Innate immune activation and subversion of Mammalian functions by leishmania lipophosphoglycan. (Q38004492)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523640%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Innate immune activation and subversion of Mammalian functions by leishmania lipophosphoglycan (English)

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29 January 2020

2

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29 January 2020

Dario S. Zamboni

series ordinal

3

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29 January 2020

author name string

Luis H Franco

series ordinal

1

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29 January 2020

language of work or name

1 reference

22 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523640%20AND%20SRC:MED&resulttype=core&format=json

Journal of parasitology research

29 January 2020

published in

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29 January 2020

volume

2012

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29 January 2020

page(s)

165126

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Creative Commons Attribution 3.0 Unported

29 January 2020

copyright license

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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April 2022 Public Data File from Crossref

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Expression of a repeating phosphorylated disaccharide lipophosphoglycan epitope on the surface of macrophages infected with Leishmania donovani

6 September 2017

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Defective stimulus-response coupling in human monocytes infected with Leishmania donovani is associated with altered activation and translocation of protein kinase C

6 September 2017

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The role of promastigote secretory gel in the origin and transmission of the infective stage of Leishmania mexicana by the sandfly Lutzomyia longipalpis.

6 September 2017

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Leishmania major lipophosphoglycan: discrepancy in Toll-like receptor signaling

6 September 2017

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MyD88 is essential for clearance of Leishmania major: possible role for lipophosphoglycan and Toll‐like receptor 2 signaling

14 September 2017

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Lipophosphoglycan is not required for infection of macrophages or mice by Leishmania mexicana

14 September 2017

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14 September 2017

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Leishmania major activates IL-1 alpha expression in macrophages through a MyD88-dependent pathway

14 September 2017

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Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subver

28 September 2017

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Glycoconjugates isolated from Trypanosoma cruzi but not from Leishmania species membranes trigger nitric oxide synthesis as well as microbicidal activity in IFN-gamma-primed macrophages

28 September 2017

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The glycosyl-inositol-phosphate and dimyristoylglycerol moieties of the glycosylphosphatidylinositol anchor of the trypanosome variant-specific surface glycoprotein are distinct macrophage-activating factors

28 September 2017

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Glycosylphosphatidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of proinflammatory cytokines by macrophages.

28 September 2017

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Inhibition of phagolysosomal biogenesis by the Leishmania lipophosphoglycan

28 September 2017

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Golgi GDP-mannose uptake requires Leishmania LPG2. A member of a eukaryotic family of putative nucleotide-sugar transporters

28 September 2017

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The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes

28 September 2017

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Induction of inflammatory cytokine release from cultured human monocytes by C-reactive protein

28 September 2017

1 reference

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Glycoinositolphospholipids of Leishmania major inhibit nitric oxide synthesis and reduce leishmanicidal activity in murine macrophages

28 September 2017

1 reference

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Vaccination with phosphoglycan-deficient Leishmania major protects highly susceptible mice from virulent challenge without inducing a strong Th1 response.

28 September 2017

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Glycosylphosphatidylinositol toxin of Plasmodium induces nitric oxide synthase expression in macrophages and vascular endothelial cells by a protein tyrosine kinase-dependent and protein kinase C-dependent signaling pathway.

23 June 2018

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Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

23 June 2018

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Altered immune responses in mice lacking inducible nitric oxide synthase

23 June 2018

1 reference

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A ricin agglutinin-resistant clone of Leishmania donovani deficient in lipophosphoglycan.

23 June 2018

1 reference

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Binding and release of C3 from Leishmania donovani promastigotes during incubation in normal human serum.

23 June 2018

1 reference

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CR1, the C3b receptor, mediates binding of infective Leishmania major metacyclic promastigotes to human macrophages

23 June 2018

1 reference

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Released glycoconjugate of indigenous Leishmania major enhances survival of a foreign L. major in Phlebotomus papatasi.

23 June 2018

1 reference

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Serum resistance of metacyclic stage Leishmania major promastigotes is due to release of C5b-9.

23 June 2018

1 reference

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Developmental changes in the glycosylated phosphatidylinositols of Leishmania donovani. Characterization of the promastigote and amastigote glycolipids

23 June 2018

1 reference

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Stage-specific adhesion of Leishmania promastigotes to the sandfly midgut.

23 June 2018

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An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages

23 June 2018

1 reference

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A critical role for lipophosphoglycan in proinflammatory responses of dendritic cells to Leishmania mexicana.

31 August 2018

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A role for insect galectins in parasite survival.

