Clozapine, atypical antipsychotics, and the benefits of fast-off D2 dopamine receptor antagonism (Q37983747)

26 August 2017

Clozapine, atypical antipsychotics, and the benefits of fast-off D2 dopamine receptor antagonism (English)

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26 August 2017

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Georges Vauquelin

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26 August 2017

Sophie Bostoen

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2

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26 August 2017

Patrick Vanderheyden

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3

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26 August 2017

Philip Seeman

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4

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26 August 2017

14 February 2012

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Naunyn-Schmiedeberg's Archives of Pharmacology

26 August 2017

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26 August 2017

385

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26 August 2017

4

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26 August 2017

337-372

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https://scigraph.springernature.com/pub.10.1007/s00210-012-0734-2

26 August 2017

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Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Absence of receptor reserve at striatal dopamine receptors regulating cholinergic neuronal activity

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From motivation to action: functional interface between the limbic system and the motor system.

21 January 2018

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21 January 2018

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21 January 2018

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Evaluation of dopamine D-2 receptor occupancy by clozapine, risperidone, and haloperidol in vivo in the rodent and nonhuman primate brain using 18F-fallypride

21 January 2018

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In vivo vulnerability to competition by endogenous dopamine: comparison of the D2 receptor agonist radiotracer (-)-N-[11C]propyl-norapomorphine ([11C]NPA) with the D2 receptor antagonist radiotracer [11C]-raclopride

21 January 2018

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Measurement of the proportion of D2 receptors configured in state of high affinity for agonists in vivo: a positron emission tomography study using [11C]N-propyl-norapomorphine and [11C]raclopride in baboons

21 January 2018

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Mechanism of agonist and antagonist binding to alpha 2 adrenergic receptors: evidence for a precoupled receptor-guanine nucleotide protein complex.

21 January 2018

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Dopamine D2 receptor dimers and receptor-blocking peptides

21 January 2018

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The influence of G protein subtype on agonist action at D2 dopamine receptors

21 January 2018

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Time course of D2-dopamine receptor occupancy examined by PET after single oral doses of haloperidol

21 January 2018

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Heterotrimeric G protein activation by G-protein-coupled receptors

21 January 2018

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Using pharmacokinetic-pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics

21 January 2018

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Does clozapine work by blocking spikes and sparing bursts?

21 January 2018

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Potentials and pitfalls using high affinity radioligands in PET and SPET determinations on regional drug induced D2 receptor occupancy--a simulation study based on experimental data

21 January 2018

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New determinants of receptor-effector coupling: trafficking and compartmentation in membrane microdomains.

21 January 2018

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Antagonist-radioligand binding to D2L-receptors in intact cells

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21 January 2018

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Non-competitive interaction between raclopride and spiperone on human D-receptors in intact Chinese hamster ovary cells

21 January 2018

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Estimation of the dissociation rate of unlabelled ligand-receptor complexes by a 'two-step' competition binding approach

21 January 2018

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Internalization of D2 dopamine receptors is clathrin-dependent and select to dendro-axonic appositions in primate prefrontal cortex.

21 January 2018

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Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as D2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (huntexil, pridopidine, ACR16).

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Classical and new roles of beta-arrestins in the regulation of G-protein-coupled receptors

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Lipid rafts: bringing order to chaos

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21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Mechanisms of inverse agonist action at D2 dopamine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Investigation of the mechanism of agonist and inverse agonist action at D2 dopamine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Mechanisms of agonist action at D2 dopamine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Anatomically distinct dopamine release during anticipation and experience of peak emotion to music

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

The search for novel antipsychotics: pharmacological and molecular targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Multiple Dopamine Functions at Different Time Courses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

An update of fast-off dopamine D2 atypical antipsychotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Dopamine D2High receptors measured ex vivo are elevated in amphetamine-sensitized animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

All Roads to Schizophrenia Lead to Dopamine Supersensitivity and Elevated Dopamine D2High Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Rapid release of antipsychotic drugs from dopamine D2 receptors: an explanation for low receptor occupancy and early clinical relapse upon withdrawal of clozapine or quetiapine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Deriving the therapeutic concentrations for clozapine and haloperidol: the apparent dissociation constant of a neuroleptic at the dopamine D2 or D4 receptor varies with the affinity of the competing radioligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Brain receptors for antipsychotic drugs and dopamine: direct binding assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Antipsychotic drug doses and neuroleptic/dopamine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

The cloned dopamine D2 receptor reveals different densities for dopamine receptor antagonist ligands. Implications for human brain positron emission tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

New dopamine receptor, D2(Longer), with unique TG splice site, in human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Amphetamine-sensitized animals show a marked increase in dopamine D2 high receptors occupied by endogenous dopamine, even in the absence of acute challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Dopamine displaces [3H]domperidone from high-affinity sites of the dopamine D2 receptor, but not [3H]raclopride or [3H]spiperone in isotonic medium: Implications for human positron emission tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Psychosis pathways converge via D2high dopamine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: a comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Anatomical substrates for glutamate-dopamine interactions: evidence for specificity of connections and extrasynaptic actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Influence of the beta-adrenergic receptor concentration on functional coupling to the adenylate cyclase system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2 and D3 dopamine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Risperidone irreversibly binds to and inactivates the h5-HT7 serotonin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Diffusion delays and unstirred layer effects at monolayer cultures of Chinese hamster ovary cells: radioligand binding, confocal microscopy, and mathematical simulations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Clozapine can induce high dopamine D(2) receptor occupancy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Biochemical mechanisms of drug action: what does it take for success?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Biochemical mechanisms of New Molecular Entities (NMEs) approved by United States FDA during 2001-2004: mechanisms leading to optimal efficacy and safety

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Molecular mechanisms for the persistent bronchodilatory effect of the beta 2-adrenoceptor agonist salmeterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Receptor reserve-dependent properties of antipsychotics at human dopamine D2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

No support for regional selectivity in clozapine-treated patients: a PET study with [(11)C]raclopride and [(11)C]FLB 457.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Significant dissociation of brain and plasma kinetics with antipsychotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Residence time of receptor-ligand complexes and its effect on biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Elevation of prolactin levels by atypical antipsychotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Paracrine transactivation of the CB1 cannabinoid receptor by AT1 angiotensin and other Gq/11 protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Distinct functions of the two isoforms of dopamine D2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Rebinding: or why drugs may act longer in vivo than expected from their in vitro target residence time

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Long-lasting target binding and rebinding as mechanisms to prolong in vivo drug action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Ligands, their receptors and ... plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Kinetic versus allosteric mechanisms to explain insurmountable antagonism and delayed ligand dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Slow antagonist dissociation and long-lasting in vivo receptor protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

A two-state receptor model for the interaction between angiotensin II type 1 receptors and non-peptide antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Models and methods for studying insurmountable antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

New insights in insurmountable antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Long-lasting angiotensin type 1 receptor binding and protection by candesartan: comparison with other biphenyl-tetrazole sartans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Site-directed mutagenesis at the human B2 receptor and molecular modelling to define the pharmacophore of non-peptide bradykinin receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Dopamine D2 and D4 receptor ligands: relation to antipsychotic action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Extrastriatal and striatal D(2) dopamine receptor blockade with haloperidol or new antipsychotic drugs in patients with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Immunocytochemical localization of D1 and D2 dopamine receptors in the basal ganglia of the rat: light and electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Binding kinetics and mechanism of action: toward the discovery and development of better and best in class drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Distinct Roles for Gαi2, Gαi3, and Gβγ in Modulation of Forskolin- or Gs-mediated cAMP Accumulation and Calcium Mobilization by Dopamine D2S Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0734-2

Behavioral and radioligand binding evidence for irreversible dopamine receptor blockade by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline

21 January 2018

1 reference

12 December 2020

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1 reference

12 December 2020

The dynamics of drug-target interactions: drug-target residence time and its impact on efficacy and safety

1 reference

12 December 2020

A dopaminergic deficit hypothesis of schizophrenia: the path to discovery

1 reference

12 December 2020

The classification of seven transmembrane receptors in recombinant expression systems

1 reference

12 December 2020

Occupancy of dopamine D2 receptors by the atypical antipsychotic drugs risperidone and olanzapine: theoretical implications.

1 reference

12 December 2020

D2 dopamine receptors in striatal medium spiny neurons reduce L-type Ca2+ currents and excitability via a novel PLC[beta]1-IP3-calcineurin-signaling cascade.

1 reference

12 December 2020

Dopaminergic receptors in the anterior pituitary gland. Correlation of [3H]dihydroergocryptine binding with the dopaminergic control of prolactin release

1 reference

12 December 2020

Basic concepts of pharmacokinetic/pharmacodynamic (PK/PD) modelling

1 reference

12 December 2020

Comparison of the ligand binding and signaling properties of human dopamine D(2) and D(3) receptors in Chinese hamster ovary cells.

1 reference

12 December 2020

Functional coupling of the human dopamine D2 receptor with G alpha i1, G alpha i2, G alpha i3 and G alpha o G proteins: evidence for agonist regulation of G protein selectivity

1 reference

12 December 2020

Dopamine D2(High) receptors on intact cells

1 reference

12 December 2020

Analytical method for simultaneously measuring ex vivo drug receptor occupancy and dissociation rate: application to (R)-dimethindene occupancy of central histamine H1 receptors.

