Challenges in development of nanoparticle-based therapeutics (Q37992525)

26 August 2017

5 references

20 June 2019

6 August 2019

19 September 2019

1 October 2019

30 June 2021

Challenges in development of nanoparticle-based therapeutics (English)

1 reference

pharmaceutical preparation

26 August 2017

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1 reference

biomedical investigative technique

6 August 2019

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19 September 2019

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1 October 2019

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30 June 2021

Neil Desai

1

1 reference

26 August 2017

language of work or name

English

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publication date

10 March 2012

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26 August 2017

1 June 2012

5 references

20 June 2019

6 August 2019

19 September 2019

1 October 2019

30 June 2021

6 references

26 August 2017

20 June 2019

6 August 2019

19 September 2019

1 October 2019

30 June 2021

14

1 reference

26 August 2017

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26 August 2017

282-295

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Creative Commons Attribution 4.0 International

26 August 2017

1 reference

https://scigraph.springernature.com/pub.10.1208/s12248-012-9339-4

30 June 2021

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Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes

6 September 2017

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Nanoparticles for drug delivery: the need for precision in reporting particle size parameters

6 September 2017

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Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines.

6 September 2017

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Vesicle size and stability of biomimetic liposomes from 3'-sulfo-Lewis a (SuLea) containing glycolipids

6 September 2017

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Polymer conjugates as anticancer nanomedicines

6 September 2017

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The pinpoint promise of nanoparticle-based drug delivery and molecular diagnosis

6 September 2017

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Albumin-bound paclitaxel: a next-generation taxane

6 September 2017

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Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo

6 September 2017

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Toxic potential of materials at the nanolevel

6 September 2017

1 reference

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Hypersensitivity reactions to the polysorbate contained in recombinant erythropoietin and darbepoietin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326161

Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides

6 September 2017

1 reference

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Novel RGD lipopeptides for the targeting of liposomes to integrin-expressing endothelial and melanoma cells

6 September 2017

1 reference

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Paclitaxel-HSA interaction. Binding sites on HSA molecule.

6 September 2017

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Nanomedicines for overcoming biological barriers.

6 September 2017

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Reduced cardiotoxicity and comparable efficacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX/Doxil) versus conventional doxorubicin for first-line treatment of metastatic breast cancer

6 September 2017

1 reference

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Nanoparticles of biodegradable polymers for clinical administration of paclitaxel

6 September 2017

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Drug delivery and transport to solid tumors

6 September 2017

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Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties

6 September 2017

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From conventional to stealth liposomes: a new frontier in cancer chemotherapy

6 September 2017

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Optimization of the preparation process for human serum albumin (HSA) nanoparticles.

6 September 2017

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Protein transport across the lung epithelial barrier

6 September 2017

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Controlling the physical behavior and biological performance of liposome formulations through use of surface grafted poly(ethylene glycol).

6 September 2017

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Size and structure of spontaneously forming liposomes in lipid/PEG-lipid mixtures

6 September 2017

1 reference

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Ligand-targeted therapeutics in anticancer therapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326161

Effects of high-energy electrons and gamma rays directly on protein molecules

6 September 2017

1 reference

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A comparison of liposomal formulations of doxorubicin with drug administered in free form: changing toxicity profiles

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326161

Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326161

Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326161

Role of formulation vehicles in taxane pharmacology

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326161

Long-circulating and target-specific nanoparticles: theory to practice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326161

X-ray crystal structure of an anti-Buckminsterfullerene antibody Fab fragment: Biomolecular recognition of C60

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326161

Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326161

Caveolin and its cellular and subcellular immunolocalisation in lung alveolar epithelium: implications for alveolar epithelial type I cell function.

6 September 2017

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Antigenicity of fullerenes: antibodies specific for fullerenes and their characteristics

6 September 2017

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Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment

6 September 2017

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Nanoparticles as adjuvants for vaccines.

6 September 2017

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Nanoparticles in drug delivery.

