HIV and inflammation: mechanisms and consequences (Q38005046)

26 August 2017

HIV and inflammation: mechanisms and consequences (English)

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26 August 2017

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Peter W Hunt

1

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PubMed ID

22528766

26 August 2017

language of work or name

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1 June 2012

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26 August 2017

Current HIV/AIDS reports

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26 August 2017

9

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26 August 2017

139-147

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26 August 2017

2

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https://scigraph.springernature.com/pub.10.1007/s11904-012-0118-8

26 August 2017

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cites work

Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiency

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https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Prognostic significance of plasma markers of immune activation, HIV viral load and CD4 T-cell measurements

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

CD8+ lymphocyte activation at human immunodeficiency virus type 1 seroconversion: development of HLA-DR+ CD38- CD8+ cells is associated with subsequent stable CD4+ cell levels. The Multicenter AIDS Cohort Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Predictive value of immunologic and virologic markers after long or short duration of HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

CD8+ T cells specific for EBV, cytomegalovirus, and influenza virus are activated during primary HIV infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Nonprogressive and progressive primate immunodeficiency lentivirus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

The level of monocyte turnover predicts disease progression in the macaque model of AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

T Cell Activation Is Associated with Lower CD4+T Cell Gains in Human Immunodeficiency Virus–Infected Patients with Sustained Viral Suppression during Antiretroviral Therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Determinants of CD4+ T cell recovery during suppressive antiretroviral therapy: association of immune activation, T cell maturation markers, and cellular HIV-1 DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Effect of baseline- and treatment-related factors on immunologic recovery after initiation of antiretroviral therapy in HIV-1-positive subjects: results from ACTG 384.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Immunologic failure despite suppressive antiretroviral therapy is related to activation and turnover of memory CD4 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Serum immune activation markers are persistently increased in patients with HIV infection after 6 years of antiretroviral therapy despite suppression of viral replication and reconstitution of CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Prevention of HIV-1 infection with early antiretroviral therapy

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Major clinical outcomes in antiretroviral therapy (ART)-naive participants and in those not receiving ART at baseline in the SMART study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Life expectancy of recently diagnosed asymptomatic HIV-infected patients approaches that of uninfected individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Multiple measures of HIV burden in blood and tissue are correlated with each other but not with clinical parameters in aviremic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Rapid onset of intestinal epithelial barrier dysfunction in primary human immunodeficiency virus infection is driven by an imbalance between immune response and mucosal repair and regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Impairment of the intestinal barrier is evident in untreated but absent in suppressively treated HIV-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Simian immunodeficiency virus-induced intestinal cell apoptosis is the underlying mechanism of the regenerative enteropathy of early infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Persistent microbial translocation and immune activation in HIV-1-infected South Africans receiving combination antiretroviral therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Increased carotid intima-media thickness in HIV patients is associated with increased cytomegalovirus-specific T-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Inflamm-aging. An evolutionary perspective on immunosenescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Peripheral blood markers of inflammation predict mortality and functional decline in high-functioning community-dwelling older persons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Cardiovascular disease, interleukin-6, and risk of mortality in older women: the women's health and aging study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

CD4+ count-guided interruption of antiretroviral treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Inflammatory and coagulation biomarkers and mortality in patients with HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Pretreatment levels of soluble cellular receptors and interleukin-6 are associated with HIV disease progression in subjects treated with highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Inflammation predicts changes in high-density lipoprotein particles and apolipoprotein A1 following initiation of antiretroviral therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Changes in inflammatory and coagulation biomarkers: a randomized comparison of immediate versus deferred antiretroviral therapy in patients with HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Markers of endothelial dysfunction, coagulation and tissue fibrosis independently predict venous thromboembolism in HIV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Towards a combined prognostic index for survival in HIV infection: the role of 'non-HIV' biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Relationship between a frailty-related phenotype and progressive deterioration of the immune system in HIV-infected men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Modification of the incidence of drug-associated symmetrical peripheral neuropathy by host and disease factors in the HIV outpatient study cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

