Hepatobiliary membrane transporters in primary biliary cirrhosis (Q37969179)

26 August 2017

Hepatobiliary membrane transporters in primary biliary cirrhosis (English)

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primary biliary cholangitis

26 August 2017

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author name string

Yasuaki Takeyama

series ordinal

1

1 reference

PubMed ID

22175826

26 August 2017

Shotaro Sakisaka

series ordinal

2

1 reference

26 August 2017

19 December 2011

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26 August 2017

1 reference

26 August 2017

42

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26 August 2017

2

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26 August 2017

120-130

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Bile acid transporters in health and disease

26 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Nuclear DNA fragmentation and expression of Bcl-2 in primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Alterations in tight junctions differ between primary biliary cirrhosis and primary sclerosing cholangitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Molecular pathogenesis of cholestasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Identification and functional characterization of the promoter region of the human organic anion transporting polypeptide gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Expression of hepatic transporters OATP-C and MRP2 in primary sclerosing cholangitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Hepatocyte nuclear factor-4alpha is a central transactivator of the mouse Ntcp gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

The human Na+-taurocholate cotransporting polypeptide gene is activated by glucocorticoid receptor and peroxisome proliferator-activated receptor-gamma coactivator-1alpha, and suppressed by bile acids via a small heterodimer partner-dependent mechan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

"Don't know much bile-ology"

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Sustained upregulation of sodium taurocholate cotransporting polypeptide and bile salt export pump and downregulation of cholesterol 7α-hydroxylase in the liver of patients with end-stage primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Feed-forward regulation of bile acid detoxification by CYP3A4: studies in humanized transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Role of retinoid-X receptor-alpha in the suppression of rat bile acid coenzyme A-amino acid N-acyltransferase in liver during sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Chenodeoxycholic acid-mediated activation of the farnesoid X receptor negatively regulates hydroxysteroid sulfotransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Bile Acid sulfation: a pathway of bile acid elimination and detoxification

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

The human bile salt export pump: characterization of substrate specificity and identification of inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Alternative transporter pathways in patients with untreated early-stage and late-stage primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Identification of a nuclear receptor for bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Effects of bile salt flux variations on the expression of hepatic bile salt transporters in vivo in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

The state of cholesterol metabolism in the liver of patients with primary biliary cirrhosis: the role of MDR3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

High expression of MDR1, MRP1, and MRP3 in the hepatic progenitor cell compartment and hepatocytes in severe human liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Nuclear receptors RXRalpha:RARalpha are repressors for human MRP3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Changes of organic anion transporter MRP4 and related nuclear receptors in human obstructive cholestasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Structure and function of the human breast cancer resistance protein (BCRP/ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Breast cancer resistance protein (BCRP/ABCG2) is expressed by progenitor cells/reactive ductules and hepatocytes and its expression pattern is influenced by disease etiology and species type: possible functional consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Role of breast cancer resistance protein in the adaptive response to cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

New molecular insights into the mechanisms of cholestasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

Farnesoid X receptor agonists for primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1872-034X.2011.00912.X

10.1111/J.1872-034X.2011.00912.X

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22175826