1 reference

12 December 2020

Relationship between receptor occupancy and response at striatal dopamine autoreceptors

1 reference

12 December 2020

Some quantitative uses of drug antagonists

1 reference

12 December 2020

Transfected D2 dopamine receptors mediate the potentiation of arachidonic acid release in Chinese hamster ovary cells

1 reference

12 December 2020

Antipsychotic agents differ in how fast they come off the dopamine D2 receptors. Implications for atypical antipsychotic action

1 reference

12 December 2020

Clozapine. A novel antipsychotic agent

1 reference

12 December 2020

Atypical antipsychotics: mechanism of action.

1 reference

12 December 2020

Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia

1 reference

12 December 2020

Candesartan (CV-11974) dissociates slowly from the angiotensin AT1 receptor

1 reference

12 December 2020

A historical perspective of clozapine.

1 reference

12 December 2020

The kinetics of competitive radioligand binding predicted by the law of mass action.

1 reference

12 December 2020

Scintillation proximity assay as a high-throughput method to identify slowly dissociating nonpeptide ligand binding to the GnRH receptor

1 reference

12 December 2020

Stoichiometry and compartmentation in G protein-coupled receptor signaling: implications for therapeutic interventions involving G(s).

1 reference

12 December 2020

Interactions of novel dopaminergic ligands with D-1 and D-2 dopamine receptors.

1 reference

12 December 2020

The importance of drug-target residence time.

1 reference

12 December 2020

D2 dopamine receptor activation of potassium channels in identified rat lactotrophs: whole-cell and single-channel recording

1 reference

12 December 2020

Shallow agonist competition binding curves for beta-adrenergic receptors: the role of tight agonist binding

1 reference

12 December 2020

Quantifying the association and dissociation rates of unlabelled antagonists at the muscarinic M3 receptor.

1 reference

12 December 2020

Insurmountable angiotensin AT1 receptor antagonists: the role of tight antagonist binding

1 reference

12 December 2020

The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals

1 reference

12 December 2020

Half a century of antipsychotics and still a central role for dopamine D2 receptors

1 reference

12 December 2020

Sequestration of the short and long isoforms of dopamine D2 receptors expressed in Chinese hamster ovary cells

1 reference

12 December 2020

Dopamine receptor sequences. Therapeutic levels of neuroleptics occupy D2 receptors, clozapine occupies D4

1 reference

12 December 2020

Kinetics of binding of membrane-active drugs to receptor sites. Diffusion-limited rates for a membrane bilayer approach of 1,4-dihydropyridine calcium channel antagonists to their active site.

1 reference

12 December 2020

Dynamic dopamine-antagonist interactions at recombinant human dopamine D(2short) receptor: dopamine-bound versus antagonist-bound receptor states.

1 reference

12 December 2020

Clozapine occupies high levels of dopamine D2 receptors

1 reference

12 December 2020

Activation of heterologously expressed D3 dopamine receptors: comparison with D2 dopamine receptors

1 reference

12 December 2020

Operational models of pharmacological agonism.

1 reference

12 December 2020

Positron emission tomography with (18F)methylspiperone demonstrates D2 dopamine receptor binding differences of clozapine and haloperidol

1 reference

12 December 2020

Molecular properties affecting fast dissociation from the D2 receptor

1 reference

12 December 2020

5-hydroxytryptamine2A receptor inverse agonists as antipsychotics

1 reference

12 December 2020

Agonist-induced desensitization of D2 dopamine receptors in human Y-79 retinoblastoma cells

1 reference

12 December 2020

Differential coupling of dopaminergic D2 receptors expressed in different cell types. Stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis in LtK- fibroblasts, hyperpolarization, and cytosolic-free Ca2+ concentration decrease in GH4C1 cel

1 reference

12 December 2020

Agonist and antagonist binding to alpha 2-adrenergic receptors in purified membranes from human platelets. Implications of receptor-inhibitory nucleotide-binding protein stoichiometry

1 reference

12 December 2020

Characterization of [3H]quinpirole binding to human dopamine D2A and D3 receptors: effects of ions and guanine nucleotides

1 reference

12 December 2020

Electron microscopic analysis of D1 and D2 dopamine receptor proteins in the dorsal striatum and their synaptic relationships with motor corticostriatal afferents

1 reference

12 December 2020

Use of novel antipsychotic drugs

1 reference

12 December 2020

Functionally selective neurochemical afferents and efferents of the mesocorticolimbic and nigrostriatal dopamine system

1 reference

12 December 2020

Estimation of agonist dissociation constants at central presynaptic alpha-2 autoreceptors in the absence of autoinhibition

1 reference

12 December 2020

Effect of saponin and filipin on antagonist binding to AT 1 receptors in intact cells

1 reference

12 December 2020

Antipsychotic-induced alterations in D2 dopamine receptor interacting proteins within the cortex

1 reference

12 December 2020

An introduction to PET and SPECT neuroreceptor quantification models.

