Novel pathways and therapies in experimental diabetic atherosclerosis (Q37990618)

26 August 2017

Novel pathways and therapies in experimental diabetic atherosclerosis (English)

1 reference

26 August 2017

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Christine Koulis

1

1 reference

PubMed ID

22390805

26 August 2017

Judy B de Haan

series ordinal

2

1 reference

PubMed ID

22390805

26 August 2017

Terri J Allen

series ordinal

3

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26 August 2017

1 March 2012

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Expert Review of Cardiovascular Therapy

26 August 2017

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26 August 2017

10

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26 August 2017

323-335

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26 August 2017

3

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Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial

26 August 2017

1 reference

Irbesartan but not amlodipine suppresses diabetes-associated atherosclerosis

21 January 2018

1 reference

Prevention of accelerated atherosclerosis by angiotensin-converting enzyme inhibition in diabetic apolipoprotein E-deficient mice

21 January 2018

1 reference

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

21 January 2018

1 reference

Recipes for creating animal models of diabetic cardiovascular disease

21 January 2018

1 reference

Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators

21 January 2018

1 reference

Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol

21 January 2018

1 reference

Telmisartan, ramipril, or both in patients at high risk for vascular events

21 January 2018

1 reference

Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE): rationale and study design

21 January 2018

1 reference

Angiotensin type 2 receptor antagonism confers renal protection in a rat model of progressive renal injury

21 January 2018

1 reference

Angiotensin type 2 receptor is expressed in the adult rat kidney and promotes cellular proliferation and apoptosis.

21 January 2018

1 reference

Anti-atherosclerotic and renoprotective effects of combined angiotensin-converting enzyme and neutral endopeptidase inhibition in diabetic apolipoprotein E-knockout mice.

21 January 2018

1 reference

Expression of AT2 receptors in the developing rat fetus

21 January 2018

1 reference

Paradoxical role of angiotensin II type 2 receptors in resistance arteries of old rats

21 January 2018

1 reference

Can angiotensin II type 2 receptors have deleterious effects in cardiovascular disease? Implications for therapeutic blockade of the renin-angiotensin system

21 January 2018

1 reference

A novel angiotensin II type 2 receptor signaling pathway: possible role in cardiac hypertrophy

21 January 2018

1 reference

The angiotensin II type 2 receptor causes constitutive growth of cardiomyocytes and does not antagonize angiotensin II type 1 receptor-mediated hypertrophy

21 January 2018

1 reference

Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice

21 January 2018

1 reference

Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction?

21 January 2018

1 reference

Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes

21 January 2018

1 reference

Angiotensin II subtype 2 receptor blockade and deficiency attenuate the development of atherosclerosis in an apolipoprotein E-deficient mouse model of diabetes.

21 January 2018

1 reference

Oxidative stress and diabetic vascular complications

21 January 2018

1 reference

Biochemistry and molecular cell biology of diabetic complications

21 January 2018

1 reference

Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy

21 January 2018

1 reference

Vascular NADPH oxidases as drug targets for novel antioxidant strategies

21 January 2018

1 reference

Novel therapies targeting vascular endothelium

21 January 2018

1 reference

Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial

21 January 2018

1 reference

Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial

21 January 2018

1 reference

Vitamin E increases the risk of developing heart failure after myocardial infarction: Results from the GISSI-Prevenzione trial.

21 January 2018

1 reference

The ambivalence of vitamin E in atherogenesis

21 January 2018

1 reference

Molecular action of vitamin E in lipoprotein oxidation: implications for atherosclerosis

21 January 2018

1 reference

A review on the role of antioxidants in the management of diabetes and its complications

21 January 2018

1 reference

Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.

21 January 2018

1 reference

Glutathione Peroxidase 1 Activity and Cardiovascular Events in Patients with Coronary Artery Disease

21 January 2018

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Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in japanese type 2 diabetic patients

21 January 2018

1 reference

Glutathione peroxidase 1 genotype is associated with an increased risk of coronary artery disease

21 January 2018

1 reference

Responsiveness of selenoproteins to dietary selenium

21 January 2018

1 reference

Ebselen, a selenoorganic compound as glutathione peroxidase mimic

21 January 2018

1 reference

Effect of glutathione peroxidase mimic ebselen (PZ51) on endothelium and vascular structure of stroke-prone spontaneously hypertensive rats.

21 January 2018

1 reference

Ebselen decreases oxygen free radical production and iron concentrations in the hearts of chronically iron-overloaded mice

21 January 2018

1 reference

Site-specific antiatherogenic effect of the antioxidant ebselen in the diabetic apolipoprotein E-deficient mouse.

21 January 2018

1 reference

Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse

21 January 2018

1 reference

Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen

21 January 2018

1 reference

Vascular oxidant stress enhances progression and angiogenesis of experimental atheroma

21 January 2018

1 reference

Glutathione peroxidase (GPx)-like antioxidant activity of the organoselenium drug ebselen: unexpected complications with thiol exchange reactions

21 January 2018

1 reference

Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group

21 January 2018

1 reference

Tipping the redox balance of oxidative stress in fibrogenic pathways in chronic kidney disease

21 January 2018

1 reference

Nephropathy in Zucker diabetic fat rat is associated with oxidative and nitrosative stress: prevention by chronic therapy with a peroxynitrite scavenger ebselen

21 January 2018

1 reference

Ebselen attenuates oxidative stress-induced apoptosis via the inhibition of the c-Jun N-terminal kinase and activator protein-1 signalling pathway in PC12 cells

21 January 2018

1 reference

Ebselen inhibits tumor necrosis factor-alpha-induced c-Jun N-terminal kinase activation and adhesion molecule expression in endothelial cells.