6 September 2017

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Transport of molecules across tumor vasculature

6 September 2017

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Nanoparticle therapeutics: FDA approval, clinical trials, regulatory pathways, and case study

6 September 2017

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Increased antitumor activity, intratumor paclitaxel concentrations, and endothelial cell transport of cremophor-free, albumin-bound paclitaxel, ABI-007, compared with cremophor-based paclitaxel

14 September 2017

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Biochemical and immunological properties of cytokines conjugated to dendritic polymers

14 September 2017

1 reference

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A novel antiangiogenesis therapy using an integrin antagonist or anti-Flk-1 antibody coated 90Y-labeled nanoparticles

14 September 2017

1 reference

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Apoptosis: the physiologic pathway of cell death

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326161

Albumin nanospheres as carriers for passive drug targeting: an optimized manufacturing technique

14 September 2017

1 reference

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Drug delivery: One nanoparticle, one kill

28 September 2017

1 reference

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The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic.

23 June 2018

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Comparative preclinical and clinical pharmacokinetics of a cremophor-free, nanoparticle albumin-bound paclitaxel (ABI-007) and paclitaxel formulated in Cremophor (Taxol).

23 June 2018

1 reference

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In vivo recognition and clearance of red blood cells containing phosphatidylserine in their plasma membranes

23 June 2018

1 reference

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Hypersensitivity reactions from taxol

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326161

Size and surface charge significantly influence the toxicity of silica and dendritic nanoparticles.

23 June 2018

1 reference

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Targeting of tumor endothelium by RGD-grafted PLGA-nanoparticles loaded with paclitaxel

31 August 2018

1 reference

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Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granuloma

31 August 2018

1 reference

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Complement activation by core-shell poly(isobutylcyanoacrylate)-polysaccharide nanoparticles: influences of surface morphology, length, and type of polysaccharide.

31 August 2018

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The effect of freeze-drying with different cryoprotectants and gamma-irradiation sterilization on the characteristics of ciprofloxacin HCl-loaded poly(D,L-lactide-glycolide) nanoparticles

31 August 2018

1 reference

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Phase III trial of liposomal doxorubicin and cyclophosphamide compared with epirubicin and cyclophosphamide as first-line therapy for metastatic breast cancer

31 August 2018

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Influence of PAMAM dendrimers on human red blood cells.

31 August 2018

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Complement activation following first exposure to pegylated liposomal doxorubicin (Doxil): possible role in hypersensitivity reactions

31 August 2018

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Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin

31 August 2018

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Modulation of lymphatic distribution of subcutaneously injected poloxamer 407-coated nanospheres: the effect of the ethylene oxide chain configuration

31 August 2018

1 reference

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Role of complement activation in hypersensitivity reactions to doxil and hynic PEG liposomes: experimental and clinical studies

31 August 2018

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Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size.

31 August 2018

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Complement dependent immune phagocytosis. I. Requirements for C'1, C'4, C'2, C'3.

31 August 2018

1 reference

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Hemolytic Effects of Water-Soluble Fullerene Derivatives

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326161

Formulation and antitumor activity evaluation of nanocrystalline suspensions of poorly soluble anticancer drugs

3 December 2018

1 reference

12 December 2020

PEGylated liposomes elicit an anti-PEG IgM response in a T cell-independent manner

1 reference

12 December 2020

Anti-PEG IgM elicited by injection of liposomes is involved in the enhanced blood clearance of a subsequent dose of PEGylated liposomes

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12 December 2020

Nanoparticles with decreasing surface hydrophobicities: influence on plasma protein adsorption

1 reference

12 December 2020

In situ preparation of magnetic nonviral gene vectors and magnetofection in vitro

1 reference

12 December 2020

Role of extracellular matrix assembly in interstitial transport in solid tumors

1 reference

12 December 2020

Doxorubicin in sterically stabilized liposomes

1 reference

12 December 2020

Preparation of sub-100 nm human serum albumin nanospheres using a pH-coacervation method

1 reference

12 December 2020

10.1208/S12248-012-9339-4

Identifiers

DOI

1 reference

Dimensions Publication ID

26 August 2017

0 references

1 reference

26 August 2017

1 reference