1 reference

12 December 2020

The role of binding kinetics in therapeutically useful drug action

1 reference

12 December 2020

Association of candesartan vs losartan with all-cause mortality in patients with heart failure

1 reference

12 December 2020

Coordinated expression of dopamine receptors in neostriatal medium spiny neurons.

1 reference

12 December 2020

Efflux of dopamine from the synaptic cleft in the nucleus accumbens of the rat brain

1 reference

12 December 2020

Multiple receptors coupled to adenylate cyclase regulate Na-H exchange independent of cAMP.

1 reference

12 December 2020

Locking of hormone in the beta-adrenergic receptor by attack on a sulfhydryl in an associated component

1 reference

12 December 2020

The effects of a selective D4 dopamine receptor antagonist (L-745,870) in acutely psychotic inpatients with schizophrenia. D4 Dopamine Antagonist Group

1 reference

12 December 2020

Inactivation of beta-adrenergic receptors by N-ethylmaleimide in S49 lymphoma cells. Agonist induction of functional receptor heterogeneity

1 reference

12 December 2020

Visualization of antipsychotic drug binding to living mesolimbic neurons reveals D2 receptor, acidotropic, and lipophilic components

1 reference

12 December 2020

Compartmentation of receptors and guanine nucleotide-binding proteins in NG108-15 cells: lack of cross-talk in agonist binding among the alpha 2-adrenergic, muscarinic, and opiate receptors.

1 reference

12 December 2020

Therapeutic receptor-blocking concentrations of neuroleptics.

1 reference

12 December 2020

D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-deficient mouse model

1 reference

12 December 2020

PET examination of central D2 dopamine receptor occupancy in relation to extrapyramidal syndromes in patients being treated with neuroleptic drugs.

1 reference

12 December 2020

Quantitation of the guanine nucleotide binding regulatory protein Gs in S49 cell membranes using antipeptide antibodies to alpha s.

1 reference

12 December 2020

Dopamine D3 and D4 receptor antagonists in the treatment of schizophrenia

1 reference

12 December 2020

Haloperidol increases prolactin release and cyclic AMP formation in vitro: inverse agonism at dopamine D2 receptors?

1 reference

12 December 2020

Endothelin ET(B) receptors show different binding profiles in intact cells and cell membrane preparations

1 reference

12 December 2020

Ultrastructural localization of D2 receptor-like immunoreactivity in midbrain dopamine neurons and their striatal targets.

1 reference

12 December 2020

The dissociation rate of unlabelled dopamine antagonists and agonists from the dopamine-D2 receptor, application of an original filter method

1 reference

12 December 2020

Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s)

1 reference

12 December 2020

Atypicality of atypical antipsychotics

1 reference

12 December 2020

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor

1 reference

12 December 2020

Dopamine D2 long receptor-deficient mice display alterations in striatum-dependent functions

1 reference

12 December 2020

Dopamine and serotonin receptors: amino acid sequences, and clinical role in neuroleptic parkinsonism

1 reference

12 December 2020

Mechanistic differences of various AT1-receptor blockers in isolated vessels of different origin

1 reference

12 December 2020

The assessment of antagonist potency under conditions of transient response kinetics

1 reference

12 December 2020

Differential regulation of D2 and D4 dopamine receptor mRNAs in the primate cerebral cortex vs. neostriatum: effects of chronic treatment with typical and atypical antipsychotic drugs.

1 reference

12 December 2020

Dopamine receptor binding on intact cells. Absence of a high-affinity agonist-receptor binding state

1 reference

12 December 2020

The dopamine D2 receptor: two molecular forms generated by alternative splicing

1 reference

12 December 2020

Recombinant aequorin as tool for monitoring calcium concentration in subcellular compartments.

1 reference

12 December 2020

The advantage of using positron emission tomography in drug research

1 reference

12 December 2020

Dopamine D2 receptor stimulation of Na+/H+ exchange assessed by quantification of extracellular acidification

1 reference

12 December 2020

A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model

1 reference

12 December 2020

Clozapine in treatment-resistant schizophrenics

1 reference

12 December 2020

Comparison of withdrawal of typical and atypical antipsychotic drugs: a case study

1 reference

12 December 2020

10.1007/S00210-012-0734-2

Identifiers

DOI

1 reference

26 August 2017

1 reference