21 January 2018

1 reference

Ebselen inhibits p38 mitogen-activated protein kinase-mediated endothelial cell death by hydrogen peroxide

21 January 2018

1 reference

Reactive oxygen species as mediators of signal transduction in cardiovascular disease

21 January 2018

1 reference

Activation of the ROCK1 branch of the transforming growth factor-beta pathway contributes to RAGE-dependent acceleration of atherosclerosis in diabetic ApoE-null mice

21 January 2018

1 reference

Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts

21 January 2018

1 reference

Receptor for advanced glycation end products mediates inflammation and enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice.

21 January 2018

1 reference

Oxidative stress, AGE, and atherosclerosis

21 January 2018

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Advanced glycation end product interventions reduce diabetes-accelerated atherosclerosis.

21 January 2018

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A breaker of advanced glycation end products attenuates diabetes-induced myocardial structural changes

21 January 2018

1 reference

RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes

21 January 2018

1 reference

Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice

21 January 2018

1 reference

RAGE mediates oxidized LDL-induced pro-inflammatory effects and atherosclerosis in non-diabetic LDL receptor-deficient mice

21 January 2018

1 reference

Receptor for AGE (RAGE) mediates neointimal formation in response to arterial injury

21 January 2018

1 reference

RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice.

21 January 2018

1 reference

Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease.

21 January 2018

1 reference

Clinical review: The role of advanced glycation end products in progression and complications of diabetes

21 January 2018

1 reference

Effects of HMGB1 on ischemia-reperfusion injury in the rat heart

21 January 2018

1 reference

Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells

21 January 2018

1 reference

High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity

21 January 2018

1 reference

Reversing established sepsis with antagonists of endogenous high-mobility group box 1.

21 January 2018

1 reference

Tissue specificity of nucleo-cytoplasmic distribution of HMG1 and HMG2 proteins and their probable functions.

21 January 2018

1 reference

Increased expression of the DNA-binding cytokine HMGB1 in human atherosclerotic lesions: role of activated macrophages and cytokines.

21 January 2018

1 reference

High-mobility group box protein 1 neutralization reduces development of diet-induced atherosclerosis in apolipoprotein e-deficient mice.

21 January 2018

1 reference

HMGB1: the missing link between diabetes mellitus and heart failure

21 January 2018

1 reference

21 January 2018

1 reference

Effects of hyperglycemia and insulin therapy on high mobility group box 1 in endotoxin-induced acute lung injury in a rat model

21 January 2018

1 reference

Increased toll-like receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjects

21 January 2018

1 reference

Upregulation of RAGE and its ligands in proliferative retinal disease.

21 January 2018

1 reference

Urotensin II: the old kid in town.

21 January 2018

1 reference

Urotensin II promotes hypertrophy of cardiac myocytes via mitogen-activated protein kinases

21 January 2018

1 reference

Urotensin II: a somatostatin-like peptide in the caudal neurosecretory system of fishes

21 January 2018

1 reference

Cloning, sequence analysis and tissue distribution of the mouse and rat urotensin II precursors.

21 January 2018

1 reference

Increased expression of urotensin II and its cognate receptor GPR14 in atherosclerotic lesions of the human aorta

21 January 2018

1 reference

Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14

21 January 2018

1 reference

Increased plasma urotensin-II levels are associated with diabetic retinopathy and carotid atherosclerosis in Type 2 diabetes.

21 January 2018

1 reference

Vasoactive renal factors and the progression of diabetic nephropathy.

21 January 2018

1 reference

Targeted overexpression of the human urotensin receptor transgene in smooth muscle cells: effect of UT antagonism in ApoE knockout mice fed with Western diet

21 January 2018

1 reference

Peroxisome proliferator-activated receptor (PPAR) in metabolic syndrome and type 2 diabetes mellitus

21 January 2018

1 reference

Rosiglitazone attenuates atherosclerosis in a model of insulin insufficiency independent of its metabolic effects

21 January 2018

1 reference

Rosiglitazone evaluated for cardiovascular outcomes--an interim analysis

21 January 2018

1 reference

Comparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: the PERISCOPE randomized controlled trial

21 January 2018

1 reference

The prospective pioglitazone clinical trial in macrovascular events (PROactive): can pioglitazone reduce cardiovascular events in diabetes? Study design and baseline characteristics of 5238 patients

21 January 2018

1 reference

Gemfibrozil decreases atherosclerosis in experimental diabetes in association with a reduction in oxidative stress and inflammation.

21 January 2018

1 reference

Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial

21 January 2018

1 reference

Mitochondria-Targeted Antioxidant MitoQ 10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy

21 January 2018

1 reference

Cellular distribution of immunoreactive urotensin-II in human tissues with evidence of increased expression in atherosclerosis and a greater constrictor response of small compared to large coronary arteries

21 January 2018

1 reference

Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial: Design and Methods

21 January 2018

1 reference

High Glucose Induces Antioxidant Enzymes in Human Endothelial Cells in Culture: Evidence Linking Hyperglycemia and Oxidative Stress

21 January 2018

1 reference

Antioxidant Therapy in Diabetic Complications: What is New?

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/ERC.12.13

1 reference

26 August 2017

1 reference

PubMed ID

22390805