A mirror of two faces: Lin28 as a master regulator of both miRNA and mRNA. (Q37998956)

26 August 2017

A mirror of two faces: Lin28 as a master regulator of both miRNA and mRNA. (English)

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26 August 2017

Yingqun Huang

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PubMed ID

22467269

26 August 2017

language of work or name

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29 March 2012

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Wiley interdisciplinary reviews. RNA

26 August 2017

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26 August 2017

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26 August 2017

483-494

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26 August 2017

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Heterochronic mutants of the nematode Caenorhabditis elegans.

26 August 2017

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The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA

21 January 2018

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Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites

21 January 2018

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Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies

21 January 2018

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Genetic analysis of the role of the reprogramming gene LIN-28 in human embryonic stem cells

21 January 2018

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The transcriptome profile of human embryonic stem cells as defined by SAGE

21 January 2018

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TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation

21 January 2018

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Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells.

21 January 2018

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The Lin28/let-7 axis regulates glucose metabolism

21 January 2018

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Lin28 promotes transformation and is associated with advanced human malignancies

21 January 2018

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Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma

21 January 2018

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Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II.

21 January 2018

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Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer

21 January 2018

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LIN28B promotes colon cancer progression and metastasis

21 January 2018

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LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms

21 January 2018

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A Yin-Yang balancing act of the lin28/let-7 link in tumorigenesis

21 January 2018

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Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells

21 January 2018

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Emerging paradigms of regulated microRNA processing

21 January 2018

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Regulation of pre-miRNA Processing.

21 January 2018

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Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules

21 January 2018

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A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

21 January 2018

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Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells

21 January 2018

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Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.

21 January 2018

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Selective blockade of microRNA processing by Lin28

21 January 2018

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Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

21 January 2018

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Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA

21 January 2018

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Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.

21 January 2018

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Extensive post-transcriptional regulation of microRNAs and its implications for cancer

21 January 2018

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Human embryonic stem cells express a unique set of microRNAs

21 January 2018

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Post-transcriptional regulation of the let-7 microRNA during neural cell specification

21 January 2018

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LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans

21 January 2018

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Primary microRNA transcripts are processed co-transcriptionally.

21 January 2018

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Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function

21 January 2018

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Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells

21 January 2018

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LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans

21 January 2018

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The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

21 January 2018

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A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing

21 January 2018

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Importance of the NCp7-like domain in the recognition of pre-let-7g by the pluripotency factor Lin28.

21 January 2018

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Molecular basis for interaction of let-7 microRNAs with Lin28

21 January 2018

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Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis.

21 January 2018

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let-7 microRNAs in development, stem cells and cancer

21 January 2018

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Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation

21 January 2018

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Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells

21 January 2018

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Recent progress in the study of the genetics of height

21 January 2018

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c-Myc regulates mammalian body size by controlling cell number but not cell size

21 January 2018

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A common variant of HMGA2 is associated with adult and childhood height in the general population

21 January 2018

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Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice

21 January 2018

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Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse

21 January 2018

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Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

21 January 2018

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Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7

21 January 2018

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An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

21 January 2018

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The let-7 family of microRNAs

21 January 2018

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Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency

21 January 2018

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Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

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Opposing microRNA families regulate self-renewal in mouse embryonic stem cells

21 January 2018

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Identification of microRNAs regulating reprogramming factor LIN28 in embryonic stem cells and cancer cells.

21 January 2018

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LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro

21 January 2018

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Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells

21 January 2018

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Histone H2a mRNA interacts with Lin28 and contains a Lin28-dependent posttranscriptional regulatory element

21 January 2018

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Regulation of pluripotency and reprogramming by transcription factors

21 January 2018

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Direct cell reprogramming is a stochastic process amenable to acceleration

21 January 2018

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Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes

21 January 2018

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The long unwinding road of RNA helicases

21 January 2018

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From unwinding to clamping - the DEAD box RNA helicase family

21 January 2018

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RNA helicase A is necessary for translation of selected messenger RNAs

21 January 2018

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Primary Sequence and Secondary Structure Motifs in Spleen Necrosis Virus RU5 Confer Translational Utilization of Unspliced Human Immunodeficiency Virus Type 1 Reporter RNA

21 January 2018

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RNA helicase A modulates translation of HIV-1 and infectivity of progeny virions

21 January 2018

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Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/WRNA.1112

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26 August 2017

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PubMed ID

22467269