An exploratory trial of cyclooxygenase type 2 inhibitor in HIV-1 infection: downregulated immune activation and improved T cell-dependent vaccine responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

The immune risk phenotype is associated with IL-6 in the terminal decline stage: Findings from the Swedish NONA immune longitudinal study of very late life functioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

CD4 T-cell hyperactivation and susceptibility to cell death determine poor CD4 T-cell recovery during suppressive HAART

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Nadir CD4 T Cell Count as Predictor and High CD4 T Cell Intrinsic Apoptosis as Final Mechanism of Poor CD4 T Cell Recovery in Virologically Suppressed HIV‐Infected Patients: Clinical Implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-012-0118-8

Plasma levels of soluble CD14 independently predict mortality in HIV infection

21 January 2018

1 reference

12 December 2020

Reduction of immune activation with chloroquine therapy during chronic HIV infection

1 reference

12 December 2020

Immunologic basis of cardiovascular disease in HIV-infected adults

1 reference

12 December 2020

Impact of CD8+ T-cell activation on CD4+ T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapy

1 reference

12 December 2020

Soluble CD163 made by monocyte/macrophages is a novel marker of HIV activity in early and chronic infection prior to and after anti-retroviral therapy

1 reference

12 December 2020

High dose atorvastatin decreases cellular markers of immune activation without affecting HIV-1 RNA levels: results of a double-blind randomized placebo controlled clinical trial

1 reference

12 December 2020

Hydroxychloroquine drastically reduces immune activation in HIV-infected, antiretroviral therapy-treated immunologic nonresponders

1 reference

12 December 2020

Limited immune restoration after 3 years' suppression of HIV-1 replication in patients with moderately advanced disease

1 reference

12 December 2020

Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of

1 reference

12 December 2020

Valganciclovir reduces T cell activation in HIV-infected individuals with incomplete CD4+ T cell recovery on antiretroviral therapy

1 reference

12 December 2020

Inflammation and mortality in HIV-infected adults: analysis of the FRAM study cohort

1 reference

12 December 2020

Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease

1 reference

12 December 2020

Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

1 reference

12 December 2020

Does an index composed of clinical data reflect effects of inflammation, coagulation, and monocyte activation on mortality among those aging with HIV?

1 reference

12 December 2020

Intensification of antiretroviral therapy with raltegravir or addition of hyperimmune bovine colostrum in HIV-infected patients with suboptimal CD4+ T-cell response: a randomized controlled trial

1 reference

12 December 2020

Association between systemic inflammation and incident diabetes in HIV-infected patients after initiation of antiretroviral therapy

1 reference

12 December 2020

Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly

1 reference

12 December 2020

B-cell stimulatory cytokines and markers of immune activation are elevated several years prior to the diagnosis of systemic AIDS-associated non-Hodgkin B-cell lymphoma.

1 reference

12 December 2020

Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection

1 reference

12 December 2020

Elevated levels of CD38+ CD8+ T cells in HIV infection add to the prognostic value of low CD4+ T cell levels: results of 6 years of follow-up. The Los Angeles Center, Multicenter AIDS Cohort Study

1 reference

12 December 2020

Association of C-reactive protein and HIV infection with acute myocardial infarction

1 reference

12 December 2020

Specific prebiotics modulate gut microbiota and immune activation in HAART-naive HIV-infected adults: results of the "COPA" pilot randomized trial

1 reference

12 December 2020

Markers of inflammation, coagulation, and renal function are elevated in adults with HIV infection

1 reference

12 December 2020

The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial

1 reference

12 December 2020

Higher levels of CRP, D-dimer, IL-6, and hyaluronic acid before initiation of antiretroviral therapy (ART) are associated with increased risk of AIDS or death

1 reference

12 December 2020

HIV-1 infection is associated with an earlier occurrence of a phenotype related to frailty

1 reference

12 December 2020

Microbial translocation is associated with sustained failure in CD4+ T-cell reconstitution in HIV-infected patients on long-term highly active antiretroviral therapy

1 reference

12 December 2020

10.1007/S11904-012-0118-8

Identifiers

DOI

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26 August 2017

1 reference

PubMed ID

22528766