The role of myelin oligodendrocyte glycoprotein in autoimmune demyelination: a target for multiple sclerosis therapy? (Q38001792)

26 August 2017

The role of myelin oligodendrocyte glycoprotein in autoimmune demyelination: a target for multiple sclerosis therapy? (English)

1 reference

26 August 2017

0 references

1 reference

De-Hyung Lee

1

1 reference

PubMed ID

22494461

26 August 2017

Ralf A Linker

series ordinal

2

1 reference

PubMed ID

22494461

26 August 2017

language of work or name

English

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publication date

12 April 2012

1 reference

Expert Opinion on Therapeutic Targets

26 August 2017

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26 August 2017

16

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26 August 2017

5

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26 August 2017

451-462

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Histopathology and the blood-cerebrospinal fluid barrier in multiple sclerosis.

26 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Axonal transection in the lesions of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Glycoproteins of myelin sheaths

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

The in vitro demyelinating activity of sera from guinea pigs sensitized with whole CNS and with purified encephalitogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Multiple sclerosis: serum-induced demyelination in vitro. A light and electron microscope study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Myelin/oligodendrocyte glycoprotein is a unique member of the immunoglobulin superfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Myelin/oligodendrocyte glycoprotein is a member of a subset of the immunoglobulin superfamily encoded within the major histocompatibility complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Antibody facilitation of multiple sclerosis-like lesions in a nonhuman primate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Demyelination induced in aggregating brain cell cultures by a monoclonal antibody against myelin/oligodendrocyte glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Antibody responses in chronic relapsing experimental allergic encephalomyelitis: correlation of serum demyelinating activity with antibody titre to the myelin/oligodendrocyte glycoprotein (MOG).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Induction of persistently demyelinated lesions in the rat following the repeated adoptive transfer of encephalitogenic T cells and demyelinating antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Autoreactivity to myelin antigens: myelin/oligodendrocyte glycoprotein is a prevalent autoantigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Reactivity to myelin antigens in multiple sclerosis. Peripheral blood lymphocytes respond predominantly to myelin oligodendrocyte glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Multiple sclerosis: B- and T-cell responses to the extracellular domain of the myelin oligodendrocyte glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Identification of autoantibodies associated with myelin damage in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Demyelination in primate autoimmune encephalomyelitis and acute multiple sclerosis lesions: a case for antigen-specific antibody mediation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Regulation of myelin oligodendrocyte glycoprotein in different species throughout development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Experimental allergic encephalomyelitis: the balance between encephalitogenic T lymphocytes and demyelinating antibodies determines size and structure of demyelinated lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Myelin gene expression during demyelination and remyelination in aggregating brain cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Expression of the myelin basic protein gene locus in neurons and oligodendrocytes in the human fetal central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Myelin/oligodendrocyte glycoprotein expression during development in normal and myelin-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

The oligodendrocyte and its many cellular processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Biochemical and immunohistochemical studies with specific polyclonal antibodies directed against bovine myelin/oligodendrocyte glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Differential ultrastructural localization of myelin basic protein, myelin/oligodendroglial glycoprotein, and 2',3'-cyclic nucleotide 3'-phosphodiesterase in the CNS of adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Antibody cross-reactivity between myelin oligodendrocyte glycoprotein and the milk protein butyrophilin in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

T cells specific for the myelin oligodendrocyte glycoprotein mediate an unusual autoimmune inflammatory response in the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

MHC haplotype-dependent regulation of MOG-induced EAE in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Clinicopathological study of a myelin oligodendrocyte glycoprotein-induced demyelinating disease in LEW.1AV1 rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

A new focal EAE model of cortical demyelination: multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Inflammatory cortical demyelination in early multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Requirement for endocytic antigen processing and influence of invariant chain and H-2M deficiencies in CNS autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

T cell and antibody responses in remitting-relapsing experimental autoimmune encephalomyelitis in (C57BL/6 x SJL) F1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Autoantibody-mediated demyelination depends on complement activation but not activatory Fc-receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Inhibitory role of CD19 in the progression of experimental autoimmune encephalomyelitis by regulating cytokine response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Increased severity of experimental allergic encephalomyelitis in lyn-/- mice in the absence of elevated proinflammatory cytokine response in the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Spontaneous opticospinal encephalomyelitis in a double-transgenic mouse model of autoimmune T cell/B cell cooperation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Myelin/oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis in common marmosets: the encephalitogenic T cell epitope pMOG24-36 is presented by a monomorphic MHC class II molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Identification of a pathogenic antibody response to native myelin oligodendrocyte glycoprotein in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Epitope specificity of demyelinating monoclonal autoantibodies directed against the human myelin oligodendrocyte glycoprotein (MOG).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

B lymphocytes producing demyelinating autoantibodies: development and function in gene-targeted transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Biomarkers in multiple sclerosis: role of antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Antimyelin antibodies as a predictor of clinically definite multiple sclerosis after a first demyelinating event

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Lack of association between antimyelin antibodies and progression to multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Conformational epitopes of myelin oligodendrocyte glycoprotein are targets of potentially pathogenic antibody responses in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Antibodies as biological markers for pathophysiological processes in MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Myelin oligodendrocyte glycoprotein antibodies and multiple sclerosis in healthy young adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Multiple sclerosis in children: clinical diagnosis, therapeutic strategies, and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Acute disseminated encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Homogeneity of active demyelinating lesions in established multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

B cells and multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Clonally expanded plasma cells in the cerebrospinal fluid of MS patients produce myelin-specific antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Clonally expanded plasma cells in the cerebrospinal fluid of patients with central nervous system autoimmune demyelination produce "oligoclonal bands".

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Novel approaches for identifying target antigens of autoreactive human B and T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Intrathecal B-cell clonal expansion, an early sign of humoral immunity, in the cerebrospinal fluid of patients with clinically isolated syndrome suggestive of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Plasma exchange for severe optic neuritis: treatment of 10 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

A randomized trial of plasma exchange in acute central nervous system inflammatory demyelinating disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Plasmapheresis in fulminant acute disseminated encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Rituximab in relapsing-remitting multiple sclerosis: a 72-week, open-label, phase I trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

B-cell depletion with rituximab in relapsing-remitting multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Acute disseminated encephalomyelitis. Pathogenesis, diagnosis, treatment, and prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Rituximab reduces B cells and T cells in cerebrospinal fluid of multiple sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Response of patients with refractory myasthenia gravis to rituximab: a retrospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Neuromyelitis optica: pathogenicity of patient immunoglobulin in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

A phase III study evaluating the efficacy and safety of MBP8298 in secondary progressive MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Different responses to interferon beta-1b treatment in patients with neuromyelitis optica and multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

Late B Cell Depletion with a Human Anti-Human CD20 IgG1 Monoclonal Antibody Halts the Development of Experimental Autoimmune Encephalomyelitis in Marmosets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.677438

10.1517/14728222.2012.677438

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22494461