31 August 2018

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Reconstitution of GDP-mannose transport activity with purified Leishmania LPG2 protein in liposomes.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

31 August 2018

Flypaper for parasites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

Persistence without pathology in phosphoglycan-deficient Leishmania major.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

Leishmania lipophosphoglycan (LPG) activates NK cells through toll-like receptor-2.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

Ether phospholipids and glycosylinositolphospholipids are not required for amastigote virulence or for inhibition of macrophage activation by Leishmania major.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

Organ-specific and stage-dependent control of Leishmania major infection by inducible nitric oxide synthase and phagocyte NADPH oxidase

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

Phosphoglycan repeat-deficient Leishmania mexicana parasites remain infectious to macrophages and mice

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

Lipophosphoglycan (LPG) and the identification of virulence genes in the protozoan parasite Leishmania

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

Type 1 interferon (IFNalpha/beta) and type 2 nitric oxide synthase regulate the innate immune response to a protozoan parasite

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

Deficiency in beta1,3-galactosyltransferase of a Leishmania major lipophosphoglycan mutant adversely influences the Leishmania-sand fly interaction.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

Expression of lipophosphoglycan, high-molecular weight phosphoglycan and glycoprotein 63 in promastigotes and amastigotes of Leishmania mexicana

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

Recognition of the major cell surface glycoconjugates of Leishmania parasites by the human serum mannan-binding protein.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

A specialized pathway affecting virulence glycoconjugates of Leishmania.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

Glycosylphosphatidylinositol toxin of Trypanosoma brucei regulates IL-1 alpha and TNF-alpha expression in macrophages by protein tyrosine kinase mediated signal transduction.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317186

Leishmania donovani lipophosphoglycan blocks NADPH oxidase assembly at the phagosome membrane

31 August 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F165126

Detection of lectin activity in Leishmania promastigotes and amastigotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F165126

Filamentous proteophosphoglycan secreted by Leishmania promastigotes forms gel-like three-dimensional networks that obstruct the digestive tract of infected sandfly vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F165126

Leishmania major lipophosphoglycan modulates the phenotype and inhibits migration of murine Langerhans cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F165126

Expression of a stage-specific lipophosphoglycan in Leishmania major amastigotes

21 January 2018

1 reference

12 December 2020

Inhibition of macrophage protein kinase C-mediated protein phosphorylation by Leishmania donovani lipophosphoglycan

1 reference

12 December 2020

Evidence that Leishmania donovani utilizes a mannose receptor on human mononuclear phagocytes to establish intracellular parasitism

1 reference

12 December 2020

Cell-mediated immune response in experimental visceral leishmaniasis. II. Oxygen-dependent killing of intracellular Leishmania donovani amastigotes

1 reference

12 December 2020

The mouse macrophage receptor for C3bi (CR3) is a major mechanism in the phagocytosis of Leishmania promastigotes

1 reference

12 December 2020

Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolysaccharide-responsive and lipopolysaccharide-nonresponsive murine macrophages

1 reference

12 December 2020

The major surface protein of Leishmania promastigotes is a protease

1 reference

12 December 2020

Leishmania donovani has distinct mannosylphosphoryltransferases for the initiation and elongation phases of lipophosphoglycan repeating unit biosynthesis

1 reference

12 December 2020

A role for oxygen-dependent mechanisms in killing of Leishmania donovani tissue forms by activated macrophages

1 reference

12 December 2020

Alteration of Leishmania donovani infection levels by selective impairment of macrophage signal transduction

1 reference

12 December 2020

Macrophage killing of Leishmania amazonensis amastigotes requires both nitric oxide and superoxide

1 reference

12 December 2020

Characterization of Leishmania donovani variant clones using anti-lipophosphoglycan monoclonal antibodies

1 reference

12 December 2020

C-reactive protein increases production of IL-1 alpha, IL-1 beta, and TNF-alpha, and expression of mRNA by human alveolar macrophages

1 reference

12 December 2020

The third component of complement (C3) is responsible for the intracellular survival of Leishmania major

1 reference

12 December 2020

Activation of the alternative complement pathway by Leishmania promastigotes: parasite lysis and attachment to macrophages

1 reference

12 December 2020

Immunochemical characterization of a glyco-inositol-phospholipid membrane antigen of Leishmania major

1 reference

12 December 2020

The involvement of TLR2 in cytokine and reactive oxygen species (ROS) production by PBMCs in response to Leishmania major phosphoglycans (PGs)

1 reference

12 December 2020

Agglutination of Leishmania promastigotes by midgut lectins from various species of phlebotomine sandflies

1 reference

12 December 2020

FISH analysis reveals aneuploidy and continual generation of chromosomal mosaicism in Leishmania major

1 reference

12 December 2020

Biogenesis of phagolysosomes: the 'kiss and run' hypothesis

1 reference

12 December 2020

Identifiers

DOI

10.1155/2012/165126

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523640%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523640%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523640%20AND%20SRC:MED&resulttype=core&format=json