Cutaneous metabolism of xenobiotics (Q38005642)

26 August 2017

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title

Cutaneous metabolism of xenobiotics (English)

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26 August 2017

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Kao J

1

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PubMed ID

2253557

26 August 2017

Carver MP

series ordinal

2

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PubMed ID

2253557

26 August 2017

language of work or name

English

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publication date

1 January 1990

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26 August 2017

Drug Metabolism Reviews

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26 August 2017

22

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26 August 2017

4

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26 August 2017

363-410

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Mechanism of percutaneous absorption. IV. Penetration of nonelectrolytes (alcohols) from aqueous solutions and from pure liquids.

26 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

The Skin as a Drug-Metabolizing Organ

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Skin structure and metabolism: relevance to the design of cutaneous therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Metabolism of androgens by human skin in acne.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Vitamin D metabolite production and function in keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

The metabolism of a series of polycyclic hydrocarbons by mouse skin maintained in short-term organ culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Aryl Hydrocarbon (Benzo[A]Pyrene) Hydroxylase: A Mixed-Function Oxygenase in Mouse Skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Cytochrome P-450 dependent deethylase activity in rat and hairless mouse skin microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Substrate specificity of the mouse skin mixed-function oxidase system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Major differences between lung, skin and liver in the microsomal metabolism of homologous series of resorufin and coumarin ethers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Percutaneous Absorption of 1-Naphthol in Man

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Percutaneous absorption and distribution of 2-naphthol in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Benzoyl peroxide: percutaneous penetration and metabolic disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Evaluation of monkey skin as a model for in vitro percutaneous penetration and metabolism of [3H]T-2 toxin in human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Evidence that coal tar is a mixed inducer of microsomal drug-metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Glutathione-S-Epoxide Transferase In Mouse Skin And Human Foreskin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Mechanisms of monooxygenase induction and inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Human skin aryl hydrocarbon hydroxylase. Induction by coal tar

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Induction of benzo[a]pyrene hydroxylase in skin and liver by cutaneous application of jute batching oil.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Skin tumor initiating activity of therapeutic crude coal tar as compared to other polycyclic aromatic hydrocarbons in SENCAR mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Microscope immersion oils: effects of skin application on cutaneous and hepatic drug-metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Topically applied nitropyrenes are potent inducers of cutaneous and hepatic monooxygenases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Comparative effects of topically applied nitrated arenes and their nonnitrated parent arenes on cutaneous and hepatic drug and carcinogen metabolism in neonatal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Cytochrome P-450-dependent O-dealkylase activity in mammalian skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Aryl Hydrocarbon Hydroxylase and Polycyclic Hydrocarbon Tumorigenesis: Effect of the Enzyme Inhibitor 7,8-Benzoflavone on Tumorigenesis and Macromolecule Binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Ellagic acid: a potent naturally occurring inhibitor of benzo[a]pyrene metabolism and its subsequent glucuronidation, sulfation and covalent binding to DNA in cultured BALB/C mouse keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Clotrimazole, an inhibitor of benzo[a]pyrene metabolism and its subsequent glucuronidation, sulfation, and macromolecular binding in BALB/c mouse cultured keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Purification and characterization of microsomal cytochrome P-450s

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Monoclonal antibodies directed characterization of epidermal and hepatic cytochrome P-450 isozymes induced by skin application of therapeutic crude coal tar.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Characterization of distinct forms of cytochromes P-450, epoxide metabolizing enzymes and UDP-glucuronosyltransferases in rat skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Factors affecting measurement of aryl hydrocarbon hydroxylase activity in mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Mouse Epidermal Aryl Hydrocarbon Hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Metabolism of benzo[a]pyrene in human epidermal keratinocytes in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

The activity of aryl hydrocarbon hydroxylase in adult human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Distribution of androgen metabolizing enzymes in isolated tissues of human forehead and axillary skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Fabry's disease: biochemical and histochemical studies on hair roots for carrier detection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Metabolism of androgens by isolated human beard hair follicles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Hydroxylation of dehydroepiandrosterone in human scalp hair folhcles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Metabolism of benzo[a]pyrene in isolated human scalp hair follicles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Human hair follicle benzo[a]pyrene and benzo[a]pyrene 7,8-diol metabolism: effect of exposure to a coal tar-containing shampoo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Increased brain uptake of morphine in the presence of the antihistamine tripelennamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Percutaneous absorption and excretion of xenobiotics after topical and intravenous administration to pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Dermal absorption and disposition of 1,3-diphenylguanidine in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Polychlorinated biphenyls (PCBs): dermal absorption, systemic elimination, and dermal wash efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

The guinea-pig: an animal model for human skin absorption of hydrocortisone, testosterone and benzoic acid?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Penetration of 5-Fluorouracil in Excised Skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

A diffusion-diffusion model for percutaneous drug absorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

A calculation of percutaneous drug absorption--II. Computation results.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Estimation of blood concentration of drugs after topical application from in vitro skin permeation data. I. Prediction by convolution and confirmation by deconvolution

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Estimation of blood concentration of drugs after topical application from in vitro skin permeation data. II. Approach by using diffusion model and compartment model

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

A theoretical consideration of percutaneous drug absorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Modeling and numerical computation of drug transport in laminates: model case evaluation of transdermal delivery system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Physical Model Evaluation of Topical Prodrug Delivery—simultaneous Transport and Bioconversion of vidarabine-5′-valerate I: Physical Model Development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Pharmacokinetics of drug permeation through human skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Skin as an active metabolizing barrier I: Theoretical analysis of topical bioavailability.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Correction factors for determining body exposure from forearm percutaneous absorption data

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Transdermal drug delivery and cutaneous metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Interpretation and prediction of the kinetics of transdermal drug delivery: oestradiol, hyoscine and timolol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Kinetic analysis of transdermal nitroglycerin delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

The effect of penetration enhancers on the kinetics of percutaneous absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Definition of a physiologic pharmacokinetic model of cutaneous drug distribution using the isolated perfused porcine skin flap

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

A physiologically relevant pharmacokinetic model of xenobiotic percutaneous absorption utilizing the isolated perfused porcine skin flap

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Transdermal bioavailability and first-pass skin metabolism: a preliminary evaluation with nitroglycerin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

In vitro skin evaporation and penetration characteristics of mosquito repellents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Evaporation of Diethyltoluamide from Human Skin in Vivo and in Vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Mass balance and dose accountability in percutaneous absorption studies: development of a nonocclusive application system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

The use and abuse of models

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Estimating the contribution by skin to systemic metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Interaction between benzo[a]pyrene and mouse skin in organ culture

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Skin penetration and metabolism of topically applied chemicals in six mammalian species, including man: an in vitro study with benzo[a]pyrene and testosterone.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

The effect of topical crude coal tar treatment on unstimulated hairless hamster skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Correlation of fluorescence intensity and carcinogenic potency of synthetic and natural petroleums in mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Methods for In Vitro Percutaneous Absorption Studies IV: the Flow-Through Diffusion Cell

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Maintenance of skin viability during in vitro percutaneous absorption/metabolism studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Development of an in vitro model for determining the fate of chemicals applied to skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Evaluation of animal models for predicting skin penetration in man*1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Percutaneous penetration in the hairless dog, weanling pig and grafted athymic nude mouse: evaluation of models for predicting skin penetration in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

A rapid method for preparing epidermal slices of reproducible thickness from excised rat skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Effect of serum-parathion interactions on cutaneous penetration of parathion in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Prolonged viability of human skin xenografts in rats by cyclosporine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Cutaneous blood flow and percutaneous absorption: a quantitative analysis using a laser Doppler velocimeter and a blood flow meter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

1-(3′-O-acyl)-β-glucosyl-N-dihydroxypentatria-contadienoylsphingosine, a major component of the glucosylceramides of pig and human epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

The isolated perfused porcine skin flap. III. Percutaneous absorption pharmacokinetics of organophosphates, steroids, benzoic acid, and caffeine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

Suicidal destruction of cytochrome P-450 during oxidative drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539009041089

10.3109/03602539009041089

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

2253557