility on sinusoidal endothelia and distinct distribution of VCAM-1, ICAM-1, ICAM-2, and LFA-3.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Evidence against a role for inducible nitric oxide synthase in the hyperdynamic circulation of portal-hypertensive rats.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Comparison of translocation rates of various indigenous bacteria from the gastrointestinal tract to the mesenteric lymph node.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

A randomized trial of prednisolone in patients with severe alcoholic hepatitis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Bacterial DNA translocation is associated with systemic circulatory abnormalities and intrahepatic endothelial dysfunction in patients with cirrhosis.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Alcohol takes the toll on immune function

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Kupffer cell activation by hydrogen peroxide: a new mechanism of portal pressure increase

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Pentoxifylline does not decrease short-term mortality but does reduce complications in patients with advanced cirrhosis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

NCX-1000, a nitric oxide-releasing derivative of UDCA, does not decrease portal pressure in patients with cirrhosis: results of a randomized, double-blind, dose-escalating study.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

The systemic inflammatory response syndrome in cirrhotic patients: relationship with their in-hospital outcome.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Intestinal decontamination improves liver haemodynamics in patients with alcohol-related decompensated cirrhosis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Effect of early bosentan administration on the development of esophageal varices in cirrhotic rats: experimental study in Wistar rats

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Bacterial translocation increases phagocytic activity of polymorphonuclear leucocytes in portal hypertension: priming independent of liver cirrhosis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Results of European post-marketing surveillance of bosentan in pulmonary hypertension.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Role of Kupffer cells in the pathogenesis of liver disease

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

The detection of bacterial DNA in blood of rats with CCl4-induced cirrhosis with ascites represents episodes of bacterial translocation.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Statins and sepsis in patients with cardiovascular disease: a population-based cohort analysis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Norfloxacin reduces aortic NO synthases and proinflammatory cytokine up-regulation in cirrhotic rats: role of Akt signaling

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Bosentan therapy for portopulmonary hypertension

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Kupffer cell-depleted rats have a diminished acute-phase response following major liver resection.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Simvastatin enhances hepatic nitric oxide production and decreases the hepatic vascular tone in patients with cirrhosis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

NCX-1000, a nitric oxide-releasing derivative of ursodeoxycholic acid, ameliorates portal hypertension and lowers norepinephrine-induced intrahepatic resistance in the isolated and perfused rat liver

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Intestinal permeability is increased in patients with advanced cirrhosis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Anti-tumor necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Potentiated hepatic microcirculatory response to endothelin-1 during polymicrobial sepsis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Hepatitis E virus superinfection in patients with chronic liver disease

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Kupffer cell activation after no-flow ischemia versus hemorrhagic shock

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Role of shear stress in aortic eNOS up-regulation in rats with biliary cirrhosis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Intestinal mucosal alterations in experimental cirrhosis in the rat: role of oxygen free radicals

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Beneficial hemodynamic effects of bosentan, a mixed ET(A) and ET(B) receptor antagonist, in portal hypertensive rats.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Endotoxin pretreatment enhances portal venous contractile response to endothelin-1.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Nitroflurbiprofen, a nitric oxide-releasing cyclooxygenase inhibitor, improves cirrhotic portal hypertension in rats

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334742

Upregulation of TNF-alpha production signaling pathways in monocytes from patients with advanced cirrhosis: Possible role of Akt and IRAK-M

1 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FCC10424

A liver-specific nitric oxide donor improves the intra-hepatic vascular response to both portal blood flow increase and methoxamine in cirrhotic rats

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FCC10424

Blood neutrophil functions and cytokine release in severe alcoholic hepatitis: effect of corticosteroids

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FCC10424

Regulation of human monocyte functions by acute ethanol treatment: decreased tumor necrosis factor-alpha, interleukin-1 beta and elevated interleukin-10, and transforming growth factor-beta production

21 January 2018

1 reference

12 December 2020

Kupffer cell blockade improves the endotoxin-induced microcirculatory inflammatory response in obstructive jaundice

1 reference

12 December 2020

Neutrophil activation in chronic liver disease

1 reference

12 December 2020

Both Ca2+ -dependent and -independent pathways are involved in rat hepatic stellate cell contraction and intrahepatic hyperresponsiveness to methoxamine

1 reference

12 December 2020

Upregulation of endothelial constitutive NOS: a major role in the increased NO production in cirrhotic rats

1 reference

12 December 2020

Detection and identification of bacterial DNA in patients with cirrhosis and culture-negative, nonneutrocytic ascites

1 reference

12 December 2020

Bacterial translocation of enteric organisms in patients with cirrhosis

1 reference

12 December 2020

Increased endothelial nitric oxide synthase activity in the hyperemic vessels of portal hypertensive rats

1 reference

12 December 2020

Regulation of hepatic blood flow during resuscitation from hemorrhagic shock: role of NO and endothelins

1 reference

12 December 2020

Endotoxemia contributes to the immune paralysis in patients with cirrhosis

1 reference

12 December 2020

Bacterial translocation to mesenteric lymph nodes is increased in cirrhotic rats with ascites

1 reference

12 December 2020

Patients with acute on chronic liver failure display "sepsis-like" immune paralysis

1 reference

12 December 2020

Inactivation of Kupffer cells prevents early alcohol-induced liver injury

1 reference

12 December 2020

Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species

1 reference

12 December 2020

Bacterial translocation in acute and chronic portal hypertension

1 reference

12 December 2020

Increased gut permeability after hemorrhage is associated with upregulation of local and systemic IL-6

1 reference

12 December 2020

Early features of acute-on-chronic alcoholic liver failure: a prospective cohort study

1 reference

12 December 2020

Involvement of Kupffer cells in the interaction between neutrophils and sinusoidal endothelial cells in rats

1 reference

12 December 2020

Identifiers

DOI

10.1186/CC10424

1 reference

Dimensions Publication ID

25 August 2017

0 references

1 reference

25 August 2017

1 reference