Therapeutic modulation of miRNA for the treatment of proinflammatory lung diseases. (Q37991391)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22397568%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Therapeutic modulation of miRNA for the treatment of proinflammatory lung diseases (English)

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25 January 2020

2

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25 January 2020

Sally-Ann Cryan

4

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25 January 2020

Catherine M Greene

5

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25 January 2020

author name string

Tidi Hassan

1

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25 January 2020

Noel G McElvaney

3

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25 January 2020

publication date

1 March 2012

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Expert Review of Anti-infective Therapy

25 January 2020

published in

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25 January 2020

volume

10

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25 January 2020

issue

3

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25 January 2020

page(s)

359-368

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Mammalian microRNAs predominantly act to decrease target mRNA levels

25 January 2020

cites work

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Processing of primary microRNAs by the Microprocessor complex

21 January 2018

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The Drosha-DGCR8 complex in primary microRNA processing

21 January 2018

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Nuclear export of microRNA precursors

21 January 2018

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MicroRNA biogenesis: coordinated cropping and dicing

21 January 2018

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Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs

21 January 2018

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Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR

21 January 2018

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AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2.

21 January 2018

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Modulation of microRNA processing by p53

21 January 2018

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https://api.crossref.org/works/10.1586%2FERI.11.175

Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules

21 January 2018

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Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

21 January 2018

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Innate immunity in the lungs

21 January 2018

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MicroRNAs modulate hematopoietic lineage differentiation

21 January 2018

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MicroRNA control in the immune system: basic principles

21 January 2018

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MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb

21 January 2018

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MicroRNAs in normal and malignant hematopoiesis

21 January 2018

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microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells

21 January 2018

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https://api.crossref.org/works/10.1586%2FERI.11.175

Inducible microRNA-155 feedback promotes type I IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1.

21 January 2018

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Inositol phosphatase SHIP1 is a primary target of miR-155

21 January 2018

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https://api.crossref.org/works/10.1586%2FERI.11.175

Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells.

21 January 2018

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Identification of MyD88 as a novel target of miR-155, involved in negative regulation of Helicobacter pylori-induced inflammation

21 January 2018

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https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNA-155 is induced during the macrophage inflammatory response

21 January 2018

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https://api.crossref.org/works/10.1586%2FERI.11.175

NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection

21 January 2018

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https://api.crossref.org/works/10.1586%2FERI.11.175

Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

21 January 2018

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https://api.crossref.org/works/10.1586%2FERI.11.175

The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs

21 January 2018

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https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNA-146a feedback inhibits RIG-I-dependent Type I IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Regulation of IKKbeta by miR-199a affects NF-kappaB activity in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNA-466l upregulates IL-10 expression in TLR-triggered macrophages by antagonizing RNA-binding protein tristetraprolin-mediated IL-10 mRNA degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Proteases and antiproteases in chronic neutrophilic lung disease - relevance to drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNAs in inflammatory lung disease--master regulators or target practice?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

miR-126 is downregulated in cystic fibrosis airway epithelial cells and regulates TOM1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Elevated miR-155 promotes inflammation in cystic fibrosis by driving hyperexpression of interleukin-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Innate immunity and asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-type hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Altered expression of microRNA in the airway wall in chronic asthma: miR-126 as a potential therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Let-7 microRNA-mediated regulation of IL-13 and allergic airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNA-146a modulates human bronchial epithelial cell survival in response to the cytokine-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Sequence-specific inhibition of small RNA function

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

microRNAs: Master regulators as potential therapeutics in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

LNA-mediated microRNA silencing in non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Silencing of microRNAs in vivo with 'antagomirs'

21 January 2018

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https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNA replacement therapy for cancer

21 January 2018

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Targeting microRNAs in cancer: rationale, strategies and challenges

21 January 2018

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https://api.crossref.org/works/10.1586%2FERI.11.175

Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Polycistronic RNA polymerase II expression vectors for RNA interference based on BIC/miR-155.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Emerging role of microRNAs in liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Targeted delivery of antisense inhibitor of miRNA for antiangiogenesis therapy using cRGD-functionalized nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Lipidic systems for in vivo siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Pulmonary gene silencing in transgenic EGFP mice using aerosolised chitosan/siRNA nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Lung delivery studies using siRNA conjugated to TAT(48-60) and penetratin reveal peptide induced reduction in gene expression and induction of innate immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Cell-penetrating-peptide-mediated siRNA lung delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Allele-specific targeting of microRNAs to HLA-G and risk of asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Down-regulation of miR-133a contributes to up-regulation of Rhoa in bronchial smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNA expression in human airway smooth muscle cells: role of miR-25 in regulation of airway smooth muscle phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Mechanical stretch up-regulates microRNA-26a and induces human airway smooth muscle hypertrophy by suppressing glycogen synthase kinase-3β

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

MicroRNA let-7f inhibits tumor invasion and metastasis by targeting MYH9 in human gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Regression of murine lung tumors by the let-7 microRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Knock-down of ubiquitin-specific protease 22 by micro-RNA interference inhibits colorectal cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

In vivo microRNA-155 expression influences antigen-specific T cell-mediated immune responses generated by DNA vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Silencing microRNA by interfering nanoparticles in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

A brain-targeted rabies virus glycoprotein-disulfide linked PEI nanocarrier for delivery of neurogenic microRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.11.175

21 January 2018

Homing in on delivery

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https://api.crossref.org/works/10.1586%2FERI.11.175

21 January 2018

Identifiers

DOI

10.1586/ERI.11.175

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22397568%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference